Trpv3 Mouse Monoclonal Antibody [Clone ID: S15-39]

Specifications

Product Data
Clone Name	S15-39
Applications	WB
Recommend Dilution	WB: 1-10ug/ml, IHC: 0.1-1.0ug/ml, IF: 1.0-10ug/ml
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Synthetic peptide amino acids 458-474 (cytoplasmic C-terminus) of rat TrpV3
Formulation	PBS pH7.4, 50% glycerol
Concentration	lot specific
Purification	Protein G Purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	transient receptor potential cation channel, subfamily V, member 3
Database Link	NP_001020928 Entrez Gene 162514 HumanEntrez Gene 246788 MouseEntrez Gene 497948 Rat
Background	The TRPV3 protein belongs to a family of nonselective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. The thermosensitive members of this family are expressed in subsets of sensory neurons that terminate in the skin, and are activated at distinct physiological temperatures. This channel is activated at temperatures between 22 and 40 degrees C. The gene lies in close proximity to another family member (TRPV1) gene on chromosome 17, and the two encoded proteins are thought to associate with each other to form heteromeric channels .
Synonyms	VRL-3; VRL3
Note	Detects ~70kDa.
Reference Data

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