ICAM5 Goat Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	ELISA: 1:128,000. WB: , 2-4µg/ml.
Reactivity	Human, Mouse, Rat, Pig, Cow
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence C-ESPAEGEVFAIQ, from the C Terminus of the protein sequence according to NP_003250.2.
Formulation	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	intercellular adhesion molecule 5
Database Link	NP_003250 Entrez Gene 15898 MouseEntrez Gene 313785 RatEntrez Gene 7087 Human UniProt ID Q9UMF0
Background	The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases. [provided by RefSeq]
Synonyms	TLCN; TLN
Reference Data
Protein Families	Transmembrane

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