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GFRAL (NM_207410) Human Untagged Clone
CAT＃: SC308523
GFRAL (untagged)-Human GDNF family receptor alpha like (GFRAL)
CNY 5,856.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | bA360D14.1; C6orf144; GRAL; UNQ9356 |
| Vector | PCMV6-Neo |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>NCBI ORF sequence for NM_207410, the custom clone sequence may differ by one or more nucleotides
ATGATAGTGTTTATTTTCTTGGCTATGGGGTTAAGCTTGGAAAATGAATACACTTCCCAA ACCAATAATTGCACATATTTAAGAGAGCAATGCTTACGTGATGCAAATGGATGTAAACAT GCTTGGAGAGTAATGGAAGATGCCTGCAATGATTCAGATCCAGGTGACCCCTGCAAGATG AGGAATTCATCATACTGTAACCTGAGTATCCAGTACTTAGTGGAAAGCAATTTCCAATTT AAAGAGTGTCTTTGCACTGATGACTTCTATTGTACTGTGAACAAACTGCTTGGAAAAAAA TGTATCAATAAATCAGATAACGTGAAAGAGGATAAATTCAAATGGAATCTAACTACACGT TCCCATCATGGATTCAAAGGGATGTGGTCCTGTTTGGAAGTGGCAGAGGCATGTGTAGGG GATGTGGTCTGTAATGCACAGTTGGCCTCTTACCTTAAAGCTTGCTCAGCAAATGGAAAT CCGTGTGATCTGAAACAGTGCCAAGCAGCCATACGGTTCTTCTATCAAAATATACCTTTT AACATTGCCCAGATGTTGGCTTTTTGTGACTGTGCTCAATCTGATATACCTTGTCAGCAG TCCAAAGAAGCTCTTCACAGCAAGACATGTGCAGTGAACATGGTTCCACCCCCTACTTGC CTCAGTGTAATTCGCAGCTGCCAAAATGATGAATTATGCAGGAGGCACTATAGAACATTT CAGTCAAAATGCTGGCAGCGTGTGACTAGAAAGTGCCATGAAGATGAGAATTGCATTAGC ACCTTAAGCAAACAGGACCTCACTTGTTCAGGAAGTGATGACTGCAAAGCTGCTTACATA GATATCCTTGGGACGGTCCTTCAAGTGCAATGTACCTGTAGGACCATTACACAAAGTGAG GAATCTTTGTGTAAGATTTTCCAGCACATGCTTCATAGAAAATCATGTTTCAATTATCCA ACCCTGTCTAATGTCAAAGGCATGGCATTGTATACAAGAAAACATGCAAACAAAATCACT TTAACTGGATTTCATTCCCCCTTCAATGGAGAAGTAATCTATGCTGCCATGTGCATGACA GTCACCTGTGGAATCCTTCTGTTGGTTATGGTCAAGCTTAGAACTTCCAGAATATCAAGT AAAGCAAGAGATCCTTCATCGATCCAAATACCTGGAGAACTCTGA |
| Restriction Sites | Please inquire |
| ACCN | NM_207410 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_207410.1, NP_997293.1 |
| RefSeq Size | 1910 bp |
| RefSeq ORF | 1185 bp |
| Locus ID | 389400 |
| UniProt ID | Q6UXV0 |
| Protein Families | Druggable Genome, Transmembrane |
| Gene Summary | Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099). Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC213001 | GFRAL (Myc-DDK-tagged)-Human GDNF family receptor alpha like (GFRAL) |
CNY 5,488.00 |
|
| RC213001L1 | Lenti-ORF clone of GFRAL (Myc-DDK-tagged)-Human GDNF family receptor alpha like (GFRAL) |
CNY 7,888.00 |
|
| RC213001L2 | Lenti-ORF clone of GFRAL (mGFP-tagged)-Human GDNF family receptor alpha like (GFRAL) |
CNY 7,888.00 |
|
| RC213001L3 | Lenti-ORF clone of GFRAL (Myc-DDK-tagged)-Human GDNF family receptor alpha like (GFRAL) |
CNY 7,888.00 |
|
| RC213001L4 | Lenti-ORF clone of GFRAL (mGFP-tagged)-Human GDNF family receptor alpha like (GFRAL) |
CNY 7,888.00 |
|
| RG213001 | GFRAL (tGFP-tagged) - Human GDNF family receptor alpha like (GFRAL) |
CNY 7,088.00 |
