RBFOX2 (AK055213) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	dJ106I20.3; Fox-2; FOX2; fxh; HNRBP2; HRNBP2; RBM9; RTA
Vector	pCMV6 series
Sequence Data	Fully Sequenced ORF (showhide) >NCBI ORF sequence for AK055213, the custom clone sequence may differ by one or more nucleotides ATGGCGGAGGGCGCCCAGCCGCAGCAGCCGCCTCAGCTCGGGCCCGGCGCCGCCGCCCGG GGCATGAAGCGGGAGTCGGAGCTGGAGCTGCCGGTGCCCGGAGCGGGAGGAGACGGAGCC GATCCCGGCCTGAGCAAGCGGCCGCGCACTGAGGAGGCGGCGGCCGACGGTGGCGGCGGG ATGCAGAACGAGCCTCTGACTCCAGGTTATCATGGATTCCCAGCGCGGGACAGCCAGGGT AACCAGGAGCCTACAACAACTCCTGACGCAATGGTTCAGCCTTTTACTACCATCCCATTT CCACCACCTCCGCAGAATGGAATTCCCACAGAGTATGGGGTGCCACACACTCAAGACTAT GCCGGCCAGACCGGTGAGCATAACCTGACACTCTACGGAAGTACGCAAGCCCACGGGGAG CAGAGCAGCAACTCACCCAGCACACAAAATGGATCTCTTACGACAGAAGGTGGAGCACAG ACAGACGGCCAGCAGTCACAGACACAAAGTAGTGAAAATTCAGAGAGTAAATCTACCCCG AAACGGCTGCATGTCTCTAATATTCCATTCCGCTTCCGGGACCCTGACCTCCGGCAGATG TTTGGGCAGTTTGGCAAAATCCTAGATGTAGAAATAATCTTTAATGAACGTGGCTCTAAG GGATTCGGGTTCGTAACTTTCGAGAATAGTGCTGATGCAGACAGGGCCAGGGAGAAATTA CACGGCACCGTGGTAGAGGGCCGTAAAATCGAGGTGAATAATGCTACAGCACGTGTAATG ACCAATAAGAAGATGGTCACACCATATGCAAATGGTTGGAAATTAAGCCCAGTAGTTGGA GCTGTATATGGTCCGGAGTTATATGCAGCATTCAGCTTTCAAGCAGATGTGTCCCTAGGC AATGATGCAGCAGTGCCCCTATCAGGAAGAGGGGGTATCAACACTTACATTCCTTTAATC AGTCTCCCTTTAGTTCCTGGCTTCCCTTACCCTACTGCAGCCACCACGGCAGCCGCTTTC AGAGGAGCCCATTTGAGGGGCAGAGGGCGGACAGTATATGGTGCAGTCCGAGCGGTACCT CCAACAGCCATCCCCGCCTATCCAGGTGTGGTTTACCAGGACGGATTTTACGGTGCTGAC CTCTATGGTGGATATGCAGCCTACAGATATGCACAGCCTGCTACTGCAACCGCAGCCACC GCTGCTGCAGCCGCTGCAGCCGCTTACGGTGACGGTTATGGCAGGGTGTACACAGCCGAC CCCTACCATGCCCTTGCCCCTGCCGCTAGCTATGGAGTTGGCGCTGTGGCGAGTTTATAC CGAGGTGGCTACAGCCGATTTGCCCCCTAC
Restriction Sites	Please inquire
ACCN	AK055213
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation	This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	AK055213.1, BAB70875.1
RefSeq Size	1558 bp
RefSeq ORF	1353 bp
Locus ID	23543
Domains	RRM
Protein Families	Druggable Genome, Transcription Factors
Gene Summary	This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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