Ptprc Mouse Monoclonal Antibody [Clone ID: OX-1]

Specifications

Product Data
Clone Name	OX-1
Applications	FC, IHC
Recommend Dilution	Flow Cytometry: Use 10 µl of 1/100 diluted antibody to label 10e6 cells in 100 µl.  Immunofluorescence. Immunohistochemistry on Frozen Sections.  The epitope recognized by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing. The use of acetone fixation for frozen sections is recommended.
Reactivity	Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Rat thymocyte membrane glycoproteins
Specificity	SM274P recognizes CD45, also known as the leucocyte common antigen (LCA). The leucocyte common antigen consists of a family of heavily glycosylated membrane glycoproteins of molecular weight 180 - 240 kDa. Antibodies recognizing a common epitope on all of these isoforms are termed CD45, whilst those recognising only individual isoforms are termed CD45RA, CD45RO etc. OX-1 reacts with all forms of CD45 expressed by all haematopoietic cells, except erythrocytes. This product is routinely tested by flow cytometry on rat splenocytes.
Formulation	0.09 % Sodium Azide State: Purified State: Liquid purifped Ig fraction from tissue culture supernatant
Concentration	lot specific
Purification	Protein G Chromatography
Conjugation	Unconjugated
Storage Condition	Store at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	protein tyrosine phosphatase, receptor type, C
Database Link	Entrez Gene 24699 Rat UniProt ID P04157
Background	CD45 isoforms play complex roles in T-cell and B-cell antigen receptor signal transduction.
Synonyms	PTPRC, Leukocyte common antigen, L-CA, T200
Reference Data

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