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iASPP (PPP1R13L) (NM_006663) Human Untagged Clone
CAT＃: SC318309
PPP1R13L (untagged)-Human protein phosphatase 1, regulatory (inhibitor) subunit 13 like (PPP1R13L), transcript variant 2
CNY 6,072.00
CNY 7,220.00
| Cited in 2 publications. |
Product images
CNY 1,999.00
CNY 4,066.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | IASPP; NKIP1; RAI; RAI4 |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_006663 edited
CCGCCGCCAGCATGCCCCGGCCCGCGGGCCGCTCCGCCGCCAGCCACCCCCGCGGCCCTC GGCGGCCTGCGCTCGGCCCGGGGGCGCGGGAACCGCAGCCGGAGCCGGAGGCGGGAGCAG CGAGCCGGAGCCCCGGGCGCTCGAATGCAGGATGCTCGTGGTCCCCAGCATCCTTGAGCC ACCAGGAGTGAGGGCTGCTGCTCCCTGAGACCTGGCTCCAAGGAGGATGCCACAGCCGCC TGCCAGCTCCGGTCTGCACCATGAGTGATGAGCGGCGGCTGCCTGGCAGTGCAGTGGGCT GGCTGGTATGTGGGGGCCTCTCCCTGCTGGCCAATGCCTGGGGCATCCTCAGCGTTGGCG CCAAGCAGAAGAAGTGGAAGCCCTTGGAGTTCCTGCTGTGTACGCTCGCGGCCACCCACA TGCTAAATGTGGCCGTGCCCATCGCCACCTACTCCGTGGTGCAGCTGCGGCGGCAGCGCC CCGACTTCGAGTGGAATGAGGGTCTCTGCAAGGTCTTCGTGTCCACCTTCTACACCCTCA CCCTGGCCACCTGTTTCTCTGTCACCTCCCTCTCCTACCACCGCATGTGGATGGTCTGCT GGCCTGTCAACTACCGGCTGAGCAATGCCAAGAAGCAGGCGGTGCACACAGTCATGGGTA TCTGGATGGTGTCCTTCATCCTGTCGGCCCTGCCTGCCGTTGGCTGGCACGACACCAGCG AGCGCTTCTACACCCATGGCTGCCGCTTCATCGTGGCTGAGATCGGCCTGGGCTTTGGCG TCTGCTTCCTGCTGCTGGTGGGCGGCAGCGTGGCCATGGGCGTGATCTGCACAGCCATCG CCCTCTTCCAGACGCTGGCCGTGCAGGTGGGGCGCCAGGCCGACCACCGCGCCTTCACCG TGCCCACCATCGTGGTGGAGGACGCGCAGGGCAAGCGGCGCTCCTCCATCGATGGCTCGG AGCCCGCCAAAACCTCTCTGCAGACCACGGGCCTCGTGACCACCATAGTCTTCATCTACG ACTGCCTCATGGGCTTCCCTGTGCTGGTGGTGAGCTTCAGCAGCCTGCGGGCCGACGCCT CAGCGCCCTGGATGGCACTCTGCGTGCTGTGGTGCTCCGTGGCCCAGGCCCTGCTGCTGC CTGTGTTCCTCTGGGCCTGCGACCGCTACCGGGCTGACCTCAAAGCTGTCCGGGAGAAGT GCATGGCCCTCATGGCCAACGACGAGGAGTCAGACGATGAGACCAGCCTGGAAGGTGGCA TCTCCCCGGACCTGGTGTTGGAGCGCTCCCTGGACTATGGCTATGGAGGTGATTTTGTGG CCCTAGATAGGATGGCCAAGTATGAGATCTCCGCCCTGGAGGGGGGCCTGCCCCAGCTCT ACCCACTGCGGCCCTTGCAGGAGGACAAGATGCAATACCTGCAGGTCCCGCCCACGCGGC GCTTCTCCCACGACGATGCGGACGTGTGGGCCGCCGTCCCGCTGCCCGCCTTCCTGCCGC GCTGGGGCTCCGGCGAGGACCTGGCCGCCCTGGCGCACCTGGTGCTGCCTGCCGGGCCCG AGCGGCGCCGCGCCAGCCTCCTGGCCTTCGCGGAGGACGCACCACCGTCCCGCGCGCGCC GCCGCTCGGCCGAGAGCCTGCTGTCGCTGCGGCCCTCGGCCCTGGATAGCGGCCCGCGGG GAGCCCGCGACTCGCCCCCCGGCAGCCCGCGCCGCCGCCCCGGGCCCGGCCCCCGCTCCG CCTCGGCCTCGCTGCTGCCCGACGCCTTCGCCCTGACCGCCTTCGAGTGCGAGCCACAGG CCCTGCGCCGCCCGCCCGGGCCCTTCCCCGCTGCGCCCGCCGCCCCCGACGGCGCAGATC CCGGAGAGGCCCCGACGCCCCCAAGCAGCGCCCAGCGGAGCCCAGGGCCACGCCCCTCTG CGCACTCGCACGCCGGCTCTCTGCGCCCCGGCCTGAGCGCGTCGTGGGGCGAGCCCGGGG GGCTGCGCGCGGCGGGCGGCGGCGGCAGCACCAGCAGCTTCCTGAGTTCCCCCTCCGAGT CCTCGGGCTACGCCACGCTGCACTCGGACTCGCTGGGCTCCGCGTCCTAGGACCGCCGGC GCCTCCCCACGGACGCCAGGCAGGCCAGGCCGCTCTCCGGGGCCGCAGCACCAAAGACGC CCGCCTCCCCCCCGCGCGCAGACATGCGCCACCCCTCCCAGGGGTGAGGGGGCGTTGGCC TCAGCGTTTGTCTTCCGGCTCCTCCCAGCTGGCCTTGTCCCAGGGGCGACGGCTGCCCCG GACGACTGCGCTGGGCACCGCATGTCCCGGGCCGAGTGAGGTCGGGCCTGGGGAGCTGAG TGACATCCCAAGCTTGGGCTTGGGTAGTGAGTGACATGTGCACACGTCCAGCTGCGCCAT CACCAGCCCTGCGCAACAGGACGTCGGGAGCAGGGAACCTGAGACAGGGCCACTGCGGGA TCGGACAAAGCCCCGCTTTGGAGAGGCTGAGCTGGAGCCATTGGCCTCCCCAGGGGCTTT CCACCCACACTGCACCATAACCGCCACACCCTTCGGGGGGGGGGAGGGTACAGAGGGTCT CTAAGCACAGGGGTGTTCAGAGCCCGAACAAGCTTTGATCAGGTTTCCCTGCAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_006663 |
| Insert Size | 3100 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The ORF of this clone has been fully sequenced and found to be a perfect match to NM_006663.2. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_006663.2, NP_006654.2 |
| RefSeq Size | 3117 bp |
| RefSeq ORF | 2487 bp |
| Locus ID | 10848 |
| UniProt ID | Q8WUF5 |
| Domains | SH3, ANK |
| Protein Families | Transcription Factors |
| Gene Summary | IASPP is one of the most evolutionarily conserved inhibitors of p53 (TP53; MIM 191170), whereas ASPP1 (MIM 606455) and ASPP2 (MIM 602143) are activators of p53.[supplied by OMIM, Mar 2008] Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein. |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Suppression of iASPP-dependent aggressiveness in cervical cancer through reversal of methylation silencing of microRNA-124
,Dong, P;Xiong, Y;Watari, H;Hanley, SJ;Konno, Y;Ihira, K;Suzuki, F;Yamada, T;Kudo, M;Yue, J;Sakuragi, N;,
Sci Rep
,PubMed ID 27765948
[PPP1R13L]
|
|
Overexpression of iASPP-SV in glioma is associated with poor prognosis by promoting cell viability and antagonizing apoptosis
,Liu, X;Kang, J;Liu, F;Wen, S;Zeng, X;Liu, K;Luo, Y;Ji, X;Zhao, S;,
Tumour Biol.
,PubMed ID 26628298
[PPP1R13L]
|
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207150 | PPP1R13L (Myc-DDK-tagged)-Human protein phosphatase 1, regulatory (inhibitor) subunit 13 like (PPP1R13L), transcript variant 2 |
CNY 5,800.00 |
|
| RC207150L3 | Lenti ORF clone of Human protein phosphatase 1, regulatory (inhibitor) subunit 13 like (PPP1R13L), transcript variant 2, Myc-DDK-tagged |
CNY 7,700.00 |
|
| RC207150L4 | Lenti ORF clone of Human protein phosphatase 1, regulatory (inhibitor) subunit 13 like (PPP1R13L), transcript variant 2, mGFP tagged |
CNY 7,700.00 |
|
| RG207150 | PPP1R13L (tGFP-tagged) - Human protein phosphatase 1, regulatory (inhibitor) subunit 13 like (PPP1R13L), transcript variant 2 |
CNY 6,370.00 |
|
| SC115944 | PPP1R13L (untagged)-Human protein phosphatase 1, regulatory (inhibitor) subunit 13 like (PPP1R13L), transcript variant 2 |
CNY 7,240.00 |
