Protein S (PROS1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 50-200 Positive control: Human thyroid cancer Predicted cell location: Cytoplasm
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 484-666 amino acids of human protein S (alpha)
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	protein S (alpha)
Database Link	NP_000304 Entrez Gene 5627 Human UniProt ID P07225
Background	This gene encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease; activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free; functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3.
Synonyms	PROS; PS21; PS22; PS23; PS24; PS25; PSA; THPH5; THPH6
Reference Data
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	Complement and coagulation cascades

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