Over-expression Lysates

Proteins

Over-expression Lysates

Human

LEF1

SMAD2

CTNNB1

MAPK8

DVL1

JNK1

JNK2

MAPK9

SMAD3

BETA CATENIN

CASEIN KINASE 1 ALPHA

AXIN 1

AXIN1

DKK1

DKK2

DKK4

FRAT1

FRAT2

SFRP1

SFRP4

SFRP5

TCF7

WIF1

WNT1

WNT2

WNT3A

WNT5A

WNT6

WNT7B

WNT8A

WNT8B

AXIN 2

AXIN2

C-JUN

CKII ALPHA

CSNK1A1

CSNK2A1

DISHEVELLED 2

DVL2

JUN

PKC ALPHA

PRKCA

HEK293T

C-Myc/DDK

Druggable Genome

Transcription Factors

Protein Kinase

ES Cell Differentiation/IPS

Secreted Protein

Transmembrane

Phosphatase

Stem cell relevant signaling - Wnt Signaling pathway

Cancer stem cells

Adult stem cells

Stem cell - Pluripotency

Stem cell relevant signaling - JAK/STAT signaling pathway

Embryonic stem cells

GPCR

Stem cell relevant signaling - TGFb/BMP signaling pathway

Induced pluripotent stem cells

Nuclear Hormone Receptor

Protease

Stem cell relevant signaling - DSL/Notch pathway

Pathways in cancer

Focal adhesion

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Wnt signaling pathway

Colorectal cancer

Hematopoietic cell lineage

Cell adhesion molecules (CAMs)

Neurotrophin signaling pathway

Regulation of actin cytoskeleton

Prostate cancer

Melanoma

ErbB signaling pathway

Jak-STAT signaling pathway

Pancreatic cancer

TGF-beta signaling pathway

Basal cell carcinoma

Adherens junction

Endometrial cancer

Melanogenesis

Natural killer cell mediated cytotoxicity

Acute myeloid leukemia

Fc gamma R-mediated phagocytosis

T cell receptor signaling pathway

Insulin signaling pathway

Progesterone-mediated oocyte maturation

Toll-like receptor signaling pathway

Fc epsilon RI signaling pathway

Hedgehog signaling pathway

Small cell lung cancer

Glioma

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Endocytosis

GnRH signaling pathway

Adipocytokine signaling pathway

B cell receptor signaling pathway

Chronic myeloid leukemia

Leukocyte transendothelial migration

ECM-receptor interaction

Huntington's disease

Maturity onset diabetes of the young

Tight junction

Apoptosis

Non-small cell lung cancer

Renal cell carcinoma

Epithelial cell signaling in Helicobacter pylori infection

Hypertrophic cardiomyopathy (HCM)

Type II diabetes mellitus

Chemokine signaling pathway

VEGF signaling pathway

mTOR signaling pathway

Dilated cardiomyopathy

Gap junction

Metabolic pathways

Pathogenic Escherichia coli infection

Systemic lupus erythematosus

Thyroid cancer

NOD-like receptor signaling pathway

Alzheimer's disease

Complement and coagulation cascades

Notch signaling pathway

Axon guidance

RIG-I-like receptor signaling pathway

Bladder cancer

Dorso-ventral axis formation

Long-term depression

Oocyte meiosis

p53 signaling pathway

Antigen processing and presentation

Autoimmune thyroid disease

Calcium signaling pathway

Primary immunodeficiency

Amyotrophic lateral sclerosis (ALS)

Prion diseases

Viral myocarditis

Allograft rejection

Cell cycle

Type I diabetes mellitus

Long-term potentiation

Vascular smooth muscle contraction

Glycolysis / Gluconeogenesis

Graft-versus-host disease

PPAR signaling pathway

Starch and sucrose metabolism

Citrate cycle (TCA cycle)

Lysosome

Neuroactive ligand-receptor interaction

Nicotinate and nicotinamide metabolism

Phosphatidylinositol signaling system

Pyruvate metabolism

Renin-angiotensin system

Retinol metabolism

Tyrosine metabolism

Vibrio cholerae infection

Parkinson's disease

Amino sugar and nucleotide sugar metabolism

Asthma

Cardiac muscle contraction

Cysteine and methionine metabolism

Drug metabolism - cytochrome P450

Drug metabolism - other enzymes

Fructose and mannose metabolism

Galactose metabolism

Inositol phosphate metabolism

Linoleic acid metabolism

Metabolism of xenobiotics by cytochrome P450

Oxidative phosphorylation

Phenylalanine

Phenylalanine metabolism

Primary bile acid biosynthesis

Purine metabolism

Pyrimidine metabolism

Regulation of autophagy

Ubiquinone and other terpenoid-quinone biosynthesis

Ubiquitin mediated proteolysis

tyrosine and tryptophan biosynthesis

1

Yes