United States
Germany
Japan
United Kingdom
China
IL21 Receptor (IL21R) (NM_181078) Human Untagged Clone
CAT＃: SC123367
IL21R (untagged)-Human interleukin 21 receptor (IL21R), transcript variant 2
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CD360; IMD56; NILR |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_181078 edited
CCCCCAGAAGCCCATCAGACTGCCCCCAGCACACGGAATGGATTTCTGAGAAAGAAGCCG AAACAGAAGGCCCGTGGGAGTCAGCATGCCGCGTGGCTGGGCCGCCCCCTTGCTCCTGCT GCTGCTCCAGGGAGGCTGGGGCTGCCCCGACCTCGTCTGCTACACCGATTACCTCCAGAC GGTCATCTGCATCCTGGAAATGTGGAACCTCCACCCCAGCACGCTCACCCTTACCTGGCA AGACCAGTATGAAGAGCTGAAGGACGAGGCCACCTCCTGCAGCCTCCACAGGTCGGCCCA CAATGCCACGCATGCCACCTACACCTGCCACATGGATGTATTCCACTTCATGGCCGACGA CATTTTCAGTGTCAACATCACAGACCAGTCTGGCAACTACTCCCAGGAGTGTGGCAGCTT TCTCCTGGCTGAGAGCATCAAGCCGGCTCCCCCTTTCAACGTGACTGTGACCTTCTCAGG ACAGTATAATATCTCCTGGCGCTCAGATTACGAAGACCCTGCCTTCTACATGCTGAAGGG CAAGCTTCAGTATGAGCTGCAGTACAGGAACCGGGGAGACCCCTGGGCTGTGAGTCCGAG GAGAAAGCTGATCTCAGTGGACTCAAGAAGTGTCTCCCTCCTCCCCCTGGAGTTCCGCAA AGACTCGAGCTATGAGCTGCAGGTGCGGGCAGGGCCCATGCCTGGCTCCTCCTACCAGGG GACCTGGAGTGAATGGAGTGACCCGGTCATCTTTCAGACCCAGTCAGAGGAGTTAAAGGA AGGCTGGAACCCTCACCTGCTGCTTCTCCTCCTGCTTGTCATAGTCTTCATTCCTGCCTT CTGGAGCCTGAAGACCCATCCATTGTGGAGGCTATGGAAGAAGATATGGGCCGTCCCCAG CCCTGAGCGGTTCTTCATGCCCCTGTACAAGGGCTGCAGCGGAGACTTCAAGAAATGGGT GGGTGCACCCTTCACTGGCTCCAGCCTGGAGCTGGGACCCTGGAGCCCAGAGGTGCCCTC CACCCTGGAGGTGTACAGCTGCCACCCACCACGGAGCCCGGCCAAGAGGCTGCAGCTCAC GGAGCTACAAGAACCAGCAGAGCTGGTGGAGTCTGACGGTGTGCCCAAGCCCAGCTTCTG GCCGACAGCCCAGAACTCGGGGGGCTCAGCTTACAGTGAGGAGAGGGATCGGCCATACGG CCTGGTGTCCATTGACACAGTGACTGTGCTAGATGCAGAGGGGCCATGCACCTGGCCCTG CAGCTGTGAGGATGACGGCTACCCAGCCCTGGACCTGGATGCTGGCCTGGAGCCCAGCCC AGGCCTAGAGGACCCACTCTTGGATGCAGGGACCACAGTCCTGTCCTGTGGCTGTGTCTC AGCTGGCAGCCCTGGGCTAGGAGGGCCCCTGGGAAGCCTCCTGGACAGACTAAAGCCACC CCTTGCAGATGGGGAGGACTGGGCTGGGGGACTGCCCTGGGGTGGCCGGTCACCTGGAGG GGTCTCAGAGAGTGAGGCGGGCTCACCCCTGGCCGGCCTGGATATGGACACGTTTGACAG TGGCTTTGTGGGCTCTGACTGCAGCAGCCCTGTGGAGTGTGACTTCACCAGCCCCGGGGA CGAAGGACCCCCCCGGAGCTACCTCCGCCAGTGGGTGGTCATTCCTCCGCCACTTTCGAG CCCTGGACCCCAGGCCAGCTAATGAGGCTGACTGGATGTCCAGAGCTGGCCAGGCCACTG GGCCCTGAGCCAGAGACAAGGTCACCTGGGCTGTGATGTGAAGACACCTGCAGCCTTTGG TCTCCTGGATGGGCCTTTGAGCCTGATGTTTACAGTGTCTGTGTGTGTGTGTGCATATGT GTGTGTGTGCATATGCATGTGTGTGTGTGTGTGTGTCTTAGGTGCGCAGTGGCATGTCCA CGTGTGTGTGTGATTGCACGTGCCTGTGGGCCTGGGATAATGCCCATGGTACTCCATGCA TTCACCTGCCCTGTGCATGTCTGGACTCACGGAGCTCACCCATGTGCACAAGTGTGCACA GTAAACGTGTTTGTGGTCAACAGATGACAACAGCCGTCCTCCCTCCTAGGGTCTTGTGTT GCAAGTTGGTCCACAGCATCTCCGGGGCTTTGTGGGATCAGGGCATTGCCTGTGACTGAG GCGGAGCCCAGCCCTCCAGCGTCTGCCTCCAGGAGCTGCAAGAAGTCCATATTGTTCCTT ATCACCTGCCAACAGGAAGCGAAAGGGGATGGAGTGAGCCCATGGTGACCTCGGGAATGG CAATTTTTTGGGCGGCCCCTGGACGAAGGTCTGAATCCCGACTCTGATACCTTCTGGCTG TGCTACCTGAGCCAAGTCGCCTCCCCTCTCTGGGCTAGAGTTTCCTTATCCAGACAGTGG GGAAGGCATGACACACCTGGGGGAAATTGGCGATGTCACCCGTGTACGGTACGCAGCCCA GAGCAGACCCTCAATAAACGTCAGCTTCCTTCCTTCTGCGGCCAGAGCCGAGGCGGGCGG GGGTGAGAACATCAATCGTCAGCGACAGCCTGGGCACCCGCGGGGCCGTCCCGCCTGCAG AGGGCCACTCGGGGGGGTTTCCAGGCTTAAAATCAGTCCGTTTCGTCTCTTGGAAACAGC TCCCCACCAACCAAGATTTCTTTTTCTAACTTCTGCTACTAAGTTTTTAAAAATTCCCTT TATGCACCCAAGAGATATTTATTAAACACCAATTACGTAGCAGGCCATGGCTCATGGGAC CCACCCCCCGTGGCACTCATGGAGGGGGCTGCAGGTTGGAACTATGCAGTGTGCTCCGGC CACACATCCTGCTGGGCCCCCTACCCTGCCCCAATTCAATCCTGCCAATAAATCCTGTCT TATTTGTTCATCCTGGAGAATTGAAGGGAGGTCAAGTTGTTTGTCAATGATTTGTCAGAG AACCTGTTGAAATGTGAATTAAGAAGCTAAGAAAATAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAA >OriGene 5' read for NM_181078 unedited
NGGGAAAGTTCACATTTGTATACGACTCACTATAGGCGGCCGCGNAATTCGCACGAGGCC CCCATAAGCCCATCATACTGCCCCCAGCACACGGAATGGATTTCTGAGAAAGAAGCCGAA ACAGAAGGCCCGTGGGAGTCAGCATGCCGCGTGGCTGGGCCGCCCCCTTGCTCCTGCTGC TGCTCCAGGGAGGCTGGGGCTGCCCCGACCTCGTCTGCTACACCGATTACCTCCAGACGG TCATCTGCATCCTGGAAATGTGGAACCTCCACCCCAGCACGCTCACCCTTACCTGGCAAG ACCAGTATGAAGAGCTGAAGGACGAGGCCACCTCCTGCAGCCTCCACAGGTCGGCCCACA ATGCCACGCATGCCACCTACACCTGCCACATGGATGTATTCCACTTCATGGCCGACGACA TTTTCAGTGTCAACATCACAGACCAGTCTGGCAACTACTCCCAGGAGTGTGGCAGCTTTC TCCTGGCTGAGAGCATCAAGCCGGCTCCCCCTTTCAACGTGACTGTGACCTTCTCAGGAC AGTATAATATCTCCTGGCGCTCAGATTACGAAGACCCTGCCTTCTACATGCTGAAGGGCA AGCTTCAGTATGAGCTGCAGTACAGGAACCGGGGAGACCCCTGGGCTGTGAGTCCGAGGA GAAAGCTGATCTCAGTGGACTCAAGAAGTGTCTCCCTCCTCCCCCTGGAGTTCCGCANAG ACTCGAGCTATGAGCTGCAGGTGCGGGCAGGGCCCATGCCTGGCTCCTCCTACCAGGGAC CTGGAGTGAATGGAGTGACCCGGTCATCTTTCAGACCAGTCAGAGGAGTAAGGAAGGCTG NACCCTCACTGCTGCTTCTCT |
| Restriction Sites | Please inquire |
| ACCN | NM_181078 |
| Insert Size | 3014 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_181078.1, NP_851564.1 |
| RefSeq Size | 3361 bp |
| RefSeq ORF | 1617 bp |
| Locus ID | 50615 |
| UniProt ID | Q9HBE5 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway |
| Gene Summary | The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010] Transcript Variant: This variant (2) encodes the dominant isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202581 | IL21R (Myc-DDK-tagged)-Human interleukin 21 receptor (IL21R), transcript variant 2 |
CNY 3,990.00 |
|
| RC202581L3 | Lenti ORF clone of Human interleukin 21 receptor (IL21R), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC202581L4 | Lenti ORF clone of Human interleukin 21 receptor (IL21R), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG202581 | IL21R (tGFP-tagged) - Human interleukin 21 receptor (IL21R), transcript variant 2 |
CNY 4,370.00 |
其它IL21 Receptor产品
