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Cytochrome P450 26B (CYP26B1) (NM_019885) Human Untagged Clone
CAT＃: SC120799
CYP26B1 (untagged)-Human cytochrome P450, family 26, subfamily B, polypeptide 1 (CYP26B1)
CNY 5,728.00
| Cited in 2 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CYP26A2; P450RAI-2; P450RAI2; RHFCA |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Restriction Sites | Please inquire |
| ACCN | NM_019885 |
| Insert Size | 1539 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_019885.2, NP_063938.1 |
| RefSeq Size | 4567 bp |
| RefSeq ORF | 1539 bp |
| Locus ID | 56603 |
| UniProt ID | Q9NR63 |
| Protein Families | Druggable Genome, P450 |
| Protein Pathways | Retinol metabolism |
| Gene Summary | This gene encodes a member of the cytochrome P450 superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein is localized to the endoplasmic reticulum, and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms. Mutations in this gene are associated with radiohumeral fusions and other skeletal and craniofacial anomalies, and increased levels of the encoded protein are associated with atherosclerotic lesions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Identification of Tazarotenic Acid as the First Xenobiotic Substrate of Human Retinoic Acid Hydroxylase CYP26A1 and CYP26B1
,Foti, RS;Isoherranen, N;Zelter, A;Dickmann, LJ;Buttrick, BR;Diaz, P;Douguet, D;,
J. Pharmacol. Exp. Ther.
,PubMed ID 26937021
[CYP26B1]
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A Comparison of the Roles of Peroxisome Proliferator-Activated Receptor and Retinoic Acid Receptor on CYP26 Regulation
,Suzanne Tay, Leslie Dickmann, Vaishali Dixit, and Nina Isoherranen,
Mol. Pharmacol., Feb 2010; 77: 218 - 227
[CYP26B1]
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Documents
| Product Manuals |
| FAQs |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC221075 | CYP26B1 (Myc-DDK-tagged)-Human cytochrome P450, family 26, subfamily B, polypeptide 1 (CYP26B1) |
CNY 5,720.00 |
|
| RC221075L3 | Lenti-ORF clone of CYP26B1 (Myc-DDK-tagged)-Human cytochrome P450, family 26, subfamily B, polypeptide 1 (CYP26B1) |
CNY 6,370.00 |
|
| RC221075L4 | Lenti-ORF clone of CYP26B1 (mGFP-tagged)-Human cytochrome P450, family 26, subfamily B, polypeptide 1 (CYP26B1) |
CNY 6,370.00 |
|
| RG221075 | CYP26B1 (tGFP-tagged) - Human cytochrome P450, family 26, subfamily B, polypeptide 1 (CYP26B1) |
CNY 7,320.00 |
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