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LRRFIP1 (NM_004735) Human Untagged Clone
CAT＃: SC117183
LRRFIP1 (untagged)-Human leucine rich repeat (in FLII) interacting protein 1 (LRRFIP1), transcript variant 4
CNY 5,752.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | FLAP-1; FLAP1; FLIIAP1; GCF-2; GCF2; HUFI-1; TRIP |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC117183 sequence for NM_004735 edited (data generated by NextGen Sequencing)
ATGACCAGCCCCGCGGCCGCTCAAAGCCGGGAGATCGACTGTTTGAGCCCGGAAGCGCAG AAGCTGGCGGAAGCCCGGCTCGCTGCAAAACGGGCGGCCCGCGCGGAGGCTCGCGAGATC CGCATGAAGGAGCTGGAGCGGCAGCAGAAGGAGGAAGACAGTGAGCGCTACTCTCGTAGA TCCAGAAGAAACACATCGGCTTCTGATGAAGACGAGCGCATGTCAGTGGGTAGTCGTGGA AGCCTGAGGGTAGAAGAGAGACCAGAAAAAGATTTTACTGAGAAGGGGTCTCGTAACATG CCGGGCCTGTCTGCAGCCACGCTGGCCTCTCTGGGTGGGACTTCCTCTCGGAGAGGCAGC GGAGACACCTCCATCTCCATCGACACCGAGGCATCCATCAGGGAAATCAAGGACTCTCTA GCAGAAGTTGAAGAGAAATATAAGAAGGCTATGGTTTCCAATGCTCAGCTAGACAATGAA AAGACAAACTTCATGTACCAGGTTGATACCCTAAAAGATATGTTGCTGGAGCTTGAAGAA CAGCTGGCTGAATCTAGGCGGCAGTACGAAGAGAAAAACAAAGAATTTGAAAGGGAAAAA CACGCCCACAGTATACTGCAATTTCAGTTTGCTGAAGTCAAGGAGGCCCTGAAGCAAAGA GAGGAAATGCTCGAGAAACATGGAATAATCCTAAATTCAGAAATAGCTACCAATGGAGAG ACTTCCGACACCCTCAATAATGTTGGATACCAAGGTCCTACCAAGATGACAAAAGAAGAG TTAAATGCCCTCAAGTCGACAGGGGATGGGACCCTAGGAAGAGCCAGTGAAGTGGAGGTG AAAAATGAAATCGTGGCGAATGTGGGGAAAAGAGAAATCTTGCACAATACTGAGAAAGAA CAACACACAGAGGACACAGTGAAGGACTGTGTGGACATAGAGGTATTCCCTGCTGGTGAG AATACCGAGGACCAGAAATCCTCTGAAGACACTGCCCCATTCCTAGGAACCTTAGCAGGT GCTACCTATGAGGAACAGGTTCAAAGCCAAATTCTTGAGAGCAGTTCTCTCCCTGAAAAC ACAGTACAGGTTGAGTCAAATGAGGTCATGGGTGCACCAGATGACAGGACCAGAACTCCC CTTGAGCCATCCAACTGTTGGAGTGACTTAGATGGTGGGAACCACACAGAGAATGTGGGA GAGGCAGCAGTGACTCAGGTTGAAGAGCAGGCAGGCACAGTGGCCTCGTGTCCTTTAGGG CATAGTGATGACACAGTTTATCATGATGACAAATGTATGGTAGAGGTCCCCCAAGAGTTA GAGACAAGCACAGGGCATAGTTTAGAGAAAGAATTCACCAACCAGGAAGCAGCTGAGCCC AAGGAGGTTCCAGCGCACAGTACAGAAGTAGGTAGGGATCACAACGAAGAAGAGGGTGAA GAAACAGGATTAAGGGACGAGAAACCAATCAAGACAGAAGTTCCTGGTTCTCCAGCAGGA ACTGAGGGCAACTGTCAGGAAGCGACAGGTCCAAGTACAGTAGACACTCAAAATGAACCC TTAGATATGAAAGAGCCCGATGAAGAAAAGAGTGACCAACAGGGAGAGGCATTGGACTCA TCGCAGAAGAAGACAAAGAACAAGAAAAAGAAAAACAAGAAGAAAAAATCCCCAGTACCC GTAGAAACCCTTAAAGATGTTAAAAAAGAGTTAACGTATCAGAACACAGATTTAAGTGAA ATTAAGGAAGAAGAGCAGGTAAAGTCTACTGACAGAAAGTCAGCAGTGGAAGCCCAAAAC GAGGTGACTGAAAATCCAAAACAGAAAATTGCAGCAGAAAGCAGTGAAAATGTTGATTGT CCGGAGAATCCTAAAATTAAGTTGGATGGAAAACTTGACCAAGAAGGTGATGATGTACAA ACAGCAGCTGAGGAGGTACTAGCTGATGGAGACACATTAGATTTTGAGGATGACACCGTT CAATCATCAGGCCCGAGGGCTGGTGGTGAAGAATTAGATGAAGGTGTTGCAAAAGATAAT GCTAAAATAGATGGTGCCACTCAAAGCAGTCCTGCAGAACCAAAGAGCGAAGACGCAGAT CGCTGCACCCTGCCCGAACATGAAAGTCCCTCACAGGACATTAGTGATGCCTGTGAAGCA GAAAGTACAGAGAGGTGTGAGATGTCAGAACATCCAAGTCAGACCGTCAGGAAAGCTTTA GACAGCAATAGCCTAGAGAACGATGACTTGTCGGCACCAGGAAGAGAGCCAGGGCACTTC AATCCAGAAAGCAGAGAAGATACCAGAGGAGGGAATGAGAAGGGCAAAAGCAAAGAAGAC TGTACCATGTCCTAA Clone variation with respect to NM_004735.3 >OriGene 5' read for NM_004735 unedited
GGTTGGATTTGTATACGACTCCTATAGGGCGGCCGCGATTCGGCACGAGGCCGAGCCCGA CTCAGCCCGCGGCCACCTGCGCCCCGCCCCTGTCGGCCGCGCCCGAGCCCAGCGCCGCGA GCCGCTCCCCGGCGGGCTGGCTCCTGGCCCCGGAAGCGCGAGCGTTCACTTAGCGGCGAG TGGCTCCGTCTCCGCGGACAGAGCGCGCGCCCCCTGGCCCGGCCCGCGAGGGGCTCCCGG CGCGGTCCCCGAGCATTTCCCGCCGGGTGGAGCGGGCCGAGCCCGGCAGGATGACCAGCC CCGCGGCCGCTCAAAGCCGGGAGATCGACTGTTTGAGCCCGGAAGCGCAGAAGCTGGCGG AAGCCCGGCTCGCTGCAAAACGGGCGGCCCGCGCGGAGGCTCGCGAGATCCGCATGAAGG AGCTGGAGCGGCAGCAGAAGGAGGAAGACAGTGAGCGCTACTCTCGTAGATCCAGAAGAA ACACATCCGGCTTCTGATGAAGACGAGCGCATGTCAGTGGGCAGTCGTGGAAGCCTGATG GTAGAAGAGAGACCAGAAAAAGATTTTACTGAGAAGGGGTCTCGTAACATGCCGGGCCTG TCTGCAGCCACCGCTGGCCTCTCTGGGTGGGACTTCCTCTCGGAGAGGCAGCGGAGACAC CTCCATCTCCATCGACACCGAGGCATTCATCAGGGAAATCAAAGACTCTCTACCAGAATT TGAAGAGAAATACTACAAGGCTATGGTTTCCCATGCTCAGCTATACCACGAAAAGACAAA CTTCATGGTCCCAGGGTGATACGCTCAAAGATATGTTGCCTGAGCTTTGAAGAACAGCTG GCTGAATCTCAGCGGCGTTCCGAGCAAGAAAACCACGCAATTGCCAAGGGAGAAACATCC CCAACAGTATACTGCATTTTCATGTCTGCTGAAGCTCACG >OriGene 3' read for NM_004735 unedited
GCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTAGAGACAGTGTCTCACTCTGTCTCCC AGGCTAGAGTACAGTGTGCAATCATAGCTCACTGCAGCCTTGAACTCCTGGCCTCAAGCA ATCCTCCCACCTTGGCTTCCCAATGTGCTAGGTTTACAGGCGTGAAAACATTGTGTTGTG TGTGTGTGTGTTTTTTTTTTTTTTTTTAAACAGAGTTTCGCTCTTGTTGTCCAGGCTGGA GTACAATGGCTTGATCTTGGCTCACTGCAATCTCTGCCTCGCAGGTTCAAGCGATTCTCC TGCCTCAGCCTCTGGAGTGGCTGGGATTACAGGCGCCCACCATCACGCCCGGCCAATTTT TTGTATTTTTAGTAAAGACAGGGTTTCACCATGTTGGCCAGGCTGGCCTCGAACTCTTGA CCTCAGGTGATCCACCTGCCTTGGCCTCCCAATGTACTGAGATTACAGGCATGAGCCACC ACGCCCGGCCAAAAACATTTAAAAAATGACTGTCCCTGCTCAAATACTGCAGTAGGAAAT GTAATTTGACATATATCACTTCCAGAAAAAAACTTTAAATCTTTCTATAAAATGAATTTG ATACATCATCAGCATGAAGTGAAGTAAAATCTCTTACAAGTAATTCAGGTATATAACATG AGATCCAAAGTATCGGTTCAAGACAAAGACTCTATGAGGTAAGGCAAATAAGCCCCTATG CTTTAGACATTACTTGTATCCCTAAAGATATTGTTCAAGCGCAAATTTATATTCAAGACC TATTGCTTTGGCTGTTATCTCCTTAATAAATACCTACCGGTATATGCACTTTTTAATCAA TTGAAGGCCCCTTGGGACAGAACTAATTAATTCAATTTTCCTAAACCAAGTCAAAAGCCT TTGGCTTCATTAAAGCCGTTTTTGGCAAAAACCCTTCTTTACCAAGAAATAAAGCCCTTT ATAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004735 |
| Insert Size | 4260 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_004735.2, NP_004726.1 |
| RefSeq Size | 3648 bp |
| RefSeq ORF | 2355 bp |
| Locus ID | 9208 |
| UniProt ID | Q32MZ4 |
| Protein Families | Transcription Factors |
| Gene Summary | Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (4) lacks an in-frame exon in the coding region, compared to variant 3. The resulting isoform (4) lacks an internal segment, compared to isoform 3. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a ß-catenin-dependent pathway
,Pengyuan Yang, Huazhang An, Xingguang Liu, Mingyue Wen, Yuanyuan Zheng, Yaocheng Rui, Xuetao Cao,
Nature Immunology 11, 487-494 (9 May 2010) doi:10.1038/ni.1876 Article
[LRRFIP1]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC216265 | LRRFIP1 (Myc-DDK-tagged)-Human leucine rich repeat (in FLII) interacting protein 1 (LRRFIP1), transcript variant 4 |
CNY 5,744.00 |
|
| RC216265L1 | Lenti ORF clone of Human leucine rich repeat (in FLII) interacting protein 1 (LRRFIP1), transcript variant 4, Myc-DDK-tagged |
CNY 8,144.00 |
|
| RC216265L2 | Lenti ORF clone of Human leucine rich repeat (in FLII) interacting protein 1 (LRRFIP1), transcript variant 4, mGFP tagged |
CNY 10,170.00 |
|
| RC216265L3 | Lenti ORF clone of Human leucine rich repeat (in FLII) interacting protein 1 (LRRFIP1), transcript variant 4, Myc-DDK-tagged |
CNY 10,170.00 |
|
| RC216265L4 | Lenti ORF clone of Human leucine rich repeat (in FLII) interacting protein 1 (LRRFIP1), transcript variant 4, mGFP tagged |
CNY 10,170.00 |
|
| RG216265 | LRRFIP1 (tGFP-tagged) - Human leucine rich repeat (in FLII) interacting protein 1 (LRRFIP1), transcript variant 4 |
CNY 9,120.00 |
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