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Fibroblast activation protein, alpha (FAP) (NM_004460) Human Untagged Clone
CAT＃: SC117372
FAP (untagged)-Human fibroblast activation protein, alpha (FAP)
CNY 8,360.00
| Cited in 1 publication. |
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热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DPPIV; FAPA; FAPalpha; SIMP |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_004460 edited
GAATTCGGCACGAGGCCTTTTCAACGGTTTTCACAGATCCAGTGACCCACGCTCTGAAGA CAGAATTAGCTAACTTTCAAAAACATCTGGAAAAATGAAGACTTGGGTAAAAATCGTATT TGGAGTTGCCACCTCTGCTGTGCTTGCCTTATTGGTGATGTGCATTGTCTTACGCCCTTC AAGAGTTCATAACTCTGAAGAAAATACAATGAGAGCACTCACACTGAAGGATATTTTAAA TGGAACATTTTCTTATAAAACATTTTTTCCAAACTGGATTTCAGGACAAGAATATCTTCA TCAATCTGCAGATAACAATATAGTACTTTATAATATTGAAACAGGACAATCATATACCAT TTTGAGTAATAGAACCATGAAAAGTGTGAATGCTTCAAATTACGGCTTATCACCTGATCG GCAATTTGTATATCTAGAAAGTGATTATTCAAAGCTTTGGAGATACTCTTACACAGCAAC ATATTACATCTATGACCTTAGCAATGGAGAATTTGTAAGAGGAAATGAGCTTCCTCGTCC AATTCAGTATTTATGCTGGTCGCCTGTTGGGAGTAAATTAGCATATGTCTATCAAAACAA TATCTATTTGAAACAAAGACCAGGAGATCCACCTTTTCAAATAACATTTAATGGAAGAGA AAATAAAATATTTAATGGAATCCCAGACTGGGTTTATGAAGAGGAAATGCTTGCTACAAA ATATGCTCTCTGGTGGTCTCCTAATGGAAAATTTTTGGCATATGCGGAATTTAATGATAC GGATATACCAGTTATTGCCTATTCCTATTATGGCGATGAACAATATCCTAGAACAATAAA TATTCCATACCCAAAGGCTGGAGCTAAGAATCCCGTTGTTCGGATATTTATTATCGATAC CACTTACCCTGCGTATGTAGGTCCCCAGGAAGTGCCTGTTCCAGCAATGATAGCCTCAAG TGATTATTATTTCAGTTGGCTCACGTGGGTTACTGATGAACGAGTATGTTTGCAGTGGCT AAAAAGAGTCCAGAATGTTTCGGTCCTGTCTATATGTGACTTCAGGGAAGACTGGCAGAC ATGGGATTGTCCAAAGACCCAGGAGCATATAGAAGAAAGCAGAACTGGATGGGCTGGTGG ATTCTTTGTTTCAACACCAGTTTTCAGCTATGATGCCATTTCGTACTACAAAATATTTAG TGACAAGGATGGCTACAAACATATTCACTATATCAAAGACACTGTGGAAAATGCTATTCA AATTACAAGTGGCAAGTGGGAGGCCATAAATATATTCAGAGTAACACAGGATTCACTGTT TTATTCTAGCAATGAATTTGAAGAATACCCTGGAAGAAGAAACATCTACAGAATTAGCAT TGGAAGCTATCCTCCAAGCAAGAAGTGTGTTACTTGCCATCTAAGGAAAGAAAGGTGCCA ATATTACACAGCAAGTTTCAGCGACTACGCCAAGTACTATGCACTTGTCTGCTACGGCCC AGGCATCCCCATTTCCACCCTTCATGATGGACGCACTGATCAAGAAATTAAAATCCTGGA AGAAAACAAGGAATTGGAAAATGCTTTGAAAAATATCCAGCTGCCTAAAGAGGAAATTAA GAAACTTGAAGTAGATGAAATTACTTTATGGTACAAGATGATTCTTCCTCCTCAATTTGA CAGATCAAAGAAGTATCCCTTGCTAATTCAAGTGTATGGTGGTCCCTGCAGTCAGAGTGT AAGGTCTGTATTTGCTGTTAATTGGATATCTTATCTTGCAAGTAAGGAAGGGATGGTCAT TGCCTTGGTGGATGGTCGAGGAACAGCTTTCCAAGGTGACAAACTCCTCTATGCAGTGTA TCGAAAGCTGGGTGTTTATGAAGTTGAAGACCAGATTACAGCTGTCAGAAAATTCATAGA AATGGGTTTCATTGATGAAAAAAGAATAGCCATATGGGGCTGGTCCTATGGAGGATACGT TTCATCACTGGCCCTTGCATCTGGAACTGGTCTTTTCAAATGTGGTATAGCAGTGGCTCC AGTCTCCAGCTGGGAATATTACGCGTCTGTCTACACAGAGAGATTCATGGGTCTCCCAAC AAAGGATGATAATCTTGAGCACTATAAGAATTCAACTGTGATGGCAAGAGCAGAATATTT CAGAAATGTAGACTATCTTCTCATCCACGGAACAGCAGATGATAATGTGCACTTTCAAAA CTCAGCACAGATTGCTAAAGCTCTGGTTAATGCACAAGTGGATTTCCAGGCAATGTGGTA CTCTGACCAGAACCACGGCTTATCCGGCCTGTCCACGAACCACTTATACACCCACATGAC CCACTTCCTAAAGCAGTGTTTCTCTTTGTCAGACTAAAAACGATGCAGATGCAAGCCTGT ATCAGAATCTGAAAACCTTATATAAACCCCTCAGACAGTTTGCTTATTTTATTTTTTATG TTGTAAAATGCTAGTATAAACAAACAAATTAATGTTGTTCTAAAGGCTGTTAAAAAAAAG ATGAGGACTCAGAAGTTCAAGCTAAATATTGTTTACATTTTCTGGTACTCTGTGAAAGAA GAGAAAAGGGAGTCATGCATTTTGCTTTGGACACAGTGTTTTATCACCTGTTCATTTGAA GAAAAATAATAAAGTCAGAAGTTCAAGTGCTAAAAAAAAAAAAAAAAACTCGAC >OriGene 5' read for NM_004460 unedited
GGGTTTGAATTTGTATACGACTCCTATAGGGCGGCCGCGATTCGGCACGAGGCCTTTTCA ACGGTTTTCACANATCCAGTGACCCACGCTCTGAAGACAGAATTAGCTAACTTTCAAAAN ACATCTGGAAAAATGAAGACTTGGGTAAAAATCGTATTTGGAGTTGCCACCTCTGCTGTG CTTGCCTTATTGGTGATGTGCATTGTCTTACGCCCTTCAAGAGTTCATAACTCTGAAGAA AATACAATGAGAGCACTCACACTGAAGGATATTTTAAATGGAACATTTTCTTATAAAACA TTTTTTCCAAACTGGATTTCAGGACAAGAATATCTTCATCAATCTGCAGATAACAATATA GTACTTTATAATATTGAAACAGGACAATCATATACCATTTTGAGTAATAGAACCATGAAA AGTGTGAATGCTTCAAATTACGGCTTATCACCTGATCGGCAATTTGTATATCTAGAAAGT GATTATTCAAAGCTTTGGAGATACTCCTTACACAGCAACATATTACATCTATGACCTTAG CAATGGAGAATTTGTAAGAGGAAATGAGCTTCCTCGTCCAATTCAGTATTTATGCTGCTC GCCTGTTGGGAGTAAATTAGCATAATGTCTATCAAAACCATATCTATTTGAAACAAAGAC CAGAAGATCCACCTTTTNAAATAACATTTTATGGAAGAGAAAATAAAATATTTTATGGAA TCCCAGACTGGGTTTATGAAGAGGAAATGCCTGCTACAAAAATGCTCTTTGGAGCGCTCC TACAGGAAATTTTTGGCACATGCCGCACTTAACGACACCGAATACCCGTTTTTGCCTATT CCTATTTAGGCGATGAACCATTTCCTAAAACATAAACCTCCCATCACCCAGGGCTCGCAC CTAG >OriGene 3' read for NM_004460 unedited
CGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTAGCACTTGAACTTCTGACTT TATTATTTTTCTTCAAATGAACAGGTGATAAAACACTGTGTCCAAAGCAAAATGCATGAC TCCCTTTTCTCTTCTTTCACAGAGTACCAGAAAATGTAAACAATATTTAGCTTGAACTTC TGAGTCCTCATCTTTTTTTTAACAGCCTTTAGAACAACATTAATTTGTTTGTTTATACTA GCATTTTACAACATAAAAAATAAAATAAGCAAACTGTCTGAGGGGTTTATATAAGGTTTT CAGATTCTGATACAGGCTTGCATCTGCATCGTTTTTAGTCTGACAAAGAGAAACACTGCT TTAGGAAGTGGGTCATGTGGGTGTATAAGTGGTTCGTGGACAGGCCGGATAAGCCGTGGT TCTGGTCAGAGTACCACATTGCCTGGAAATCCACTTGTGCATTAACCAGAGCTTTAGCAA TCTGTGCTGAGTTTTGAAAGTGCACATTATCATCTGCTGTTCCGTGGATGAGAAGATAGT CTACATTTCTGAAATATTCTGCTCTTGCCATCACAGTTGAATTCTTATAGTGCTCAAGAT TATCATCCTTTGTTGGGAGACCCATGAATCTCTCTGTGTAGACAGACGCGTAATATTCCC AGCTGGAGACTGGAGCCACTGCTATACCACATTTGAAAAGACCAGTTCCAGATGCAAAGG CCAGTGATGAAACGTATCCTCCATAGGACCAGCCCCTATGGCTATCCTTTTTTATAATGA AACCCATTTCTATGAATTTTCTGACAGCGGAAATCTGCCTTCAAATTCTTAAACACCCAG CTTTGAATCCCTGCATTGAGGAGTTGGCACCTTGGAAACCTGTCCTTCACCATCACCAGG CAATGACCTCCCTTCCCTACTGCAGAAAAAATTCCATTTCCACCAACCCGCCTTCCCA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004460 |
| Insert Size | 2620 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_004460.2, NP_004451.2 |
| RefSeq Size | 2788 bp |
| RefSeq ORF | 2283 bp |
| Locus ID | 2191 |
| UniProt ID | Q12884 |
| Domains | Peptidase_S9, DPPIV_N_term |
| Protein Families | Druggable Genome, Protease, Transmembrane |
| Gene Summary | The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014] Transcript Variant: This variant (1) encodes the longer isoform (1). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Pericyte-targeting prodrug overcomes tumor resistance to vascular disrupting agents
,null,
The Journal of Clinical Investigation
,PubMed ID 28846068
[FAP]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC204692 | FAP (Myc-DDK-tagged)-Human fibroblast activation protein, alpha (FAP) |
CNY 3,990.00 |
|
| RC204692L1 | Lenti ORF clone of Human fibroblast activation protein, alpha (FAP), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC204692L2 | Lenti ORF clone of Human fibroblast activation protein, alpha (FAP), mGFP tagged |
CNY 5,890.00 |
|
| RC204692L3 | Lenti ORF clone of Human fibroblast activation protein, alpha (FAP), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC204692L4 | Lenti ORF clone of Human fibroblast activation protein, alpha (FAP), mGFP tagged |
CNY 5,890.00 |
|
| RG204692 | FAP (tGFP-tagged) - Human fibroblast activation protein, alpha (FAP) |
CNY 4,370.00 |
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