SH3KBP1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Jurkat cells IHC: 30-150 Positive control: Human liver cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human SH3KBP1
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	73 kDa
Gene Name	SH3 domain containing kinase binding protein 1
Database Link	NP_114098 Entrez Gene 58194 MouseEntrez Gene 84357 RatEntrez Gene 30011 Human UniProt ID Q96B97
Background	This gene encodes an adapter protein that contains three N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The encoded protein facilitates protein-protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin-dependent endocytosis. Alternate splicing results in multiple transcript variants.
Synonyms	CD2BP3; CIN85; GIG10; HSB-1; HSB1; MIG18
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Endocytosis

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