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ADAM12 (NM_021641) Human Untagged Clone
CAT＃: SC112913
ADAM12 (untagged)-Human ADAM metallopeptidase domain 12 (ADAM12), transcript variant 2
CNY 8,120.00
Product images
热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ADAM12-OT1; CAR10; MCMP; MCMPMltna; MLTN; MLTNA |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC112913 sequence for NM_021641 edited (data generated by NextGen Sequencing)
ATGGCAGCGCGCCCGCTGCCCGTGTCCCCCGCCCGCGCCCTCCTGCTCGCCCTGGCCGGT GCTCTGCTCGCGCCCTGCGAGGCCCGAGGGGTGAGCTTATGGAACCAAGGAAGAGCTGAT GAAGTTGTCAGTGCCTCTGTTGGGAGTGGGGACCTCTGGATCCCAGTGAAGAGCTTCGAC TCCAAGAATCATCCAGAAGTGCTGAATATTCGACTACAACGGGAAAGCAAAGAACTGATC ATAAATCTGGAAAGAAATGAAGGTCTCATTGCCAGCAGTTTCACGGAAACCCACTATCTG CAAGACGGTACTGATGTCTCCCTCGCTCGAAATTACACGGTAATTCTGGGTCACTGTTAC TACCATGGACATGTACGGGGATATTCTGATTCAGCAGTCAGTCTCAGCACGTGTTCTGGT CTCAGGGGACTTATTGTGTTTGAAAATGAAAGCTATGTCTTAGAACCAATGAAAAGTGCA ACCAACAGATACAAACTCTTCCCAGCGAAGAAGCTGAAAAGCGTCCGGGGATCATGTGGA TCACATCACAACACACCAAACCTCGCTGCAAAGAATGTGTTTCCACCACCCTCTCAGACA TGGGCAAGAAGGCATAAAAGAGAGACCCTCAAGGCAACTAAGTATGTGGAGCTGGTGATC GTGGCAGACAACCGAGAGTTTCAGAGGCAAGGAAAAGATCTGGAAAAAGTTAAGCAGCGA TTAATAGAGATTGCTAATCACGTTGACAAGTTTTACAGACCACTGAACATTCGGATCGTG TTGGTAGGCGTGGAAGTGTGGAATGACATGGACAAATGCTCTGTAAGTCAGGACCCATTC ACCAGCCTCCATGAATTTCTGGACTGGAGGAAGATGAAGCTTCTACCTCGCAAATCCCAT GACAATGCGCAGCTTGTCAGTGGGGTTTATTTCCAAGGGACCACCATCGGCATGGCCCCA ATCATGAGCATGTGCACGGCAGACCAGTCTGGGGGAATTGTCATGGACCATTCAGACAAT CCCCTTGGTGCAGCCGTGACCCTGGCACATGAGCTGGGCCACAATTTCGGGATGAATCAT GACACACTGGACAGGGGCTGTAGCTGTCAAATGGCGGTTGAGAAAGGAGGCTGCATCATG AACGCTTCCACCGGGTACCCATTTCCCATGGTGTTCAGCAGTTGCAGCAGGAAGGACTTG GAGACCAGCCTGGAGAAAGGAATGGGGGTGTGCCTGTTTAACCTGCCGGAAGTCAGGGAG TCTTTCGGGGGCCAGAAGTGTGGGAACAGATTTGTGGAAGAAGGAGAGGAGTGTGACTGT GGGGAGCCAGAGGAATGTATGAATCGCTGCTGCAATGCCACCACCTGTACCCTGAAGCCG GACGCTGTGTGCGCACATGGGCTGTGCTGTGAAGACTGCCAGCTGAAGCCTGCAGGAACA GCGTGCAGGGACTCCAGCAACTCCTGTGACCTCCCAGAGTTCTGCACAGGGGCCAGCCCT CACTGCCCAGCCAACGTGTACCTGCACGATGGGCACTCATGTCAGGATGTGGACGGCTAC TGCTACAATGGCATCTGCCAGACTCACGAGCAGCAGTGTGTCACGCTCTGGGGACCAGGT GCTAAACCTGCCCCTGGGATCTGCTTTGAGAGAGTCAATTCTGCAGGTGATCCTTATGGC AACTGTGGCAAAGTCTCGAAGAGTTCCTTTGCCAAATGCGAGATGAGAGATGCTAAATGT GGAAAAATCCAGTGTCAAGGAGGTGCCAGCCGGCCAGTCATTGGTACCAATGCCGTTTCC ATAGAAACAAACATCCCCCTGCAGCAAGGAGGCCGGATTCTGTGCCGGGGGACCCACGTG TACTTGGGCGATGACATGCCGGACCCAGGGCTTGTGCTTGCAGGCACAAAGTGTGCAGAT GGAAAAATCTGCCTGAATCGTCAATGTCAAAATATTAGTGTCTTTGGGGTTCACGAGTGT GCAATGCAGTGCCACGGCAGAGGGGTGTGCAACAACAGGAAGAACTGCCACTGCGAGGCC CACTGGGCACCTCCCTTCTGTGACAAGTTTGGCTTTGGAGGAAGCACAGACAGCGGCCCC ATCCGGCAAGCAGAAGCAAGGCAGGAAGCTGCAGAGTCCAACAGGGAGCGCGGCCAGGGC CAGGAGCCCGTGGGATCGCAGGAGCATGCATCTACTGCCTCACTGACACTCATCTGA Clone variation with respect to NM_021641.3 2190 g=>a >OriGene 5' read for NM_021641 unedited
CGTTCACATTTGTATACGACTCCTATAGGGCGGCCGCGAATTCGCACCAGGCTCTTCCTA GTCCCCGGGCCAACTCGGACAGTTTGCTCATTTATTGCAACGGTCAAGGCTGGCTTGTGC CAGAACGGCGCGCGCGCGCGCACGCACGCACACACACGGGGGGAAACTTTTTTAAAAATG AAAGGCTAGAAGAGCTCAGCGGCGGCGCGGGCGCTGCGCGAGGGCTCCGGAGCTGACTCG CCGAGGCAGGAAATCCCTCCGGTCGCGACGCCCGGCCCCGGCTCGGCGCCCGCGTGGGAT GGTGCAGCGCTCGCCGCCGGGCCCGAGAGCTGCTGCACTGAAGGCCGGCGACGATGGCAG CGCGCCCGCTGCCCGTGTCCCCCGCCCGCGCCCTCCTGCTCGCCCTGGCCGGTGCTCTGC TCGCGCCCTGCGAGGCCCGAGGGGTGAGCTTATGGAACCAAGGAAGAGCTGATGAAGTTG TCAGTGCCTCTGTTGGGAGTGGGGACCTCTGGATCCCAGTGAAGAGCTTCGACTCCAAGA ATCATCCAGAAGTGCTGAATATTCGACTACAACGGGAAAGCAAAGAACTGATCATAAATC TGGAAAGAAATGAAGGTCTCATTGCCAGCAGTTTCACGGAAACCCACTATCTGCAAGACG GTACTGATGTCTCCCTCGCTCGAAATACACGGGTATTCTGGGTCACTGTTACTACCATGG ACATGTACGGNGATATTCTGATTCAGCAGTCAGTCTCAGCACGTGTTCTGGTCTCAGGNG ACTTATTGTGTTTGAAAATGAAAGCTATGNTCTTANACCNATGGAAANGTGCACCCAACA GATACAACTCTTTCCAGCGAAAGAGCTGAANAGCGTCCGGGGGTCATGTTGGTCACATTA CAACACACAAAACT >OriGene 3' read for NM_021641 unedited
AATGGAAATACTGTGNACCGCGCCCTAGCTATGATCNATTTTTCTTTTTTTTTTTTATTT CAAATGCACTCTATTTTATGCAGTAATGGCCACGGGGGATGGAGTTAGGCTCTTACATTG TTTTCACTTTTTAACATTCTTACTTGTTAAATGAAGGGTTGGTGACTCTGTGGGTTCCCT GGCTTTCTGCAAACCCTCAAACCTGAGTACTGTTTTTCACGCATGTCCACAGCAAAGAGC CAGAGTTCACCGCCCTTTCTCCTACCTTCTTCTCCAGTTTGTTTCAATGCCATTCAGTTT GCTTGGATGGAGATGGAATGGGTGGCAGGGTCTCTGATAAATTAAAAACTAAAACCCTGC TATTTTCATATAATAAATGCTAAAAGCCATATCAGAGCATTAAGTTGCAGCCAGAGACCA GTCATCAGGGCTGCCAAGGCTGAAGTGTCACTGGGGAAAGGGGACACTGGGCCCAACCCT TGCTTCTCCCCCACTGCTGTGGGGGCTCATTGAAAGGCCAGACTTTTGAGTCCTCTTCCT CCTTGCTGCAGGGCTGGGGCCTGCCAGAGTGGTAACCTGCTACTCTCTCAAGGGCAGCCC TGAAGCATGTCCATGTTTTAGCAGAAGCTCATCCTGGAAGACGCTGCACTACCTTGCCCT GTTTTTGCAGACGTGCCTGGTACGCTGCACTTTCCCTCCTGAAAGCCCAAAAACTGACAT AAGTCCTGATGTCATGGAAAACCACGGGCCAGGCCCCCAGCCGCAGGCACGTGACCCAAC AGAGGGCCACAGGAAACAAAAGGACCATAATTAGATAACCTAATATCTACAAGGACTACC GAATTAATGGGGAAGGCCTACAATATAACAGGTAAGCACTTACACAGAAGTGTGGCCGGC A |
| Restriction Sites | NotI-NotI |
| ACCN | NM_021641 |
| Insert Size | 3750 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_021641.2, NP_067673.2 |
| RefSeq Size | 3355 bp |
| RefSeq ORF | 2217 bp |
| Locus ID | 8038 |
| UniProt ID | O43184 |
| Protein Families | Druggable Genome, Protease, Secreted Protein, Transmembrane |
| Gene Summary | This gene encodes a member of a family of proteins that are structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Expression of this gene has been used as a maternal serum marker for pre-natal development. Alternative splicing results in multiple transcript variants encoding different isoforms. Shorter isoforms are secreted, while longer isoforms are membrane-bound form. [provided by RefSeq, Jan 2014] Transcript Variant: This variant (2) lacks multiple 3' coding exons and contains an alternate 3' terminal exon, resulting in a different 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (2, also known as ADAM12-S) has a distinct C-terminus and is shorter than isoform 1. |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC222280 | ADAM12 (Myc-DDK-tagged)-Human ADAM metallopeptidase domain 12 (ADAM12), transcript variant 2 |
CNY 7,320.00 |
|
| RC222280L3 | Lenti-ORF clone of ADAM12 (Myc-DDK-tagged)-Human ADAM metallopeptidase domain 12 (ADAM12), transcript variant 2 |
CNY 9,220.00 |
|
| RC222280L4 | Lenti-ORF clone of ADAM12 (mGFP-tagged)-Human ADAM metallopeptidase domain 12 (ADAM12), transcript variant 2 |
CNY 9,220.00 |
|
| RG222280 | ADAM12 (tGFP-tagged) - Human ADAM metallopeptidase domain 12 (ADAM12), transcript variant 2 |
CNY 10,248.00 |
