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MRP5 (ABCC5) (NM_005688) Human Tagged ORF Clone
CAT＃: RC224017
- TrueORF®
ABCC5 (Myc-DDK-tagged)-Human ATP-binding cassette, sub-family C (CFTR/MRP), member 5 (ABCC5), transcript variant 1
ORF Plasmid: tGFP
"NM_005688" in other vectors (6)
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CNY 14,744.00
Product images
CNY 300.00
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | ABC33; EST277145; MOAT-C; MOATC; MRP5; pABC11; SMRP |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC224017 representing NM_005688
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAAGGATATCGACATAGGAAAAGAGTATATCATCCCCAGTCCTGGGTATAGAAGTGTGAGGGAGAGAA CCAGCACTTCTGGGACGCACAGAGACCGTGAAGATTCCAAGTTCAGGAGAACTCGACCGTTGGAATGCCA AGATGCCTTGGAAACAGCAGCCCGAGCCGAGGGCCTCTCTCTTGATGCCTCCATGCATTCTCAGCTCAGA ATCCTGGATGAGGAGCATCCCAAGGGAAAGTACCATCATGGCTTGAGTGCTCTGAAGCCCATCCGGACTA CTTCCAAACACCAGCACCCAGTGGACAATGCTGGGCTTTTTTCCTGTATGACTTTTTCGTGGCTTTCTTC TCTGGCCCGTGTGGCCCACAAGAAGGGGGAGCTCTCAATGGAAGACGTGTGGTCTCTGTCCAAGCACGAG TCTTCTGACGTGAACTGCAGAAGACTAGAGAGACTGTGGCAAGAAGAGCTGAATGAAGTTGGGCCAGACG CTGCTTCCCTGCGAAGGGTTGTGTGGATCTTCTGCCGCACCAGGCTCATCCTGTCCATCGTGTGCCTGAT GATCACGCAGCTGGCTGGCTTCAGTGGACCAGCCTTCATGGTGAAACACCTCTTGGAGTATACCCAGGCA ACAGAGTCTAACCTGCAGTACAGCTTGTTGTTAGTGCTGGGCCTCCTCCTGACGGAAATCGTGCGGTCTT GGTCGCTTGCACTGACTTGGGCATTGAATTACCGAACCGGTGTCCGCTTGCGGGGGGCCATCCTAACCAT GGCATTTAAGAAGATCCTTAAGTTAAAGAACATTAAAGAGAAATCCCTGGGTGAGCTCATCAACATTTGC TCCAACGATGGGCAGAGAATGTTTGAGGCAGCAGCCGTTGGCAGCCTGCTGGCTGGAGGACCCGTTGTTG CCATCTTAGGCATGATTTATAATGTAATTATTCTGGGACCAACAGGCTTCCTGGGATCAGCTGTTTTTAT CCTCTTTTACCCAGCAATGATGTTTGCATCACGGCTCACAGCATATTTCAGGAGAAAATGCGTGGCCGCC ACGGATGAACGTGTCCAGAAGATGAATGAAGTTCTTACTTACATTAAATTTATCAAAATGTATGCCTGGG TCAAAGCATTTTCTCAGAGTGTTCAAAAAATCCGCGAGGAGGAGCGTCGGATATTGGAAAAAGCTGGGTA CTTCCAGAGCATCACTGTGGGTGTGGCTCCCATTGTGGTGGTGATTGCCAGCGTGGTGACCTTCTCTGTT CATATGACCCTGGGCTTCGATCTGACAGCAGCACAGGCTTTCACAGTGGTGACAGTCTTCAATTCCATGA CTTTTGCTTTGAAAGTAACACCGTTTTCAGTAAAGTCCCTCTCAGAAGCCTCAGTGGCTGTTGACAGATT TAAGAGTTTGTTTCTAATGGAAGAGGTTCACATGATAAAGAACAAACCAGCCAGTCCTCACATCAAGATA GAGATGAAAAATGCCACCTTGGCATGGGACTCCTCCCACTCCAGTATCCAGAACTCGCCCAAGCTGACCC CCAAAATGAAAAAAGACAAGAGGGCTTCCAGGGGCAAGAAAGAGAAGGTGAGGCAGCTGCAGCGCACTGA GCATCAGGCGGTGCTGGCAGAGCAGAAAGGCCACCTCCTCCTGGACAGTGACGAGCGGCCCAGTCCCGAA GAGGAAGAAGGCAAGCACATCCACCTGGGCCACCTGCGCTTACAGAGGACACTGCACAGCATCGATCTGG AGATCCAAGAGGGTAAACTGGTTGGAATCTGTGGCAGTGTGGGAAGTGGAAAAACCTCTCTCATTTCAGC CATTTTAGGCCAGATGACGCTTCTAGAGGGCAGCATTGCAATCAGTGGAACCTTCGCTTATGTGGCCCAG CAGGCCTGGATCCTCAATGCTACTCTGAGAGACAACATCCTGTTTGGGAAGGAATATGATGAAGAAAGAT ACAACTCTGTGCTGAACAGCTGCTGCCTGAGGCCTGACCTGGCCATTCTTCCCAGCAGCGACCTGACGGA GATTGGAGAGCGAGGAGCCAACCTGAGCGGTGGGCAGCGCCAGAGGATCAGCCTTGCCCGGGCCTTGTAT AGTGACAGGAGCATCTACATCCTGGACGACCCCCTCAGTGCCTTAGATGCCCATGTGGGCAACCACATCT TCAATAGTGCTATCCGGAAACATCTCAAGTCCAAGACAGTTCTGTTTGTTACCCACCAGTTACAGTACCT GGTTGACTGTGATGAAGTGATCTTCATGAAAGAGGGCTGTATTACGGAAAGAGGCACCCATGAGGAACTG ATGAATTTAAATGGTGACTATGCTACCATTTTTAATAACCTGTTGCTGGGAGAGACACCGCCAGTTGAGA TCAATTCAAAAAAGGAAACCAGTGGTTCACAGAAGAAGTCACAAGACAAGGGTCCTAAAACAGGATCAGT AAAGAAGGAAAAAGCAGTAAAGCCAGAGGAAGGGCAGCTTGTGCAGCTGGAAGAGAAAGGGCAGGGTTCA GTGCCCTGGTCAGTATATGGTGTCTACATCCAGGCTGCTGGGGGCCCCTTGGCATTCCTGGTTATTATGG CCCTTTTCATGCTGAATGTAGGCAGCACCGCCTTCAGCACCTGGTGGTTGAGTTACTGGATCAAGCAAGG AAGCGGGAACACCACTGTGACTCGAGGGAACGAGACCTCGGTGAGTGACAGCATGAAGGACAATCCTCAT ATGCAGTACTATGCCAGCATCTACGCCCTCTCCATGGCAGTCATGCTGATCCTGAAAGCCATTCGAGGAG TTGTCTTTGTCAAGGGCACGCTGCGAGCTTCCTCCCGGCTGCATGACGAGCTTTTCCGAAGGATCCTTCG AAGCCCTATGAAGTTTTTTGACACGACCCCCACAGGGAGGATTCTCAACAGGTTTTCCAAAGACATGGAT GAAGTTGACGTGCGGCTGCCGTTCCAGGCCGAGATGTTCATCCAGAACGTTATCCTGGTGTTCTTCTGTG TGGGAATGATCGCAGGAGTCTTCCCGTGGTTCCTTGTGGCAGTGGGGCCCCTTGTCATCCTCTTTTCAGT CCTGCACATTGTCTCCAGGGTCCTGATTCGGGAGCTGAAGCGTCTGGACAATATCACGCAGTCACCTTTC CTCTCCCACATCACGTCCAGCATACAGGGCCTTGCCACCATCCACGCCTACAATAAAGGGCAGGAGTTTC TGCACAGATACCAGGAGCTGCTGGATGACAACCAAGCTCCTTTTTTTTTGTTTACGTGTGCGATGCGGTG GCTGGCTGTGCGGCTGGACCTCATCAGCATCGCCCTCATCACCACCACGGGGCTGATGATCGTTCTTATG CACGGGCAGATTCCCCCAGCCTATGCGGGTCTCGCCATCTCTTATGCTGTCCAGTTAACGGGGCTGTTCC AGTTTACGGTCAGACTGGCATCTGAGACAGAAGCTCGATTCACCTCGGTGGAGAGGATCAATCACTACAT TAAGACTCTGTCCTTGGAAGCACCTGCCAGAATTAAGAACAAGGCTCCCTCCCCTGACTGGCCCCAGGAG GGAGAGGTGACCTTTGAGAACGCAGAGATGAGGTACCGAGAAAACCTCCCTCTCGTCCTAAAGAAAGTAT CCTTCACGATCAAACCTAAAGAGAAGATTGGCATTGTGGGGCGGACAGGATCAGGGAAGTCCTCGCTGGG GATGGCCCTCTTCCGTCTGGTGGAGTTATCTGGAGGCTGCATCAAGATTGATGGAGTGAGAATCAGTGAT ATTGGCCTTGCCGACCTCCGAAGCAAACTCTCTATCATTCCTCAAGAGCCGGTGCTGTTCAGTGGCACTG TCAGATCAAATTTGGACCCCTTCAACCAGTACACTGAAGACCAGATTTGGGATGCCCTGGAGAGGACACA CATGAAAGAATGTATTGCTCAGCTACCTCTGAAACTTGAATCTGAAGTGATGGAGAATGGGGATAACTTC TCAGTGGGGGAACGGCAGCTCTTGTGCATAGCTAGAGCCCTGCTCCGCCACTGTAAGATTCTGATTTTAG ATGAAGCCACAGCTGCCATGGACACAGAGACAGACTTATTGATTCAAGAGACCATCCGAGAAGCATTTGC AGACTGTACCATGCTGACCATTGCCCATCGCCTGCACACGGTTCTAGGCTCCGATAGGATTATGGTGCTG GCCCAGGGACAGGTGGTGGAGTTTGACACCCCATCGGTCCTTCTGTCCAACGACAGTTCCCGATTCTATG CCATGTTTGCTGCTGCAGAGAACAAGGTCGCTGTCAAGGGC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC224017 representing NM_005688
Red=Cloning site Green=Tags(s) MKDIDIGKEYIIPSPGYRSVRERTSTSGTHRDREDSKFRRTRPLECQDALETAARAEGLSLDASMHSQLR ILDEEHPKGKYHHGLSALKPIRTTSKHQHPVDNAGLFSCMTFSWLSSLARVAHKKGELSMEDVWSLSKHE SSDVNCRRLERLWQEELNEVGPDAASLRRVVWIFCRTRLILSIVCLMITQLAGFSGPAFMVKHLLEYTQA TESNLQYSLLLVLGLLLTEIVRSWSLALTWALNYRTGVRLRGAILTMAFKKILKLKNIKEKSLGELINIC SNDGQRMFEAAAVGSLLAGGPVVAILGMIYNVIILGPTGFLGSAVFILFYPAMMFASRLTAYFRRKCVAA TDERVQKMNEVLTYIKFIKMYAWVKAFSQSVQKIREEERRILEKAGYFQSITVGVAPIVVVIASVVTFSV HMTLGFDLTAAQAFTVVTVFNSMTFALKVTPFSVKSLSEASVAVDRFKSLFLMEEVHMIKNKPASPHIKI EMKNATLAWDSSHSSIQNSPKLTPKMKKDKRASRGKKEKVRQLQRTEHQAVLAEQKGHLLLDSDERPSPE EEEGKHIHLGHLRLQRTLHSIDLEIQEGKLVGICGSVGSGKTSLISAILGQMTLLEGSIAISGTFAYVAQ QAWILNATLRDNILFGKEYDEERYNSVLNSCCLRPDLAILPSSDLTEIGERGANLSGGQRQRISLARALY SDRSIYILDDPLSALDAHVGNHIFNSAIRKHLKSKTVLFVTHQLQYLVDCDEVIFMKEGCITERGTHEEL MNLNGDYATIFNNLLLGETPPVEINSKKETSGSQKKSQDKGPKTGSVKKEKAVKPEEGQLVQLEEKGQGS VPWSVYGVYIQAAGGPLAFLVIMALFMLNVGSTAFSTWWLSYWIKQGSGNTTVTRGNETSVSDSMKDNPH MQYYASIYALSMAVMLILKAIRGVVFVKGTLRASSRLHDELFRRILRSPMKFFDTTPTGRILNRFSKDMD EVDVRLPFQAEMFIQNVILVFFCVGMIAGVFPWFLVAVGPLVILFSVLHIVSRVLIRELKRLDNITQSPF LSHITSSIQGLATIHAYNKGQEFLHRYQELLDDNQAPFFLFTCAMRWLAVRLDLISIALITTTGLMIVLM HGQIPPAYAGLAISYAVQLTGLFQFTVRLASETEARFTSVERINHYIKTLSLEAPARIKNKAPSPDWPQE GEVTFENAEMRYRENLPLVLKKVSFTIKPKEKIGIVGRTGSGKSSLGMALFRLVELSGGCIKIDGVRISD IGLADLRSKLSIIPQEPVLFSGTVRSNLDPFNQYTEDQIWDALERTHMKECIAQLPLKLESEVMENGDNF SVGERQLLCIARALLRHCKILILDEATAAMDTETDLLIQETIREAFADCTMLTIAHRLHTVLGSDRIMVL AQGQVVEFDTPSVLLSNDSSRFYAMFAAAENKVAVKG TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_005688 |
| ORF Size | 4311 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_005688.4 |
| RefSeq Size | 5851 bp |
| RefSeq ORF | 4314 bp |
| Locus ID | 10057 |
| UniProt ID | O15440 |
| Domains | ABC_membrane, ABC_tran, AAA |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | ABC transporters |
| MW | 160.5 kDa |
| Gene Summary | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC224017L1 | Lenti-ORF clone of ABCC5 (Myc-DDK-tagged)-Human ATP-binding cassette, sub-family C (CFTR/MRP), member 5 (ABCC5), transcript variant 1 |
CNY 17,144.00 |
|
| RC224017L2 | Lenti-ORF clone of ABCC5 (mGFP-tagged)-Human ATP-binding cassette, sub-family C (CFTR/MRP), member 5 (ABCC5), transcript variant 1 |
CNY 7,600.00 |
|
| RC224017L3 | Lenti-ORF clone of ABCC5 (Myc-DDK-tagged)-Human ATP-binding cassette, sub-family C (CFTR/MRP), member 5 (ABCC5), transcript variant 1 |
CNY 17,144.00 |
|
| RC224017L4 | Lenti-ORF clone of ABCC5 (mGFP-tagged)-Human ATP-binding cassette, sub-family C (CFTR/MRP), member 5 (ABCC5), transcript variant 1 |
CNY 17,144.00 |
|
| RG224017 | ABCC5 (tGFP-tagged) - Human ATP-binding cassette, sub-family C (CFTR/MRP), member 5 (ABCC5), transcript variant 1 |
CNY 16,344.00 |
|
| SC308972 | ABCC5 (untagged)-Human ATP-binding cassette, sub-family C (CFTR/MRP), member 5 (ABCC5), transcript variant 1 |
CNY 14,760.00 |
