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CYP1B1 (NM_000104) Human Untagged Clone
CAT＃: SC103335
CYP1B1 (untagged)-Human cytochrome P450, family 1, subfamily B, polypeptide 1 (CYP1B1)
CNY 6,072.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ASGD6; CP1B; CYPIB1; GLC3A; P4501B1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC103335 sequence for NM_000104 edited (data generated by NextGen Sequencing)
ATGGGCACCAGCCTCAGCCCGAACGACCCTTGGCCGCTAAACCCGCTGTCCATCCAGCAG ACCACGCTCCTGCTACTCCTGTCGGTGCTGGCCACTGTGCATGTGGGCCAGCGGCTGCTG AGGCAACGGAGGCGGCAGCTCGGGTCCGCGCCCCCGGGCCCGTTTGCGTGGCCACTGATC GGAAACGCGGCGGCGGTGGGCCAGGCGGCTCACCTCTCGTTCGCTCGCCTGGCGCGGCGC TACGGCGACGTTTTCCAGATCCGCCTGGGCAGCTGCCCCATAGTGGTGCTGAATGGCGAG CGCGCCATCCACCAGGCCCTGGTGCAGCAGGGCTCGGCCTTCGCCGACCGGCCGTCCTTC GCCTCCTTCCGTGTGGTGTCCGGCGGCCGCAGCATGGCTTTCGGCCACTACTCGGAGCAC TGGAAGGTGCAGCGGCGCGCAGCCCACAGCATGATGCGCAACTTCTTCACGCGCCAGCCG CGCAGCCGCCAAGTCCTCGAGGGCCACGTGCTGAGCGAGGCGCGCGAGCTGGTGGCGCTG CTGGTGCGCGGCAGCGCGGACGGCGCCTTCCTCGACCCGAGGCCGCTGACCGTCGTGGCC GTGGCCAACGTCATGAGTGCCGTGTGTTTCGGCTGCCGCTACAGCCACGACGACCCCGAG TTCCGTGAGCTGCTCAGCCACAACGAAGAGTTCGGGCGCACGGTGGGCGCGGGCAGCCTG GTGGACGTGATGCCCTGGCTGCAGTACTTCCCCAACCCGGTGCGCACCGTTTTCCGCGAA TTCGAGCAGCTCAACCGCAACTTCAGCAACTTCATCCTGGACAAGTTCTTGAGGCACTGC GAAAGCCTTCGGCCCGGGGCCGCCCCCCGCGACATGATGGACGCCTTTATCCTCTCTGCG GAAAAGAAGGCGGCCGGGGACTCGCACGGTGGTGGCGCGCGGCTGGATTTGGAGAACGTA CCGGCCACTATCACTGACATCTTCGGCGCCAGCCAGGACACCCTGTCCACCGCGCTGCAG TGGCTGCTCCTCCTCTTCACCAGGTATCCTGATGTGCAGACTCGAGTGCAGGCAGAATTG GATCAGGTCGTGGGGAGGGACCGTCTGCCTTGTATGGGTGACCAGCCCAACCTGCCCTAT GTCCTGGCCTTCCTTTATGAAGCCATGCGCTTCTCCAGCTTTGTGCCTGTCACTATTCCT CATGCCACCACTGCCAACACCTCTGTCTTGGGCTACCACATTCCCAAGGACACTGTGGTT TTTGTCAACCAGTGGTCTGTGAATCATGACCCACTGAAGTGGCCTAACCCGGAGAACTTT GATCCAGCTCGATTCTTGGACAAGGACGGCCTCATCAACAAGGACCTGACCAGCAGAGTG ATGATTTTTTCAGTGGGCAAAAGGCGGTGCATTGGCGAAGAACTTTCTAAGATGCAGCTT TTTCTCTTCATCTCCATCCTGGCTCACCAGTGCGATTTCAGGGCCAACCCAAATGAGCCT GCGAAAATGAATTTCAGTTATGGTCTAACCATTAAACCCAAGTCATTTAAAGTCAATGTC ACTCTCAGAGAGTCCATGGAGCTCCTTGATAGTGCTGTCCAAAATTTACAAGCCAAGGAA ACTTGCCAATAA Clone variation with respect to NM_000104.3 142 c=>g;355 g=>t;1347 t=>c >OriGene 5' read for NM_000104 unedited
CTCCGTTTGTAACCGACTTTCTATAGGCGGCCGACGAATTCGCACGAGGTGGGAGCGAGC GCTTCTGCGACTCCGTTGTGAGAGCCGCAGGGCATGGGAATTGACGCCACTCACCGACCC CCAGTCTCAATCTCAACGCTGTGAGGAAACCTCGACTTTGCCAGGTCCCCAAGGGCAGCG GGGCTCGGCGAGCGAGGCACCCTTCTCCGTCCCCATCCCAATCCAAGCGCTCCTGGCACT GACGACGCCAAGAGACTCGAGTGGGAGTTAAAGCTTCCAGTGAGGGCAGCAGGTGTCCAG GCCGGGCCTGCGGGTTCCTGTTGACGTCTTGCCCTATGCAAAGGTCCCAGTTCCTTCTCG GAGCCGGCTGTCCCGCGCCACTGGAAACCGCACCTCCCCGCAGCATGGGCACCAGCCTCA GCCCGAACGACCCTTGGCCGCTAAACCCGCTGTCCATCCAGCAGACCACGCTCCTGCTAC TCCTGTCGGTGCTGGCCACTGTGCATGTGGGCCAGCGGCTGCTGAGGCAACGGATGCGGC AGCTCGGGTCCGCGCCCCCGGGCCCGTTTGCGTGGCCACTGATCGGAAACGCGGCGGCGG TGGGCCAGGCGGCTCACCTCTCGTTCGCTCGCCTGGCGCGGCGCTACGGCGACGTTTTCC AGATCCGCCTGGGCAGCTGCCCCATAGTGGTGCTGAATGGCGAGCGCGCCATCCACCATG CCCTGGTGCAGCATGGCTCGGCCTTCGCCGACCGGCCGTCCTTCGCCTCCTTCCGTGTGG TGTCCGGCAGCCGCAGCATGGCTTTCGGCCACTACTCNGAGCACTGGAANGTGCAGCGGC GCGCATCCCACACATGATGCGCAACTTCTTCACGCGCCAGCCGCGCATCCGCAAGTCCTC GAGGCCACGTGCTGACCA >OriGene 3' read for NM_000104 unedited
CGGCCGCAATCTAGAATCGAGTTTTTTTTTTTTTTTTTTGCTGATAATTCAAATTCTGTA CTTTGGCAAGCAAAAGAGGTACAACATCACCTTGGAGTTTTACAATTTAATAATGCATAC TTTAAAATTCATGATAAATCATGGAACCCCACTATACTCACTAATTCAACTATTGATTTC TTTTTGAGCAACTGACTTTATGATTTATCCTTAAAAGTAAGGAAGTATACCAGAAGGCAA AAGGATAAATCCACCCATAAATACTAGAGTCTAAGTTATTTTCCTGAAAAGGTGAAAAGG GAATTTCTGGTCTTTATCTTTTCCCTTATCACCTTCAATCACACACTTTACACTGAAATT ACTTGTCTCTGTCTCTTCAACAATATACTCTGAAACTTTGTTTAATATACTTTTTGTCTA TTTCTGCATATGGGAGACCAATCTTGGATTCCCACCAAAAATGGCCTGGTTACCAAAATA CTTCTTCATTCAGTAGTTTGGTGTAAGTGTTTGGGTGTATGTGTCTATATGTGCATTTTA ACTCCAAAGAATGCTACCTTCAGAAATAACCAAGATGCAGTATGTATATAATAATTCATT GGGCCCTTTAAGTCTTTGACTCAAAAAAAATCTCCCAGAAGCTCCTGCATAGCCCACTAC TCATGAAGAACCGCTGGGTATGGAGCACACCTCACCTGATGGACAGTTGATTTATGCTCA CCTCTAACGCNTATTGAGAAGCAGCACANAAGAAGAACTGGAAAAAACTGAATTTTACTC CTCATCTCCGAAGATGTGATATTNTCTAAATTNNCAGCTGCCTCTTGCTTCTATAGGCAA GTTCCTTGGCTGNAAATTTGAACAGACTATCAGAGCTCATGGACTTCTGANATGACATGA CTTAAATGACTGGTNAATGGTAAACATACTGNATCATTTTCCAGCTCATTGGGTGGCCTG AATCCN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000104 |
| Insert Size | 2880 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000104.2, NP_000095.1 |
| RefSeq Size | 5128 bp |
| RefSeq ORF | 1632 bp |
| Locus ID | 1545 |
| UniProt ID | Q16678 |
| Domains | p450 |
| Protein Families | Druggable Genome, P450 |
| Protein Pathways | Metabolism of xenobiotics by cytochrome P450, Tryptophan metabolism |
| Gene Summary | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid. [provided by RefSeq, Jul 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
HDAC6 modulates HSP90 chaperone activity and regulates activation of aryl hydrocarbon receptor signaling
,Vikram D. Kekatpure, Andrew J. Dannenberg, and Kotha Subbaramaiah,
J. Biol. Chem., Jan 2009; 10.1074/jbc.M808999200.
[CYP1B1]
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