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Ku80 (XRCC5) (NM_021141) Human Untagged Clone
CAT＃: SC112985
XRCC5 (untagged)-Human X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) (XRCC5)
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | KARP-1; KARP1; KU80; Ku86; KUB2; NFIV |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC112985 sequence for NM_021141 edited (data generated by NextGen Sequencing)
ATGGTGCGGTCGGGGAATAAGGCAGCTGTTGTGCTGTGTATGGACGTGGGCTTTACCATG AGTAACTCCATTCCTGGTATAGAATCCCCATTTGAACAAGCAAAGAAGGTGATAACCATG TTTGTACAGCGACAGGTGTTTGCTGAGAACAAGGATGAGATTGCTTTAGTCCTGTTTGGT ACAGATGGCACTGACAATCCCCTTTCTGGTGGGGATCAGTATCAGAACATCACAGTGCAC AGACATCTGATGCTACCAGATTTTGATTTGCTGGAGGACATTGAAAGCAAAATCCAACCA GGTTCTCAACAGGCTGACTTCCTGGATGCACTAATCGTGAGCATGGATGTGATTCAACAT GAAACAATAGGAAAGAAGTTTGAGAAGAGGCATATTGAAATATTCACTGACCTCAGCAGC CGATTCAGCAAAAGTCAGCTGGATATTATAATTCATAGCTTGAAGAAATGTGACATCTCC CTGCAATTCTTCTTGCCTTTCTCACTTGGCAAGGAAGATGGAAGTGGGGACAGAGGAGAT GGCCCCTTTCGCTTAGGTGGCCATGGGCCTTCCTTTCCACTAAAAGGAATTACCGAACAG CAAAAAGAAGGTCTTGAGATAGTGAAAATGGTGATGATATCTTTAGAAGGTGAAGATGGG TTGGATGAAATTTATTCATTCAGTGAGAGTCTGAGAAAACTGTGCGTCTTCAAGAAAATT GAGAGGCATTCCATTCACTGGCCCTGCCGACTGACCATTGGCTCCAATTTGTCTATAAGG ATTGCAGCCTATAAATCGATTCTACAGGAGAGAGTTAAAAAGACTTGGACAGTTGTGGAT GCAAAAACCCTAAAAAAAGAAGATATACAAAAAGAAACAGTTTATTGCTTAAATGATGAT GATGAAACTGAAGTTTTAAAAGAGGATATTATTCAAGGGTTCCGCTATGGAAGTGATATA GTTCCTTTCTCTAAAGTGGATGAGGAACAAATGAAATATAAATCGGAGGGGAAGTGCTTC TCTGTTTTGGGATTTTGTAAATCTTCTCAGGTTCAGAGAAGATTCTTCATGGGAAATCAA GTTCTAAAGGTCTTTGCAGCAAGAGATGATGAGGCAGCTGCAGTTGCACTTTCCTCCCTG ATTCATGCTTTGGATGACTTAGACATGGTGGCCATAGTTCGATATGCTTATGACAAAAGA GCTAATCCTCAAGTCGGCGTGGCTTTTCCTCATATCAAGCATAACTATGAGTGTTTAGTG TATGTGCAGCTGCCTTTCATGGAAGACTTGCGGCAATACATGTTTTCATCCTTGAAAAAC AGTAAGAAATATGCTCCCACCGAGGCACAGTTGAATGCTGTTGATGCTTTGATTGACTCC ATGAGCTTGGCAAAGAAAGATGAGAAGACAGACACCCTTGAAGACTTGTTTCCAACCACC AAAATCCCAAATCCTCGATTTCAGAGATTATTTCAGTGTCTGCTGCACAGAGCTTTACAT CCCCGGGAGCCTCTACCCCCAATTCAGCAGCATATTTGGAATATGCTGAATCCTCCCGCT GAGGTGACAACAAAAAGTCAGATTCCTCTCTCTAAAATAAAGACCCTTTTTCCTCTGATT GAAGCCAAGAAAAAGGATCAAGTGACTGCTCAGGAAATTTTCCAAGACAACCATGAAGAT GGACCTACAGCTAAAAAATTAAAGACTGAGCAAGGGGGAGCCCACTTCAGCGTCTCCAGT CTGGCTGAAGGCAGTGTCACCTCTGTTGGAAGTGTGAATCCTGCTGAAAACTTCCGTGTT CTAGTGAAACAGAAGAAGGCCAGCTTTGAGGAAGCGAGTAACCAGCTCATAAATCACATC GAACAGTTTTTGGATACTAATGAAACACCGTATTTTATGAAGAGCATAGACTGCATCCGA GCCTTCCGGGAAGAAGCCATTAAGTTTTCAGAAGAGCAGCGCTTTAACAACTTCCTGAAA GCCCTTCAAGAGAAAGTGGAAATTAAACAATTAAATCATTTCTGGGAAATTGTTGTCCAG GATGGAATTACTCTGATCACCAAAGAGGAAGCCTCTGGAAGTTCTGTCACAGCTGAGGAA GCCAAAAAGTTTCTGGCCCCCAAAGACAAACCAAGTGGAGACACAGCAGCTGTATTTGAA GAAGGTGGTGATGTGGACGATTTATTGGACATGATATAG Clone variation with respect to NM_021141.3 >OriGene 5' read for NM_021141 unedited
AGTTTGGATTTTGTNATCCGACTTCATATAGGGCGGCCGCGCAATTCGCACGAGGCCTCG TGCCGAATTCGGCACGAGGCCGGAAGCGAGTTGCGACACGGCAGGTTCCCGCCCGGAAGA AGCGACCAAAGCGCCTGAGGACCGGCAACATGGTGCGGTCGGGGAATAAGGCAGCTGTTG TGCTGTGTATGGACGTGGGCTTTACCATGAGTAACTCCATTCCTGGTATAGAATCCCCAT TTGAACAAGCAAAGAAGGTGATAACCATGTTTGTACAGCGACAGGTGTTTGCTGAGAACA AGGATGAGATTGCTTTAGTCCTGTTTGGTACAGATGGCACTGACAATCCCCTTTCTGGTG GGGATCAGTATCAGAACATCACAGTGCACAGACATCTGATGCTACCAGATTTTGATTTGC TGGAGGACATTGAAAGCAAAATCCAACCAGGTTCTCAACAGGCTGACTTCCTGGATGCAC TAATCGTGAGCATGGATGTGATTCAACATGAAACAATAGGAAAGAAGTTTGAGAAGAGGC ATATTGAAATATTCACTGACCTCAGCAGCCGATTCAGCAAAAGTCAGCTGGATATTATAA TTCATAGCTTGAAGAAATGTGACATCTCCCTGCAATTCTTCTTGCCTTTCTCACTTGGCA AGGAAGATGGAAGTGGGGACAGAGGAGATGGCCCCTTTCGCTTAGGTGGCCATGGGCCTT CCTTTCCACTAAAAGGAATTACCGAACAGCANANAGAAGGTCTTGAGATAGTGAAAATGG TGATGATATCTTTAGAAGGTGAAGATGGGTTGGNATGAAAATTTATTCATTCAGTGAGAG TCTGANAAAACTGTGCGTCTTTCAGAAATTTGAGAGCATTCCATTCACTGGCCCTGCCGA CTGACCATTGGCTCCATTTGTCT >OriGene 3' read for NM_021141 unedited
NTTTAGCTTGNACGCGGCCGCATCTANGATCGGTTTTTTTTTTTTTTTTTTGAGTCATTT ATGCCTTTAATGTTACATGTACAAAACTGTGTATTAGTGACGACTTATGAGGGTGCTGAA GACAGAGGTGACTGGGTACCAAGAAGTCTGTACACCAAAGAGGAACTGGAACTCAAGGCA AGAATGAGGACAAGAAAAAAAGAGAATAAGGGCTTTGTTATTTTCTTATTTAGTAAAGGA GACACCATCCACAAAGATGAAAGCTGACTTAGGTAGAAATGGGAAAGACCGAAAAGTTAC CTAAGTGTTTTAATATAACGAAACTTTCTCTCTTTGAGGCTTGCAAGTAGAGAACAGTGA AGTGATATAATTCTAACTACTGTAGTAAATTTCTCAGTTTTTGAGTTTCTAAAGGTTCAC TGATATGGCAGAGATTGGGCCAAAAGGTCTTTTCTTCATGAGACCACCACCATAACTCAC TGCTTAAAAGGAGTATGAAGGGAAATTGTGCTCCCCTTCCCACCCCACTTAAAGAAAACC ACCTATATACAGAGGCAGAGTAATGTGGTAACTAGAAGGCCTCAACTAAAAAGAGAAGTG AGTCCGTCCTTACCCATGGTTTTCCTAACCCAGCTGCTTGTTGGGAGGAAGCAAATGCTA CTGCTTGCTCAACACAAGTTGTGACAGCTGTTGGAGGATCAGGCAAAGGGAGACTCTGGA AAGGGTTAAGAAACTCATCAATAACCATGCCATGTTTCCCATGAGACACTAATTACATCA CAAGGGCTGCCACTGTCACTGATATACTACGTCAAGAAAGGACTACTTTCCAGAAACTTC AAAGCTTGTTTGTGATTTTCAAAGATCTGGTAGACCCCGAAAAAATATACCCCACCCGGA AATAACATGACTCTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_021141 |
| Insert Size | 3460 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_021141.2, NP_066964.1 |
| RefSeq Size | 3310 bp |
| RefSeq ORF | 2199 bp |
| Locus ID | 7520 |
| UniProt ID | P13010 |
| Domains | VWA, Ku_C, Ku_N, ku |
| Protein Families | Druggable Genome, Stem cell - Pluripotency |
| Protein Pathways | Non-homologous end-joining |
| Gene Summary | The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210649 | XRCC5 (Myc-DDK-tagged)-Human X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) (XRCC5) |
CNY 5,360.00 |
|
| RC210649L1 | Lenti ORF clone of Human X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) (XRCC5), Myc-DDK-tagged |
CNY 7,700.00 |
|
| RC210649L2 | Lenti ORF clone of Human X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) (XRCC5), mGFP tagged |
CNY 7,700.00 |
|
| RC210649L3 | Lenti ORF clone of Human X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) (XRCC5), Myc-DDK-tagged |
CNY 7,700.00 |
|
| RC210649L4 | Lenti ORF clone of Human X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) (XRCC5), mGFP tagged |
CNY 7,700.00 |
|
| RG210649 | XRCC5 (tGFP-tagged) - Human X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) (XRCC5) |
CNY 6,370.00 |
|
| SC321015 | XRCC5 (untagged)-Human X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) (XRCC5) |
CNY 2,950.00 |
