CHAD Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 1-2µg/ml.IHC starting at 5µg/mL.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Chondroadherin antibody was raised against a 17 amino acid peptide near the carboxy terminus of human Chondroadherin. The immunogen is located within the last 50 amino acids of Chondroadherin.
Formulation	Chondroadherin antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Chondroadherin antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 38 kDa; Observed: 36 kDa
Gene Name	chondroadherin
Database Link	NP_001258 Entrez Gene 1101 Human UniProt ID O15335
Background	Chondroadherin, also known as CHAD or SLRR4A, belongs to the small leucine-rich proteoglycan (SLRP) family and class IV subfamily and plays a significant role in the regulation of chondrocyte growth and proliferation (1,2). It localizes to the extracellular matrix and contains nine tandem leucine repeats as well as N-terminal and C-terminal leucine rich domains (2-4). Chondroadherin is implicated in the adhesion of fibroblasts, osteoblasts and chondrocytes, which is mediated by interactions with Integrin alpha2 beta1 (2,4,5).
Synonyms	chondroadherin; SLRR4A
Note	Chondroadherin antibody can be used for detection of Chondroadherin by Western blot at 1 - 2 µg/ml. Antibody can also be used for immunocytochemistry starting at 5 µg/mL.
Reference Data

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