CYP2A13 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	Western blot: 1/500-1/1000. Immunohistochemistry on paraffin sections: 1/50-1/200. Immunofluorescence: 1/50-1/200.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide, corresponding to amino acids 306-360 of Human CYP2A13.
Specificity	This antibody detects endogenous levels of CYP2A13 protein. (region surrounding asn338)
Formulation	Phosphate buffered saline (PBS), pH 7.2. State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.05% sodium azide
Concentration	1.0 mg/ml
Purification	Affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	~ 56 kDa
Gene Name	cytochrome P450 family 2 subfamily A member 13
Database Link	Entrez Gene 1553 Human UniProt ID Q16696
Background	CYP2A13 belongs to the cytochrome P450 superfamily. These anzymes are monooxygenases which catalyze several reactions related to drug metabolism and to the synthesis of cholesterol, steroids and other lipids. CYP2A13 is involved in the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a nitrosamine specific to tobacco.
Synonyms	Cytochrome P450 2A13, CYPIIA13
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Caffeine metabolism, Drug metabolism - cytochrome P450, Drug metabolism - other enzymes, Metabolic pathways, Retinol metabolism

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