Over-expression Lysates

Proteins

Over-expression Lysates

Human

BDNF

CHRM2

NRG1

ZFYVE27

CD1E

ICAM2

MYADM

SIGLEC6

TSPAN4

B3GALT5

CLDND1

FGFR1

FXYD6

GCNT1

GGT1

KCNMB3

MGAT1

MME

IL5RA

P2RX2

ACBD4

ADAM29

BACE1

CCR2

CD33

CEACAM20

DGCR2

FOLR1

FXYD3

GDNF

GJB6

GPR85

GRAMD2B

GSG1

HSD17B13

NIPA2

NRP2

PIGT

PTPN5

RNF182

SLC14A1

SLC37A4

ST3GAL3

TMEM176B

TMEM51

ZDHHC4

ARMCX3

CD151

CLDN14

DPP8

GABA A RECEPTOR ALPHA 1

GABRA1

IL17RC

KCNH2

PMP22

STEAP3

VAMP1

ACSL5

AMELX

ARMCX6

ATG9A

BACE2

BTN2A2

BTNL8

CD36

CD44

CD84

CD8A

CHST8

CLEC2D

COLQ

CRELD1

CSF1

CUTA

CYBC1

CYHR1

CYP3A43

DDR2

EGFR

FBXW7

FUT8

FXYD2

GAA

GJB1

GPM6B

GPR17

GPRC5C

HFE

HGF

HRH1

ICAM4

IL11RA

IL1RAP

IL21 RECEPTOR

INPP4A

ITM2C

KCNK10

KCNK7

KDELR2

KREMEN1

HEK293T

C-Myc/DDK

C-MYC/DDK

Druggable Genome

Transmembrane

Transcription Factors

Secreted Protein

Protein Kinase

Protease

ES Cell Differentiation/IPS

Stem cell - Pluripotency

GPCR

Phosphatase

Ion Channels: Other

Adult stem cells

Embryonic stem cells

Nuclear Hormone Receptor

Ion Channels: Potassium

Induced pluripotent stem cells

Cancer stem cells

P450

Ion Channels: Cys-loop Receptors

Stem cell relevant signaling - TGFb/BMP signaling pathway

Stem cell relevant signaling - JAK/STAT signaling pathway

Stem cell relevant signaling - Wnt Signaling pathway

Ion Channels: Transient receptor potential

Stem cell relevant signaling - DSL/Notch pathway

Ion Channels: Glutamate Receptors

Ion Channels: ATP Receptors

Ion Channels: Sodium

Ion Channels: Calcium

Ion Channels: Cyclic nucleotide gated

Metabolic pathways

Neuroactive ligand-receptor interaction

Cytokine-cytokine receptor interaction

Cell adhesion molecules (CAMs)

Calcium signaling pathway

Hematopoietic cell lineage

Olfactory transduction

Pathways in cancer

MAPK signaling pathway

Natural killer cell mediated cytotoxicity

Jak-STAT signaling pathway

Alzheimer's disease

Regulation of actin cytoskeleton

Antigen processing and presentation

Endocytosis

Axon guidance

Huntington's disease

Leukocyte transendothelial migration

Focal adhesion

Dilated cardiomyopathy

Chemokine signaling pathway

Hypertrophic cardiomyopathy (HCM)

Lysosome

ECM-receptor interaction

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

SNARE interactions in vesicular transport

N-Glycan biosynthesis

Vascular smooth muscle contraction

Viral myocarditis

Oxidative phosphorylation

Drug metabolism - cytochrome P450

Graft-versus-host disease

Systemic lupus erythematosus

Glycosphingolipid biosynthesis - lacto and neolacto series

Melanogenesis

Tight junction

Parkinson's disease

Neurotrophin signaling pathway

Adherens junction

Glycerophospholipid metabolism

Retinol metabolism

Cardiac muscle contraction

O-Glycan biosynthesis

Adipocytokine signaling pathway

Autoimmune thyroid disease

PPAR signaling pathway

Colorectal cancer

Allograft rejection

ErbB signaling pathway

Apoptosis

Metabolism of xenobiotics by cytochrome P450

Purine metabolism

Type I diabetes mellitus

Wnt signaling pathway

Sphingolipid metabolism

Taste transduction

Asthma

Epithelial cell signaling in Helicobacter pylori infection

Basal cell carcinoma

Arachidonic acid metabolism

Heparan sulfate biosynthesis

Melanoma

Prostate cancer

Vibrio cholerae infection

Drug metabolism - other enzymes

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

TGF-beta signaling pathway

Toll-like receptor signaling pathway

GnRH signaling pathway

Keratan sulfate biosynthesis

Starch and sucrose metabolism

Pancreatic cancer

Primary immunodeficiency

Amyotrophic lateral sclerosis (ALS)

Ether lipid metabolism

Fatty acid metabolism

Gap junction

T cell receptor signaling pathway

Androgen and estrogen metabolism

Fc gamma R-mediated phagocytosis

Hedgehog signaling pathway

Chondroitin sulfate biosynthesis

Linoleic acid metabolism

Long-term depression

Porphyrin and chlorophyll metabolism

B cell receptor signaling pathway

Glutathione metabolism

Glycerolipid metabolism

Glycosphingolipid biosynthesis - globo series

p53 signaling pathway

Pyrimidine metabolism

ABC transporters

Glycosphingolipid biosynthesis - ganglio series

Notch signaling pathway

Small cell lung cancer

Ascorbate and aldarate metabolism

Fc epsilon RI signaling pathway

Renin-angiotensin system

Long-term potentiation

Renal cell carcinoma

Chronic myeloid leukemia

Nicotinate and nicotinamide metabolism

Pentose and glucuronate interconversions

Tyrosine metabolism

Biosynthesis of unsaturated fatty acids

Steroid biosynthesis

Glioma

Bladder cancer

Complement and coagulation cascades

Insulin signaling pathway

Pathogenic Escherichia coli infection

Non-small cell lung cancer

Cytosolic DNA-sensing pathway

Galactose metabolism

Riboflavin metabolism

VEGF signaling pathway

alpha-Linolenic acid metabolism

Cyanoamino acid metabolism

Endometrial cancer

Phosphatidylinositol signaling system

Progesterone-mediated oocyte maturation

RIG-I-like receptor signaling pathway

Selenoamino acid metabolism

Taurine and hypotaurine metabolism

Tryptophan metabolism

Ubiquitin mediated proteolysis

Glycosaminoglycan degradation

Primary bile acid biosynthesis

Thyroid cancer

beta-Alanine metabolism

Caffeine metabolism

Glycine

Glycolysis / Gluconeogenesis

Inositol phosphate metabolism

Nitrogen metabolism

Oocyte meiosis

Phenylalanine metabolism

Prion diseases

Type II diabetes mellitus

serine and threonine metabolism

Acute myeloid leukemia

Amino sugar and nucleotide sugar metabolism

Arginine and proline metabolism

C21-Steroid hormone metabolism

Histidine metabolism

Limonene and pinene degradation

Lysine degradation

NOD-like receptor signaling pathway

Propanoate metabolism

Sulfur metabolism

Valine

leucine and isoleucine degradation

Butanoate metabolism

Cell cycle

Dorso-ventral axis formation

Pantothenate and CoA biosynthesis

Pyruvate metabolism

Fatty acid elongation in mitochondria

O-Mannosyl glycan biosynthesis

Other glycan degradation

Protein export

Base excision repair

Citrate cycle (TCA cycle)

1

Yes