Over-expression Lysates

Proteins

Over-expression Lysates

Human

IGF1

BAX

BID

CDK2

CDK6

CDKN2A

IGFBP3

P16INK4A

P53

RRM2

SIAH1

TP53

TP53I3

CASP8

CD95

CHEK1

CHK1

FAS

APAF1

BBC3

BCL2 BINDING COMPONENT 3

CASP3

CASP9

CASPASE 9

CD82

CDK1

CDK4

CHEK2

CHK2

DDB2

DR5

EI24

GADD45A

GADD45B

GTSE1

MDM2

P53 AIP1

P53R2

P73

PAI1

PERP

PIG3

PPM1D

PTEN

RRM2B

SERPINE1

SKP2

TNFRSF10B

TP53AIP1

TP73

14-3-3 SIGMA

ADGRB1

BAI1

CASPASE 3

CASPASE 8

CCNB2

CCND1

CCND2

CCND3

CCNE1

CCNE2

CCNG1

CCNG2

CDKN1A

CYCLIN B2

CYCLIN D1

CYCLIN D2

CYCLIN D3

CYCLIN E1

CYCLIN E2

CYCLIN G

CYCLIN G2

CYCS

CYTOCHROME C

LRDD

MASPIN

MDM4

MDMX

NOXA

P21

PIDD1

PIRH2

PMAIP1

RCHY1

SERPINB5

SFN

THBS1

THROMBOSPONDIN 1

TSC2

TUBERIN

HEK293T

C-Myc/DDK

Druggable Genome

Stem cell - Pluripotency

Transmembrane

Secreted Protein

Protein Kinase

Transcription Factors

ES Cell Differentiation/IPS

Protease

Phosphatase

Stem cell relevant signaling - DSL/Notch pathway

Stem cell relevant signaling - JAK/STAT signaling pathway

Stem cell relevant signaling - Wnt Signaling pathway

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Neuroactive ligand-receptor interaction

Focal adhesion

Regulation of actin cytoskeleton

Chemokine signaling pathway

Neurotrophin signaling pathway

Calcium signaling pathway

Jak-STAT signaling pathway

Wnt signaling pathway

Insulin signaling pathway

Cell cycle

T cell receptor signaling pathway

Progesterone-mediated oocyte maturation

ErbB signaling pathway

Endocytosis

Natural killer cell mediated cytotoxicity

Hematopoietic cell lineage

Toll-like receptor signaling pathway

Purine metabolism

Apoptosis

Prostate cancer

Oocyte meiosis

Axon guidance

GnRH signaling pathway

Colorectal cancer

Alzheimer's disease

Pancreatic cancer

Melanogenesis

Adherens junction

Tight junction

Ubiquitin mediated proteolysis

Leukocyte transendothelial migration

Small cell lung cancer

Vascular smooth muscle contraction

Gap junction

Chronic myeloid leukemia

TGF-beta signaling pathway

Renal cell carcinoma

Fc epsilon RI signaling pathway

Lysosome

Melanoma

Glioma

VEGF signaling pathway

Huntington's disease

Cell adhesion molecules (CAMs)

Dilated cardiomyopathy

B cell receptor signaling pathway

Acute myeloid leukemia

Hypertrophic cardiomyopathy (HCM)

Adipocytokine signaling pathway

Fc gamma R-mediated phagocytosis

Long-term potentiation

p53 signaling pathway

Complement and coagulation cascades

Non-small cell lung cancer

Endometrial cancer

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

NOD-like receptor signaling pathway

Long-term depression

Phosphatidylinositol signaling system

Olfactory transduction

RIG-I-like receptor signaling pathway

Amyotrophic lateral sclerosis (ALS)

ECM-receptor interaction

Glycolysis / Gluconeogenesis

Epithelial cell signaling in Helicobacter pylori infection

PPAR signaling pathway

Bladder cancer

Pathogenic Escherichia coli infection

Thyroid cancer

Inositol phosphate metabolism

Type II diabetes mellitus

mTOR signaling pathway

Antigen processing and presentation

Drug metabolism - cytochrome P450

Metabolism of xenobiotics by cytochrome P450

Cardiac muscle contraction

Valine

Basal cell carcinoma

Cytosolic DNA-sensing pathway

Hedgehog signaling pathway

Retinol metabolism

Glycerophospholipid metabolism

Arginine and proline metabolism

Pyrimidine metabolism

Viral myocarditis

Glycerolipid metabolism

Primary immunodeficiency

leucine and isoleucine degradation

Base excision repair

Parkinson's disease

Drug metabolism - other enzymes

Arachidonic acid metabolism

Nucleotide excision repair

Tyrosine metabolism

Prion diseases

Vibrio cholerae infection

Taste transduction

Fatty acid metabolism

Autoimmune thyroid disease

Fructose and mannose metabolism

Lysine degradation

Pyruvate metabolism

Sphingolipid metabolism

SNARE interactions in vesicular transport

Glutathione metabolism

Systemic lupus erythematosus

Tryptophan metabolism

Notch signaling pathway

Butanoate metabolism

Starch and sucrose metabolism

Amino sugar and nucleotide sugar metabolism

Galactose metabolism

Proteasome

Histidine metabolism

Pentose phosphate pathway

Regulation of autophagy

Alanine

Cysteine and methionine metabolism

Linoleic acid metabolism

Type I diabetes mellitus

aspartate and glutamate metabolism

Propanoate metabolism

Nitrogen metabolism

Homologous recombination

Androgen and estrogen metabolism

Oxidative phosphorylation

Ether lipid metabolism

Maturity onset diabetes of the young

Renin-angiotensin system

Ribosome

Dorso-ventral axis formation

Citrate cycle (TCA cycle)

Mismatch repair

Porphyrin and chlorophyll metabolism

Allograft rejection

beta-Alanine metabolism

Riboflavin metabolism

Aminoacyl-tRNA biosynthesis

DNA replication

Glycosaminoglycan degradation

Pantothenate and CoA biosynthesis

Phenylalanine metabolism

Spliceosome

ABC transporters

Other glycan degradation

Selenoamino acid metabolism

C21-Steroid hormone metabolism

Glycine

Graft-versus-host disease

leucine and isoleucine biosynthesis

serine and threonine metabolism

Circadian rhythm - mammal

Non-homologous end-joining

N-Glycan biosynthesis

Primary bile acid biosynthesis

Asthma

Folate biosynthesis

alpha-Linolenic acid metabolism

Basal transcription factors

Steroid biosynthesis

Terpenoid backbone biosynthesis

Ascorbate and aldarate metabolism

Limonene and pinene degradation

Pentose and glucuronate interconversions

Synthesis and degradation of ketone bodies

Glycosphingolipid biosynthesis - globo series

Glyoxylate and dicarboxylate metabolism

RNA degradation

Thiamine metabolism

Nicotinate and nicotinamide metabolism

One carbon pool by folate

Ubiquinone and other terpenoid-quinone biosynthesis

Sulfur metabolism

Glycosphingolipid biosynthesis - lacto and neolacto series

Biosynthesis of unsaturated fatty acids

Caffeine metabolism

Fatty acid elongation in mitochondria

Methane metabolism

Taurine and hypotaurine metabolism

RNA polymerase

Fatty acid biosynthesis

Glycosphingolipid biosynthesis - ganglio series

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Heparan sulfate biosynthesis

Phenylalanine

Protein export

tyrosine and tryptophan biosynthesis

O-Glycan biosynthesis

Vitamin B6 metabolism

Biotin metabolism

Chondroitin sulfate biosynthesis

D-Arginine and D-ornithine metabolism

D-Glutamine and D-glutamate metabolism

Keratan sulfate biosynthesis

1

Yes