CRF1 (CRHR1) Goat Polyclonal Antibody

Specifications

Product Data
Applications	IF, PEP-ELISA, WB
Recommend Dilution	ELISA: 1:32,000, WB: 0.1-0.3µg/ml, IF: 2ug/ml.
Reactivity	Human, Mouse, Rat
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence C-NEEKKSKVHYH, from the internal region of the protein sequence according to NP_004373.2.
Formulation	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	corticotropin releasing hormone receptor 1
Database Link	NP_001138618 Entrez Gene 12921 MouseEntrez Gene 58959 RatEntrez Gene 1394 Human UniProt ID P34998
Background	This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants.
Synonyms	CRF-R; CRF-R-1; CRF-R1; CRF1; CRFR-1; CRFR1; CRH-R-1; CRH-R1; CRHR; CRHR1L
Note	This product was successfully used on cryosection of mouse brain
Reference Data
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	Long-term depression, Neuroactive ligand-receptor interaction

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