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CD162 (SELPLG) (NM_003006) Human Untagged Clone
CAT＃: SC118237
SELPLG (untagged)-Human selectin P ligand (SELPLG), transcript variant 2
CNY 2,950.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CD162; CLA; PSGL-1; PSGL1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_003006, the custom clone sequence may differ by one or more nucleotides
ATGCCTCTGCAACTCCTCCTGTTGCTGATCCTACTGGGCCCTGGCAACAGCTTGCAGCTGTGGGACACCT GGGCAGATGAAGCCGAGAAAGCCTTGGGTCCCCTGCTTGCCCGGGACCGGAGACAGGCCACCGAATATGA GTACCTAGATTATGATTTCCTGCCAGAAACGGAGCCTCCAGAAATGCTGAGGAACAGCACTGACACCACT CCTCTGACTGGGCCTGGAACCCCTGAGTCTACCACTGTGGAGCCTGCTGCAAGGCGTTCTACTGGCCTGG ATGCAGGAGGGGCAGTCACAGAGCTGACCACGGAGCTGGCCAACATGGGGAACCTGTCCACGGATTCAGC AGCTATGGAGATACAGACCACTCAACCAGCAGCCACGGAGGCACAGACCACTCAACCAGTGCCCACGGAG GCACAGACCACTCCACTGGCAGCCACAGAGGCACAGACAACTCGACTGACGGCCACGGAGGCACAGACCA CTCCACTGGCAGCCACAGAGGCACAGACCACTCCACCAGCAGCCACGGAAGCACAGACCACTCAACCCAC AGGCCTGGAGGCACAGACCACTGCACCAGCAGCCATGGAGGCACAGACCACTGCACCAGCAGCCATGGAA GCACAGACCACTCCACCAGCAGCCATGGAGGCACAGACCACTCAAACCACAGCCATGGAGGCACAGACCA CTGCACCAGAAGCCACGGAGGCACAGACCACTCAACCCACAGCCACGGAGGCACAGACCACTCCACTGGC AGCCATGGAGGCCCTGTCCACAGAACCCAGTGCCACAGAGGCCCTGTCCATGGAACCTACTACCAAAAGA GGTCTGTTCATACCCTTTTCTGTGTCCTCTGTTACTCACAAGGGCATTCCCATGGCAGCCAGCAATTTGT CCGTCAACTACCCAGTGGGGGCCCCAGACCACATCTCTGTGAAGCAGTGCCTGCTGGCCATCCTAATCTT GGCGCTGGTGGCCACTATCTTCTTCGTGTGCACTGTGGTGCTGGCGGTCCGCCTCTCCCGCAAGGGCCAC ATGTACCCCGTGCGTAATTACTCCCCCACCGAGATGGTCTGCATCTCATCCCTGTTGCCTGATGGGGGTG AGGGGCCCTCTGCCACAGCCAATGGGGGCCTGTCCAAGGCCAAGAGCCCGGGCCTGACGCCAGAGCCCAG GGAGGACCGTGAGGGGGATGACCTCACCCTGCACAGCTTCCTCCCTTAG >OriGene 5' read for NM_003006 unedited
GCGTCAGGATTTGTAATCACGACTTACTATAGGGNNCGGCCGCGCAATTCGGCACCGAGG GGACCTTGTCACTAAAGCAGAGAAGCCACTTCTTCTGGGCCCACGAGGCAGCTGTCCCAT GCTCTGCTGAGCACGGTGGTGCCATGCCTCTGCAACTCCTCCTGTTGCTGATCCTACTGG GCCCTGGCAACAGCTTGCAGCTGTGGGACACCTGGGCAGATGATATCCGAGAAAGCCTTG GGTCCCCTGCTTGCCCGGGACCGGAGACAGGCCACCGAATATGAGTACCTAGATTATGAT TTCCTGCCAGAAACGGAGCCTCCAGAAATGCTGAGGAACAGCACTGACACCACTCCTCTG ACTGGGCCTGGAACCCCTGAGTCTACCACTGTGGAGCCTGCTGCAAGGCGTTCTACTGGC CTGGATGCAGGAGGGGCAGTCACAGAGCTGACCACGGAGCTGGCCAACATGGGGAACCTG TCCACGGATTCAGCAGCTATGGAGATACAGACCACTCAACCAGCAGCCACGGAGGCACAG ACCACTCAACCAGTGCCCACGGAGGCACAGACCACTCCACTGGCAGCCACAGAGGCACAG ACAACTCGACTGACGGCCACGGAGGCACAGACCACTCCACTGGCAGCCACAGAGGCACAG ACCACTCCACCAGCAGCCACGGAAGCACAGACCACTCAACCCACAGGCCTGGAGGCACAG ACCACTGCACCAGCAGCCATGGAGGCACAGACCACTGCACCAGCAGCCATGGAAGCACAG ACCACTCCACCAGCAGCCATGGAGGCACAGACCACCTCAACCACAGCCATGGAGGCACAG ACCACTGCACCAGAAGCCACCGAGGCACAGACCAACTCACCCACAGCCACGGAGGCACGA CCACTCCACTGGCAGCCATGGAGGCCCTGTCCACAGACCCA >OriGene 3' read for NM_003006 unedited
ACCGAAAGCCGCNTTCGATAGTCGAGTTTTTTTCTTTTTTTTTTGTCCATCACATATTTA TTGCCTGCACTGGACCTGCAGTTGGGATACTGCAGTGAACAAGACAGAGTCCACCCTGGA AAGTGGCCACAGGGGAAGGCAAGAGGCGATAGCTGGGGGTCACTTGTCACTAGATGGAAG CTCCTTGGTCCACACAGTCCCAAAGAAAGGTCTTTCCTTGGGCCCACGAAACCCATCCCA GCCCTCACAGGCTGAACCTCACCCTGGGTTTTCCCAGAGAGGTGCCCAAGAAGACCCAAG CTGCCCCAAGTCAGAGGAGCAGCAGGAAACAGCCTCAGAAGTCCGTCACTCTTCAGTACT CCTCCCTTAGAATGTCCACTTCCTGTTTGGTGACCATGGCAACCAAAAGACAATGGCAGT GCAGTGCGTGTGGGATGGGGGAGCTCCATCTTTCTTGGGTACATGGGGAGGAGACTCCAG TGACCAGGAGAAGCGGGGAGAGCCATGGGAGATGTTACAGGGACCCAGAGAAGATGGGGG ACAGGAAAAAGGAGAGAATTTGCCTCAAGTAAACGGCCTACTGCCTTGGACCTCGGATGA AACGTGGCTGGGCTTCATCCGCGGAGGGAGGAAAGAGGTGGCTCCACTTGCCCGCCCGCT TGGCCCAAAGCTGCTCTTGACCCGTTTGGGTGGCCACAGGTTCTACCCTGAAAATCCCAT CCCCAGGGGCTCCGAGCAACCCCACAGCCGCCGAATGTGGACCCGGGCACTCAGGGGTGG CCCAGGAGAGCCCGTGTAACTGGGGCCCTTGCCACAACAAATGGCTTAGCGAGCTAAAGG CAGGAAACTGTGGCAGGCGGAGGCCATATCCTCTCCGGGATCTCCTTGGGCCTCTGGNGA CAAGCCCTCGGCTTTTTGGCACTTGGGAAAGGCCACCCTATTGCCTGTAG |
| Restriction Sites | ECoRI-NOT |
| ACCN | NM_003006 |
| Insert Size | 2170 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_003006.3, NP_002997.1 |
| RefSeq Size | 2550 bp |
| RefSeq ORF | 1209 bp |
| Locus ID | 6404 |
| UniProt ID | Q14242 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Cell adhesion molecules (CAMs) |
| Gene Summary | This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011] Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus, compared to isoform 1. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
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Transgenic expression of human P-selectin glycoprotein ligand-1 is not sufficient for enterovirus 71 infection in mice.
,null,
Archives of virology
,PubMed ID 22187102
[SELPLG]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206507 | SELPLG (Myc-DDK-tagged)-Human selectin P ligand (SELPLG), transcript variant 2 |
CNY 3,656.00 |
|
| RC206507L1 | Lenti ORF clone of Human selectin P ligand (SELPLG), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC206507L2 | Lenti ORF clone of Human selectin P ligand (SELPLG), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC206507L3 | Lenti ORF clone of Human selectin P ligand (SELPLG), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC206507L4 | Lenti ORF clone of Human selectin P ligand (SELPLG), transcript variant 2, mGFP tagged |
CNY 6,056.00 |
|
| RG206507 | SELPLG (tGFP-tagged) - Human selectin P ligand (SELPLG), transcript variant 2 |
CNY 4,370.00 |
|
| SC324184 | SELPLG (untagged)-Human selectin P ligand (SELPLG), transcript variant 2 |
CNY 2,950.00 |
