United States
Germany
Japan
United Kingdom
China
Retinoid X Receptor alpha (RXRA) (NM_002957) Human Untagged Clone
CAT＃: SC118299
RXRA (untagged)-Human retinoid X receptor, alpha (RXRA)
CNY 5,488.00
CNY 7,220.00
| Cited in 7 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | NR2B1 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_002957 edited
ATGGACACCAAACATTTCCTGCCGCTCGATTTCTCCACCCAGGTGAACTCCTCCCTCACC TCCCCGACGGGGCGAGGCTCCATGGCTGCCCCCTCGCTGCACCCGTCCCTGGGGCCTGGC ATCGGCTCCCCGGGACAGCTGCATTCTCCCATCAGCACCCTGAGCTCCCCCATCAACGGC ATGGGCCCGCCTTTCTCGGTCATCAGCTCCCCCATGGGCCCCCACTCCATGTCGGTGCCC ACCACACCCACCCTGGGCTTCAGCACTGGCAGCCCCCAGCTCAGCTCACCTATGAACCCC GTCAGCAGCAGCGAGGACATCAAGCCCCCCCTGGGCCTCAATGGCGTCCTCAAGGTCCCC GCCCACCCCTCAGGAAACATGGCTTCCTTCACCAAGCACATCTGCGCCATCTGCGGGGAC CGCTCCTCAGGCAAGCACTATGGAGTGTACAGCTGCGAGGGGTGCAAGGGCTTCTTCAAG CGGACGGTGCGCAAGGACCTGACCTACACCTGCCGCGACAACAAGGACTGCCTGATTGAC AAGCGGCAGCGGAACCGGTGCCAGTACTGCCGCTACCAGAAGTGCCTGGCCATGGGCATG AAGCGGGAAGCCGTGCAGGAGGAGCGGCAGCGTGGCAAGGACCGGAACGAGAATGAGGTG GAGTCGACCAGCAGCGCCAACGAGGACATGCCGGTGGAGAGGATCCTGGAGGCTGAGCTG GCCGTGGAGCCCAAGACCGAGACCTACGTGGAGGCAAACATGGGGCTGAACCCCAGCTCG CCGAACGACCCTGTCACCAACATTTGCCAAGCAGCCGACAAACAGCTTTTCACCCTGGTG GAGTGGGCCAAGCGGATCCCACACTTCTCAGAGCTGCCCCTGGACGACCAGGTCATCCTG CTGCGGGCAGGCTGGAATGAGCTGCTCATCGCCTCCTTCTCCCACCGCTCCATCGCCGTG AAGGACGGGATCCTCCTGGCCACCGGGCTGCACGTCCACCGGAACAGCGCCCACAGCGCA GGGGTGGGCGCCATCTTTGACAGGGTGCTGACGGAGCTTGTGTCCAAGATGCGGGACATG CAGATGGACAAGACGGAGCTGGGCTGCCTGCGCGCCATCGTCCTCTTTAACCCTGACTCC AAGGGGCTCTCGAACCCGGCCGAGGTGGAGGCGCTGAGGGAGAAGGTCTATGCGTCCTTG GAGGCCTACTGCAAGCACAAGTACCCAGAGCAGCCGGGAAGGTTCGCTAAGCTCTTGCTC CGCCTGCCGGCTCTGCGCTCCATCGGGCTCAAATGCCTGGAACATCTCTTCTTCTTCAAG CTCATCGGGGACACACCCATTGACACCTTCCTTATGGAGATGCTGGAGGCGCCGCACCAA ATGACTTAG >OriGene 5' read for NM_002957 unedited
ACAAAACTCTCTTCCCCGCCCGTTGNCNCACTAGGGCGGTAGCGTGTACGGTGGGAAGGT CTATATAAGCAGAGCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGG GCGGCCGCGAATTCGGCACGAGCCGCCGCCGCCACCGCAGCCGCCGGCTCCCCGCCGCCC GGGCCCGGGCCGGCCGCGCCGGGGGCCGCCGCGCCCGCCGCCCGCTGCCTGCGCCGCCGG CCGGGCATGAGTTAGTCGCAGACATGGACACCAAACATTTCCTGCCGCTCGATTTCTCCA CCCAGGTGAACTCCTCCCTCACCTCCCCGACGGGGCGAGGCTCCATGGCTGCCCCCTCGC TGCACCCGTCCCTGGGGCCTGGCATCGGCTCCCCGGGACAGCTGCATTCTCCCATCAGCA CCCTGAGCTCCCCCATCAACGGCATGGGCCCGCCTTTCTCGGTCATCAGCTCCCCCATGG GCCCCCACTCCATGTCGGTGCCCACCACACCCACCCTGGGCTTCAGCACTGGCAGCCCCC AGCTCAGCTCACCTATGAACCCCGTCAGCAGCAGCGAGGACATCAAGCCCCCCCTGGGCC TCAATGGCGTCCTCAAGGTCCCCGCCCACCCCTCAAGAAACATGGCTTCCTTCACCAAGC ACATCTGCGCCATCTGCGGGGACCGCTCCTCAGCAAGCACTATGGAGTGTACAGCTGCGA GGGGTGCAAGGGCTTCTTCAAGCGGACGGTGCGCAAGGACCTGACCTACACCTGCCGCGA CAACAAGGACTGCCCTGATTGACAGCGGCAGCGGGAACCGGTGCCAGTACTGCCGCTACC ANAAGTGCCTGGCCATGGGCATGAACCGGGAAGCCTTGCAAGAGGACCGCACCTT >OriGene 3' read for NM_002957 unedited
TGGGCCGAATCACTGTGNACCGCGCCCCTCTTNNCTANGATCGGTTTNCTTTTTTTTTTT TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTAAAAGGGGGGGGACA ACCCATTTTTTAAGCAAAACAGTGACAGGCTGGGCCCCAAAGTCCAAACAGGCCAGGCAA AAAAGGGCAGGGACAGGGCTCAGGCTGAAAAAAAATTTGGGGTCCACGCAGGGGGGCCAA AACGGGGGGGCACAAAGGATGGGCCCCCAGGCCTAAATCATTTGGGGGGGCGCCTCCAGC ATTTCCATAAGGAAGGGGTCAATGGGGGGGTCCCCGATGAGCTTGAAAAAAAAAAAATGT TCCAGGCAATTGACCCCCATGGAGCCCAAAACCACCAGGCGGAACAAGAACTTAACGAAC CTTCCCGGGTGCTCTGGGTACTTGGGCTTGCAAAAGGCCCCCAAGGACCCATAAACCTTT TCCCTCTAGGGCCTCCACCTTGGCCGGGTTCGAAAGCCCCTTGGAGTCAGGGTTAAAAAG GACAAAGGCGCCCAGGCAACCCAACTCCGTTTTGGCCATTTGCATGTCCCGCATTTTGGA CACAAGCTCCGTCAGCCACCTGTCAAAAATGGCGCCCACCCCTGCCCTATATGGCGCTTT TCCGGTGGACGTGCACCCCGGTGGCCAAGAAGATCCCCTCCTTCACGGCGAATGGAACGG TGGGAAAAAAGAAGCCAAAAAACACACTTATTCCAACCTGCCCCCCAAAAAGAATGACCC TGGTCTTCCAGGGGGCAACTCTTGAAAAATGTGGGGATCCGCCTTGGCCCCCCTCCACCA CGGGTGAAAAACCTGTTTTTCCGGCTGCTTGTGCAATGTTTGGGGAAAGGGTCCTCTCCG CGAACCTGGGGGTC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002957 |
| Insert Size | 1389 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_002957.3, NP_002948.1 |
| RefSeq Size | 5449 bp |
| RefSeq ORF | 1389 bp |
| Locus ID | 6256 |
| UniProt ID | P19793 |
| Domains | HOLI, zf-C4 |
| Protein Families | Druggable Genome, Nuclear Hormone Receptor, Transcription Factors |
| Protein Pathways | Adipocytokine signaling pathway, Non-small cell lung cancer, Pathways in cancer, PPAR signaling pathway, Small cell lung cancer, Thyroid cancer |
| Gene Summary | Retinoid X receptors (RXRs) and retinoic acid receptors (RARs) are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors function as transcription factors by binding as homodimers or heterodimers to specific sequences in the promoters of target genes. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014] Transcript Variant: This variant (1) encodes the longest isoform (a). |
Citations (7)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Identification and characterization of a FOXA2-regulated transcriptional enhancer at a type 2 diabetes intronic locus that controls GCKR expression in liver cells
,López Rodríguez, M;Kaminska, D;Lappalainen, K;Pihlajamäki, J;Kaikkonen, MU;Laakso, M;,
Genome Med
,PubMed ID 28683826
[RXRA]
|
|
Differential activation of human constitutive androstane receptor and its SV23 and SV24 splice variants by rilpivirine and etravirine
,Sharma, D;Lau, AJ;Sherman, MA;Chang, TK;,
Br. J. Pharmacol.
,PubMed ID 25363652
[RXRA]
|
|
Fetal bovine serum and human constitutive androstane receptor: Evidence for activation of the SV23 splice variant by artemisinin, artemether, and arteether in a serum-free cell culture system
,Lau, AJ;Chang, TK;,
Toxicol. Appl. Pharmacol. April 2014
,PubMed ID 24721719
[RXRA]
|
|
Transient Maternal Hypothyroxinemia Potentiates the Transcriptional Response to Exogenous Thyroid Hormone in the Fetal Cerebral Cortex Before the Onset of Fetal Thyroid Function: A Messenger and MicroRNA Profiling Study
,Dong, H;You, SH;Williams, A;Wade, MG;Yauk, CL;Thomas Zoeller, R;,
Cereb. Cortex, Jan 2014.
,PubMed ID 24436321
[RXRA]
|
|
Isoform-Selective Activation of Human Constitutive Androstane Receptor by Ginkgo biloba Extract: Functional Analysis of the SV23, SV24, and SV25 Splice Variants
,Aik Jiang Lau, Guixiang Yang, and Thomas K. H. Chang,
J. Pharmacol. Exp. Ther., Nov 2011; 339: 704 - 715.
[RXRA]
|
|
Differential Effect of Meclizine on the Activity of Human Pregnane X Receptor and Constitutive Androstane Receptor
,Aik Jiang Lau, Guixiang Yang, Ganesh Rajaraman, Christie C. Baucom, and Thomas K. H. Chang,
J. Pharmacol. Exp. Ther., Mar 2011; 336: 816 - 826
[RXRA]
|
|
Olfactomedin 4 is a novel target gene of retinoic acids and 5-aza-2'-deoxycytidine involved in human myeloid leukemia cell growth, differentiation, and apoptosis
,Wenli Liu, Hyun Woo Lee, Yueqin Liu, Ruihong Wang, and Griffin P. Rodgers,
Blood, Aug 2010; 10.1182/blood-2009-10-246439.
[RXRA]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210311 | RXRA (Myc-DDK-tagged)-Human retinoid X receptor, alpha (RXRA) |
CNY 3,656.00 |
|
| RC210311L1 | Lenti ORF clone of Human retinoid X receptor, alpha (RXRA), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC210311L2 | Lenti ORF clone of Human retinoid X receptor, alpha (RXRA), mGFP tagged |
CNY 5,890.00 |
|
| RC210311L3 | Lenti ORF clone of Human retinoid X receptor, alpha (RXRA), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC210311L4 | Lenti ORF clone of Human retinoid X receptor, alpha (RXRA), mGFP tagged |
CNY 5,890.00 |
|
| RG210311 | RXRA (tGFP-tagged) - Human retinoid X receptor, alpha (RXRA) |
CNY 4,370.00 |
其它Retinoid X Receptor alpha产品
