TWEAKR (TNFRSF12A) (NM_016639) Human Tagged ORF Clone
CAT#: RC201041
TNFRSF12A (Myc-DDK-tagged)-Human tumor necrosis factor receptor superfamily, member 12A (TNFRSF12A)
ORF Plasmid: tGFP
"NM_016639" in other vectors (6)
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CNY 1,200.00
CNY 3,705.00
Cited in 1 publication. |
CNY 300.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Synonyms | CD266; FN14; TWEAKR |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RC201041 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCTCGGGGCTCGCTGCGCCGGTTGCTGCGGCTCCTCGTGCTGGGGCTCTGGCTGGCGTTGCTGCGCT CCGTGGCCGGGGAGCAAGCGCCAGGCACCGCCCCCTGCTCCCGCGGCAGCTCCTGGAGCGCGGACCTGGA CAAGTGCATGGACTGCGCGTCTTGCAGGGCGCGACCGCACAGCGACTTCTGCCTGGGCTGCGCTGCAGCA CCTCCTGCCCCCTTCCGGCTGCTTTGGCCCATCCTTGGGGGCGCTCTGAGCCTGACCTTCGTGCTGGGGC TGCTTTCTGGCTTTTTGGTCTGGAGACGATGCCGCAGGAGAGAGAAGTTCACCACCCCCATAGAGGAGAC CGGCGGAGAGGGCTGCCCAGCTGTGGCGCTGATCCAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC201041 protein sequence
Red=Cloning site Green=Tags(s) MARGSLRRLLRLLVLGLWLALLRSVAGEQAPGTAPCSRGSSWSADLDKCMDCASCRARPHSDFCLGCAAA PPAPFRLLWPILGGALSLTFVLGLLSGFLVWRRCRRREKFTTPIEETGGEGCPAVALIQ TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Chromatograms |
CHROMATOGRAMS
Sequencher program is needed, download here. |
Restriction Sites | SgfI-MluI Cloning Scheme for this gene Plasmid Map |
ACCN | NM_016639 |
ORF Size | 387 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_016639.3 |
RefSeq Size | 1048 bp |
RefSeq ORF | 390 bp |
Locus ID | 51330 |
UniProt ID | Q9NP84 |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Cytokine-cytokine receptor interaction |
MW | 13.9 kDa |
Gene Summary | Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.[UniProtKB/Swiss-Prot Function] |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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Overexpression of Fn14 promotes androgen-independent prostate cancer progression through MMP-9 and correlates with poor treatment outcome
,Mingguo Huang, Shintaro Narita, Norihiko Tsuchiya, Zhiyong Ma, Kazuyuki Numakura, Takashi Obara, Hiroshi Tsuruta, Mitsuru Saito, Takamitsu Inoue, Yohei Horikawa, Shigeru Satoh, and Tomonori Habuchi,
Carcinogenesis, Sep 2011; 10.1093/carcin/bgr182.
[TWEAKR]
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC201041L1 | Lenti ORF clone of Human tumor necrosis factor receptor superfamily, member 12A (TNFRSF12A), Myc-DDK-tagged |
CNY 3,600.00 |
|
RC201041L2 | Lenti ORF clone of Human tumor necrosis factor receptor superfamily, member 12A (TNFRSF12A), mGFP tagged |
CNY 5,890.00 |
|
RC201041L3 | Lenti ORF clone of Human tumor necrosis factor receptor superfamily, member 12A (TNFRSF12A), Myc-DDK-tagged |
CNY 3,600.00 |
|
RC201041L4 | Lenti ORF clone of Human tumor necrosis factor receptor superfamily, member 12A (TNFRSF12A), mGFP tagged |
CNY 3,600.00 |
|
RG201041 | TNFRSF12A (tGFP-tagged) - Human tumor necrosis factor receptor superfamily, member 12A (TNFRSF12A) |
CNY 2,800.00 |
|
SC114174 | TNFRSF12A (untagged)-Human tumor necrosis factor receptor superfamily, member 12A (TNFRSF12A) |
CNY 1,200.00 |