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PFKFB1 (NM_002625) Human Untagged Clone
CAT＃: SC303230
PFKFB1 (untagged)-Human 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 (PFKFB1)
CNY 3,656.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | F6PK; HL2K; PFRX |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_002625 edited
GGACAGGTAGTAAGATAGGAAGTGAGGCCAGGTACCTTGTGGGCAGTGATGTCATTCGGT GCGACTCCTAAGATGTCTCCAGAGATGGGAGAGCTCACCCAAACCAGGTTGCAGAAGATC TGGATTCCACACAGCAGCGGCAGCAGCAGGCTGCAACGGAGAAGGGGCTCATCCATACCC CAGTTTACCAATTCCCCCACAATGGTGATCATGGTGGGTTTACCAGCTCGAGGCAAGACC TATATCTCCACAAAGCTCACACGATATCTCAACTGGATAGGAACACCAACTAAAGTGTTT AATTTAGGCCAGTATCGACGAGAGGCAGTGAGCTACAAGAACTATGAATTCTTTCTTCCA GACAACATGGAAGCCCTGCAAATCAGGAAGCAGTGCGCCCTGGCAGCCCTGAAGGATGTT CACAACTATCTCAGCCATGAGGAAGGTCATGTTGCGGTTTTTGATGCCACCAACACTACC AGAGAACGACGGTCACTGATCCTGCAGTTTGCAAAAGAACATGGTTACAAGGTGTTTTTC ATTGAGTCCATTTGTAATGACCCTGGCATAATTGCAGAAAACATCAGGCAAGTGAAACTT GGCAGCCCTGATTATATAGACTGTGACCGGGAAAAGGTTCTGGAAGACTTTCTAAAGAGA ATTGAGTGCTATGAGGTCAACTACCAACCCTTGGATGAGGAACTGGACAGCCACCTGTCC TACATCAAGATCTTCGACGTGGGCACACGCTACATGGTGAACCGAGTGCAGGATCACATC CAGAGCCGCACAGTCTACTACCTCATGAATATCCATGTCACACCTCGCTCCATCTACCTT TGCCGACATGGCGAGAGTGAACTCAACATCAGAGGCCGCATCGGAGGTGACTCTGGCCTC TCAGTTCGCGGCAAGCAGTATGCCTATGCCCTGGCCAACTTCATTCAGTCCCAGGGCATC AGCTCCCTGAAGGTGTGGACCAGTCACATGAAGAGGACCATCCAGACAGCTGAGGCCCTG GGTGTCCCCTATGAGCAGTGGAAGGCCCTGAATGAGATTGATGCGGGTGTCTGTGAGGAG ATGACCTATGAAGAAATCCAGGAACATTACCCTGAAGAATTTGCACTGCGAGACCAAGAT AAATATCGCTACCGCTATCCCAAGGGAGAGTCCTATGAGGATCTGGTTCAGCGTCTGGAG CCAGTGATAATGGAGCTAGAACGACAGGAGAATGTACTGGTGATCTGCCACCAGGCTGTC ATGCGGTGCCTCCTGGCCTATTTCCTGGATAAAAGTTCAGATGAGCTTCCATATCTCAAG TGCCCTCTGCACACAGTGCTCAAACTCACTCCTGTGGCTTATGGCTGCAAAGTGGAATCC ATCTACCTGAATGTGGAGGCCGTGAACACACACCGGGAGAAGCCTGAGAATGTGGACATC ACCCGGGAACCTGAGGAAGCCCTGGATACTGTCCCAGCCCACTACTGAGCCCTTTCCAAG AAGTCAAACTGCCTGTGTCCTCATCGCCTTCCACCTTTAGGAAATGCTATCTTTGCTCTT CTCCTACTCTGCCTTGGCCTCACTGAGGCACCCCACTTCCAGTGAAGAAGTCCTCCGCAA CTCCCAAACAAGCCTCG |
| Restriction Sites | Please inquire |
| ACCN | NM_002625 |
| Insert Size | 1600 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The ORF of this clone has been fully sequenced and found to contain one SNP compared to NM_002625. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_002625.1, NP_002616.1 |
| RefSeq Size | 1741 bp |
| RefSeq ORF | 1416 bp |
| Locus ID | 5207 |
| UniProt ID | P16118 |
| Protein Families | Druggable Genome |
| Protein Pathways | Fructose and mannose metabolism |
| Gene Summary | This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012] Transcript Variant: This variant (1) encodes the longest isoform (1). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC224599 | PFKFB1 (Myc-DDK-tagged)-Human 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 (PFKFB1) |
CNY 3,656.00 |
|
| RC224599L1 | Lenti ORF clone of Human 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 (PFKFB1), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC224599L2 | Lenti ORF clone of Human 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 (PFKFB1), mGFP tagged |
CNY 5,890.00 |
|
| RC224599L3 | Lenti ORF clone of Human 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 (PFKFB1), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC224599L4 | Lenti ORF clone of Human 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 (PFKFB1), mGFP tagged |
CNY 5,890.00 |
|
| RG224599 | PFKFB1 (tGFP-tagged) - Human 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 (PFKFB1) |
CNY 4,370.00 |
