Over-expression Lysates

Proteins

Over-expression Lysates

Human

DTX2

NUMB

APH1A

CTBP1

CTBP2

DVL1

RBPJ

LFNG

LUNATIC FRINGE

MANIC FRINGE

RBPJK

DLL1

DLL3

DTX3

DTX3L

DTX4

EP300

HDAC1

HDAC2

HES1

HES5

KAT2A

KAT2B

KAT3A / CBP

MAML1

MAML2

NOTCH1

NOTCH4

NUMBL

PTCRA

RFNG

DISHEVELLED 2

DVL2

JAG1

JAGGED1

MFNG

NCOA62

NCSTN

NICASTRIN

PEN2

PRESENILIN 1

PRESENILIN 2

PSEN1

PSEN2

PSENEN

RBPJL

RBPSUHL

SNW1

HEK293T

C-Myc/DDK

Druggable Genome

Transmembrane

Transcription Factors

ES Cell Differentiation/IPS

Stem cell relevant signaling - DSL/Notch pathway

Adult stem cells

Cancer stem cells

Stem cell - Pluripotency

Protease

Stem cell relevant signaling - Wnt Signaling pathway

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Regulation of actin cytoskeleton

Neuroactive ligand-receptor interaction

Focal adhesion

Endocytosis

Chemokine signaling pathway

Neurotrophin signaling pathway

Wnt signaling pathway

Calcium signaling pathway

Purine metabolism

Huntington's disease

Alzheimer's disease

Ubiquitin mediated proteolysis

Jak-STAT signaling pathway

Insulin signaling pathway

Axon guidance

Natural killer cell mediated cytotoxicity

Cell cycle

Tight junction

Oocyte meiosis

Cell adhesion molecules (CAMs)

Leukocyte transendothelial migration

Progesterone-mediated oocyte maturation

Lysosome

T cell receptor signaling pathway

Olfactory transduction

ErbB signaling pathway

Hematopoietic cell lineage

Toll-like receptor signaling pathway

Melanogenesis

Systemic lupus erythematosus

GnRH signaling pathway

Spliceosome

Prostate cancer

Apoptosis

Fc gamma R-mediated phagocytosis

Vascular smooth muscle contraction

Colorectal cancer

Adherens junction

Parkinson's disease

Oxidative phosphorylation

Dilated cardiomyopathy

Pancreatic cancer

Antigen processing and presentation

Pyrimidine metabolism

Hypertrophic cardiomyopathy (HCM)

Small cell lung cancer

VEGF signaling pathway

Melanoma

TGF-beta signaling pathway

Fc epsilon RI signaling pathway

B cell receptor signaling pathway

Chronic myeloid leukemia

Gap junction

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Glioma

Renal cell carcinoma

Acute myeloid leukemia

Adipocytokine signaling pathway

PPAR signaling pathway

p53 signaling pathway

Complement and coagulation cascades

Long-term potentiation

Ribosome

Phosphatidylinositol signaling system

Glycolysis / Gluconeogenesis

Epithelial cell signaling in Helicobacter pylori infection

Long-term depression

RIG-I-like receptor signaling pathway

NOD-like receptor signaling pathway

Cardiac muscle contraction

Non-small cell lung cancer

Pathogenic Escherichia coli infection

Endometrial cancer

Glycerophospholipid metabolism

Viral myocarditis

ECM-receptor interaction

Drug metabolism - cytochrome P450

Metabolism of xenobiotics by cytochrome P450

Vibrio cholerae infection

Amyotrophic lateral sclerosis (ALS)

Arginine and proline metabolism

Cytosolic DNA-sensing pathway

Valine

mTOR signaling pathway

Basal cell carcinoma

Hedgehog signaling pathway

Inositol phosphate metabolism

Retinol metabolism

Thyroid cancer

Drug metabolism - other enzymes

Glutathione metabolism

Bladder cancer

RNA degradation

leucine and isoleucine degradation

Amino sugar and nucleotide sugar metabolism

Arachidonic acid metabolism

Type II diabetes mellitus

Fatty acid metabolism

Proteasome

Autoimmune thyroid disease

Glycerolipid metabolism

Starch and sucrose metabolism

Pyruvate metabolism

Nucleotide excision repair

Notch signaling pathway

Tryptophan metabolism

Tyrosine metabolism

Lysine degradation

Base excision repair

Taste transduction

Type I diabetes mellitus

SNARE interactions in vesicular transport

Sphingolipid metabolism

Primary immunodeficiency

Fructose and mannose metabolism

Graft-versus-host disease

Alanine

aspartate and glutamate metabolism

Butanoate metabolism

Cysteine and methionine metabolism

N-Glycan biosynthesis

Prion diseases

Glycosphingolipid biosynthesis - lacto and neolacto series

Propanoate metabolism

Allograft rejection

Aminoacyl-tRNA biosynthesis

Androgen and estrogen metabolism

Citrate cycle (TCA cycle)

DNA replication

Ether lipid metabolism

Pentose phosphate pathway

Porphyrin and chlorophyll metabolism

Glycine

Regulation of autophagy

serine and threonine metabolism

Histidine metabolism

Nitrogen metabolism

Selenoamino acid metabolism

Galactose metabolism

O-Glycan biosynthesis

Basal transcription factors

Dorso-ventral axis formation

Linoleic acid metabolism

Nicotinate and nicotinamide metabolism

Asthma

Homologous recombination

Maturity onset diabetes of the young

RNA polymerase

beta-Alanine metabolism

Glycosaminoglycan degradation

Sulfur metabolism

Mismatch repair

Phenylalanine metabolism

Pantothenate and CoA biosynthesis

Primary bile acid biosynthesis

Biosynthesis of unsaturated fatty acids

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Heparan sulfate biosynthesis

Riboflavin metabolism

Pentose and glucuronate interconversions

Keratan sulfate biosynthesis

Other glycan degradation

Renin-angiotensin system

Terpenoid backbone biosynthesis

Ascorbate and aldarate metabolism

One carbon pool by folate

alpha-Linolenic acid metabolism

Chondroitin sulfate biosynthesis

Glycosphingolipid biosynthesis - globo series

Glyoxylate and dicarboxylate metabolism

leucine and isoleucine biosynthesis

Limonene and pinene degradation

ABC transporters

C21-Steroid hormone metabolism

Circadian rhythm - mammal

Glycosphingolipid biosynthesis - ganglio series

Non-homologous end-joining

Steroid biosynthesis

Taurine and hypotaurine metabolism

Caffeine metabolism

Folate biosynthesis

Thiamine metabolism

Cyanoamino acid metabolism

Fatty acid elongation in mitochondria

Synthesis and degradation of ketone bodies

Protein export

Ubiquinone and other terpenoid-quinone biosynthesis

Fatty acid biosynthesis

Methane metabolism

Lipoic acid metabolism

D-Glutamine and D-glutamate metabolism

Lysine biosynthesis

Phenylalanine

Vitamin B6 metabolism

tyrosine and tryptophan biosynthesis

O-Mannosyl glycan biosynthesis

Biotin metabolism

D-Arginine and D-ornithine metabolism

1

Yes