HIP2 (UBE2K) (BC006419) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene sequence for BC006419 edited GCAGCTGGGAGGACCCTCCCGCCCCAGGCAGAGGTGGGGGATATCCGGGAGTTCATTTCT GACCTCCTCGCTCTTCAGCACCTCCTTGAACTCCCGCTTGATTCGCTGCACCGCGATGTT GGCCATGTCTCCGCCCGCAGCTGATTCGTACCCGCCTCCTCCGCCACCGCTACGACCACC GCCACCGCCGCCACCTCTTCCTCCACCGCCTCCTCCCTCGGCGATTCAGACCTGAGCACA CGAACACTGCCACTACCACCCCGGCCGCCGCGCTCGCCTCAGTGTGGAATCACCTCCGCG CCCGGCCACCAAAATGGCGCCGGGTCGGCGCATGCGCACGACGTTGACCCGGCCGGGCGG CGCAGCCGCTCCTGTTGGAGCCCCCATACGCCCGAGCCACGAGCTCGCGTCTCGGCTGGG GCTGCGGCCGCGTGGCTCCGCCCTGCCGGCGTCTGGGGCCGCGAGGGTGCGGCTTCCAAG CTGGCCGGCCCTAGCCGGCCCCCCCGGCCCTTCCCGGCGCCTCCGCTCCTGTTTAAACCC GGGTGCTGTGGTCTGGGCTTCCAGCGCTGGCCTCTGACCGAAGGTTCGGGCGCAACCGAA CGGGTTTCCGACGCCGCACTCGGCTGGAACGCCGCCCTGACTCAGCTAGACCCGGAACCC GGAGGCTGAACGCCGTGTCTAGCGCAGGAAAACGCTCTCCCGGATCTCGGTCCGGCCCAT TTTCAGTTGGTGTAGCCCCAGAAAATCTACTGCAGTCGTTTTTGTTCTGCAACATTTATA GTACCACGATTATTCCCATCATCTCAGGTAGCACAGATTATTGAATTAAGGCTGGTTATT GTTGGATCAGATTGGGTTTGAGACAGGTACTCGGTGGAGAGGCCTGAGGGTGGGTTTAGA AGCCAGATGTTGCTCTTTGACCTATTTAATACCGAGCTTGACACACACACACAATCTCTC TCTCTCTCTCTCTCTCTCACACACACACACACACACACACACTCACTCCTATGCCCATCC CTAGAGTGTAGGGTGGGCCTAAGACTGCGCTTCTAACAAGTCTCCCAGTTGCTGCTGCTG TTGGTGCTGGTTCCGGGACCACATTATGAGAACCACTGAACTGAATGAAGCATGTGAAAA TTCACATATATTAAAGTGAAAATTGGAGAAATGGAAACAATTACAGTACCCTTCAGGGGA CTCGGGGTGGGGGAGGGGGAGCCTTATTTCTGTAAACCTAGGCCTCAAAGGTGCCTGGTG ATAGTAGGCACTCAATAAATATTGAATGAGTAAATGAGTACAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAA 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for BC006419 unedited NAAGTACAAAATTTGTAATACGACTCACTATNAGGGCCGGCCGCGAATTCGCACGAGGGC AGCTGGGAGGACCCTCCCGCCCCAGGCAGAGGTGGGGGATATCCGGGAGTTCATTTCTGA CCTCCTCGCTCTTCAGCACCTCCTTGAACTCCCGCTTGATTCGCTGCACCGCGATGTTGG CCATGTCTCCGCCCGCAGCTGATTCGTACCCGCCTCCTCCGCCACCGCTACGACCACCGC CACCGCCGCCACCTCTTCCTCCACCGCCTCCTCCCTCGGCGATTCAGACCTGAGCACACG AACACTGCCACTACCACCCCGGCCGCCGCGCTCGCCTCAGTGTGGAATCACCTCCGCGCC CGGCCACCAAAATGGCGCCGGGTCGGCGCATGCGCACGACGTTGACCCGGCCGGGCGGCG CAGCCGCTCCTGTTGGAGCCCCCATACGCCCGAGCCACGAGCTCGCGTCTCGGCTGGGGC TGCGGCCGCGTGGCTCCGCCCTGCCGGCGTCTGGGGCCGCGAGGGTGCGGCTTCCAAGCT GGCCGGCCCTAGCCGGCCCCCCCGGCCCTTCCCGGCGCCTCCGCTCCTGTTTAAACCCGG GTGCTGTGGTCTGGGCTTCCAGCGCTGGCCTCTGACCGAAGGTTCGGGCGCAACCGAACG GGTTTCCGACGCCGCACTCGGCTGGAACGCCGCCCTGACTCAGCTAGACCCGGAACCCGG AGGCTGAACGCCGTGTCTAGCGCAAGANAACGCTCTCCCGGATCTCGGTCCGGCCCATTT TCAGTTGGTGTAGCCCCAGAAAATCTACTGCAGTCGTTTTTGTTCTGCACATTTATAGTA CCACGATTATTCCCATCATCTCAGGTAGCACAGATTATTGATTANAGCTGGGTTATGNTG GATCAGATGGNGTT
Restriction Sites	Please inquire
ACCN	BC006419
Insert Size	1343 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	BC006419.1
RefSeq Size	1343 bp
Locus ID	3093
Protein Families	Druggable Genome, Transcription Factors
Protein Pathways	Ubiquitin mediated proteolysis
Gene Summary	The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

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