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NMDAR2C (GRIN2C) (NM_001278553) Human Tagged ORF Clone
CAT＃: RG239716
- TrueORF®
GRIN2C (tGFP-tagged) - Human glutamate receptor, ionotropic, N-methyl D-aspartate 2C (GRIN2C), transcript variant 2
ORF Plasmid: DDK
"NM_001278553" in other vectors (2)
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CNY 7,510.00
Product images
Specifications
| Product Data | |
| Tag | TurboGFP |
| Synonyms | GluN2C; NMDAR2C; NR2C |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG239716 representing NM_001278553.
Blue=ORF Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGGTGGGGCCCTGGGGCCGGCCCTGTTGCTCACCTCGCTCTTCGGTGCCTGGGCAGGGCTGGGTCCG GGGCAGGGCGAGCAGGGCATGACGGTGGCCGTGGTGTTTAGCAGCTCAGGGCCGCCCCAGGCCCAGTTC CGTGCCCGCCTCACCCCCCAGAGCTTCCTGGACCTACCCCTGGAGATCCAGCCGCTCACAGTTGGGGTC AACACCACCAACCCCAGCAGCCTCCTCACCCAGATCTGCGGCCTCCTGGGTGCTGCCCACGTCCACGGC ATTGTCTTTGAGGACAACGTGGACACCGAGGCGGTGGCCCAGATCCTTGACTTCATCTCCTCCCAGACC CATGTGCCCATCCTCAGCATCAGCGGAGGCTCTGCTGTGGTCCTCACCCCCAAGGAGCCGGGCTCCGCC TTCCTGCAGCTGGGCGTGTCCCTGGAGCAGCAGCTGCAGGTGCTGTTCAAGGTGCTGGAAGAGTACGAC TGGAGCGCCTTCGCCGTCATCACCAGCCTGCACCCGGGCCACGCGCTCTTCCTGGAGGGCGTGCGCGCC GTCGCCGACGCCAGCCACGTGAGTTGGCGGCTGCTGGACGTGGTCACGCTGGAGCTGGGCCCGGGAGGG CCGCGCGCGCGCACGCAGCGCCTGCTGCGCCAGCTCGACGCGCCCGTGTTTGTGGCCTACTGCTCGCGC GAGGAGGCCGAGGTGCTCTTCGCCGAGGCGGCGCAGGCCGGTCTGGTGGGGCCCGGCCACGTGTGGCTG GTGCCCAACCTGGCGCTGGGCAGCACCGATGCGCCCCCCGCCACCTTCCCCGTGGGCCTCATCAGCGTC GTCACCGAGAGCTGGCGCCTCAGCCTGCGCCAGAAGGTGCGCGACGGCGTGGCCATTCTGGCCCTGGGC GCCCACAGCTACTGGCGCCAGCATGGAACCCTGCCAGCCCCGGCCGGGGACTGCCGTGTTCACCCTGGG CCCGTCAGCCCTGCCCGGGAGGCCTTCTACAGGCACCTACTGAATGTCACCTGGGAGGGCCGAGACTTC TCCTTCAGCCCTGGTGGGTACCTGGTCCAGCCCACCATGGTGGTGATCGCCCTCAACCGGCACCGCCTC TGGGAGATGGTGGGGCGCTGGGAGCATGGCGTCCTATACATGAAGTACCCCGTGTGGCCTCGCTACAGT GCCTCTCTGCAGCCTGTGGTGGACAGTCGGCACCTGACGGTGGCCACGCTGGAAGAGCGGCCCTTTGTC ATCGTGGAGAGCCCTGACCCTGGCACAGGAGGCTGTGTCCCCAACACCGTGCCCTGCCGCAGGCAGAGC AACCACACCTTCAGCAGCGGGGACGTGGCCCCCTACACCAAGCTCTGCTGTAAGGGATTCTGCATCGAC ATCCTCAAGAAGCTGGCCAGAGTGGTCAAATTCTCCTACGACCTGTACCTGGTGACCAACGGCAAGCAT GGCAAGCGGGTGCGCGGCGTATGGAACGGCATGATTGGGGAGGTGTACTACAAGCGGGCAGACATGGCC ATCGGCTCCCTCACCATCAATGAGGAACGCTCCGAGATCGTAGACTTCTCTGTACCCTTTGTGGAGACG GGCATCAGTGTGATGGTGGCTCGCAGCAATGGCACCGTCTCCCCCTCGGCCTTCTTGGAGCCATATAGC CCTGCAGTGTGGGTGATGATGTTTGTCATGTGCCTCACTGTGGTGGCCATCACCGTCTTCATGTTCGAG TACTTCAGCCCTGTCAGCTACAACCAGAACCTCACCAGAGGCAAGAAGTCCGGGGGCCCAGCTTTCACT ATCGGCAAGTCCGTGTGGCTGCTGTGGGCGCTGGTCTTCAACAACTCAGTGCCCATCGAGAACCCGCGG GGCACCACCAGCAAGATCATGGTTCTGGTCTGGGCCTTCTTTGCTGTCATCTTCCTCGCCAGCTACACG GCCAACCTGGCCGCCTTCATGATCCAAGAGCAATACATCGACACTGTGTCGGGCCTCAGTGACAAGAAG TTTCAGCGGCCTCAAGATCAGTACCCACCTTTCCGCTTCGGCACGGTGCCCAACGGCAGCACGGAGCGG AACATCCGCAGTAACTACCGTGACATGCACACCCACATGGTCAAGTTCAACCAGCGCTCGGTGGAGGAC GCGCTCACCAGCCTCAAGATGGGGAAGCTGGATGCCTTCATCTATGATGCTGCTGTCCTCAACTACATG GCAGGCAAGGACGAGGGCTGCAAGCTGGTCACCATTGGGTCTGGCAAGGTCTTTGCTACCACTGGCTAC GGCATCGCCATGCAGAAGGACTCCCACTGGAAGCGGGCCATAGACCTGGCGCTCTTGCAGTTCCTGGGG GACGGAGAGACACAGAAACTGGAGACAGTGTGGCTCTCAGGGATCTGCCAGAATGAGAAGAACGAGGTG ATGAGCAGCAAGCTGGACATCGACAACATGGCAGGCGTCTTCTACATGCTGCTGGTGGCCATGGGGCTG GCCCTGCTGGTCTTCGCCTGGGAGCACCTGGTCTACTGGAAGCTGCGCCACTCGGTGCCCAACTCATCC CAGCTGGACTTCCTGCTGGCTTTCAGCAGGGTGGGTGCCCACCCCTCCCCACACAGGCCAAAGTTT ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC >Peptide sequence encoded by RG239716
Blue=ORF Red=Cloning site Green=Tag(s) MGGALGPALLLTSLFGAWAGLGPGQGEQGMTVAVVFSSSGPPQAQFRARLTPQSFLDLPLEIQPLTVGV NTTNPSSLLTQICGLLGAAHVHGIVFEDNVDTEAVAQILDFISSQTHVPILSISGGSAVVLTPKEPGSA FLQLGVSLEQQLQVLFKVLEEYDWSAFAVITSLHPGHALFLEGVRAVADASHVSWRLLDVVTLELGPGG PRARTQRLLRQLDAPVFVAYCSREEAEVLFAEAAQAGLVGPGHVWLVPNLALGSTDAPPATFPVGLISV VTESWRLSLRQKVRDGVAILALGAHSYWRQHGTLPAPAGDCRVHPGPVSPAREAFYRHLLNVTWEGRDF SFSPGGYLVQPTMVVIALNRHRLWEMVGRWEHGVLYMKYPVWPRYSASLQPVVDSRHLTVATLEERPFV IVESPDPGTGGCVPNTVPCRRQSNHTFSSGDVAPYTKLCCKGFCIDILKKLARVVKFSYDLYLVTNGKH GKRVRGVWNGMIGEVYYKRADMAIGSLTINEERSEIVDFSVPFVETGISVMVARSNGTVSPSAFLEPYS PAVWVMMFVMCLTVVAITVFMFEYFSPVSYNQNLTRGKKSGGPAFTIGKSVWLLWALVFNNSVPIENPR GTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEQYIDTVSGLSDKKFQRPQDQYPPFRFGTVPNGSTER NIRSNYRDMHTHMVKFNQRSVEDALTSLKMGKLDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGY GIAMQKDSHWKRAIDLALLQFLGDGETQKLETVWLSGICQNEKNEVMSSKLDIDNMAGVFYMLLVAMGL ALLVFAWEHLVYWKLRHSVPNSSQLDFLLAFSRVGAHPSPHRPKF TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001278553 |
| ORF Size | 2619 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reference Data | |
| RefSeq | NM_001278553.1, NP_001265482.1 |
| RefSeq Size | 3269 bp |
| RefSeq ORF | 2622 bp |
| Locus ID | 2905 |
| Protein Families | Druggable Genome, Ion Channels: Glutamate Receptors, Transmembrane |
| Protein Pathways | Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Calcium signaling pathway, Long-term potentiation, Neuroactive ligand-receptor interaction |
| MW | 96.4 kDa |
| Gene Summary | This gene encodes a subunit of the N-methyl-D-aspartate (NMDA) receptor, which is a subtype of ionotropic glutamate receptor. NMDA receptors are found in the central nervous system, are permeable to cations and have an important role in physiological processes such as learning, memory, and synaptic development. The receptor is a tetramer of different subunits (typically heterodimer of subunit 1 with one or more of subunits 2A-D), forming a channel that is permeable to calcium, potassium, and sodium, and whose properties are determined by subunit composition. Alterations in the subunit composition of the receptor are associated with pathophysiological conditions such as Parkinson's disease, Alzheimer's disease, depression, and schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC239716 | GRIN2C (myc-DDK-tagged) - Human glutamate receptor, ionotropic, N-methyl D-aspartate 2C (GRIN2C), transcript variant 2 |
CNY 7,130.00 |
|
| SC337610 | GRIN2C (untagged) - Human glutamate receptor, ionotropic, N-methyl D-aspartate 2C (GRIN2C), transcript variant 2 |
CNY 8,460.00 |
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