VEGF Receptor 1 (FLT1) Mouse Monoclonal Antibody [Clone ID: V12]

Specifications

Product Data
Clone Name	V12
Applications	IF, IHC, WB
Recommend Dilution	Western Blot: 1 - 2 μg/ml. Immunohistochemistry on frozen sections: 2 - 4 μg/ml. Immunocytochemistry.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human VEGF-1 receptor
Specificity	This antibody reacts to VEGFR-1.
Formulation	1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative State: Purified State: Lyphilized purified Ig fraction
Reconstitution Method	Restore with 1.2% sodium acetate or neutral PBS
Concentration	0,1 mg/ml (after reconstitution with PBS)
Purification	Affinity chromatography
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at -20°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	fms related tyrosine kinase 1
Database Link	Entrez Gene 2321 Human UniProt ID P17948
Background	VEGFR1, also known as FMS-related tyrosine kinase 1(FLT1). Oncogene FLT belongs to the src gene family and is related to oncogene ROS . Like other members of this family, it shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation. FLT is mapped to 13q12. VEGF receptor 1 signaling is essential for osteoclast development and bone marrow formation in colony-stimulating factor 1-deficient mice.
Synonyms	VEGFR1, FLT1, FLT, FRT, VEGF Receptor 1
Reference Data
Protein Families	Druggable Genome, Protein Kinase, Secreted Protein
Protein Pathways	Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion

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