cDNA Clones

cDNA Clones

Expression Plasmids

Mutant ORF Clones

Human

P53

BETA CATENIN

TCF7L2

CAMK2B

PRKACB

NFAT2

CAMK2D

CAMK2G

JNK1

NFAT1

PPP2R5C

JNK2

NFAT5

PKC GAMMA

CYCLIN D3

TCF7

PORCN

PPAR DELTA

PPP2R1B

PPP3CB

NFATC4

TAK1

CTBP2

LEF1

PRICKLE

SMAD3

TBL1

BETA TRCP2

CASEIN KINASE 1 ALPHA

CKII ALPHA

JNK3

PPP2R5D

SMAD2

AXIN 1

FRA1

FRIZZLED 6

GSK3 BETA

PHOSPHOLIPASE C BETA 4

PPP2R5E

VANGL1

CALCINEURIN A

NFAT4

TBL1Y

WNT2B

CAMK2A

SIAH1

BETA TRCP

CK1 EPSILON

PKC BETA 1

RAC1

MPS1

PHOSPHOLIPASE C BETA 2

SKP1

WNT16

WNT5B

WNT8A

PPP3CC

CTBP1

CTNNBIP1

DVL1

PP2A-BETA

PRESENILIN 1

PRKACA

APC

CASEIN KINASE 2 BETA

DAAM1

LRP5

NKD2

NLK

PHOSPHOLIPASE C BETA 1

PHOSPHOLIPASE C BETA 3

PPP2R5A

SIAH INTERACTING PROTEIN

WNT5A

AXIN 2

C-MYC

FZD3

PPP2R1A

CALCIUM BINDING PROTEIN P22

CSNK2A2

CULLIN 1

DAAM2

FRIZZLED 7

FRIZZLED 9

LRP6

MMP7

PKC ALPHA

PRKACG

PRKX

RAC2

ROCK2

SFRP2

TBLR1

WNT3

C-JUN

CHD8

CSNK1A1L

CYCLIN D1

CYCLIN D2

DISHEVELLED 2

Plasmids

Myc-DDK

mGFP

Tag Free

TurboGFP

pCMV6-Entry

pCMV6-AC-GFP

pLenti-C-Myc-DDK-P2A-Puro

pLenti-C-mGFP-P2A-Puro

pLenti-C-Myc-DDK

pLenti-C-mGFP

pCMV6-XL5

pCMV6-AC-Myc-DDK

pCMV6-XL4

pCMV6-AN-Myc-DDK

pCMV6-AC

pCMV6-XL6

PCMV6-Neo

No

Yes

LentiORF

TrueORF

TrueClone

TrueORF Gold, TrueORF

Druggable Genome

Transcription Factors

Protein Kinase

ES Cell Differentiation/IPS

Transmembrane

Stem cell - Pluripotency

Secreted Protein

Phosphatase

Stem cell relevant signaling - Wnt Signaling pathway

Cancer stem cells

Adult stem cells

GPCR

Stem cell relevant signaling - JAK/STAT signaling pathway

Embryonic stem cells

Stem cell relevant signaling - TGFb/BMP signaling pathway

Induced pluripotent stem cells

Nuclear Hormone Receptor

Protease

Stem cell relevant signaling - DSL/Notch pathway

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Neuroactive ligand-receptor interaction

Regulation of actin cytoskeleton

Focal adhesion

Endocytosis

Chemokine signaling pathway

Calcium signaling pathway

Insulin signaling pathway

Neurotrophin signaling pathway

Ubiquitin mediated proteolysis

Wnt signaling pathway

Olfactory transduction

Colorectal cancer

Huntington's disease

Purine metabolism

Natural killer cell mediated cytotoxicity

Alzheimer's disease

Jak-STAT signaling pathway

Prostate cancer

Progesterone-mediated oocyte maturation

Tight junction

Axon guidance

Cell cycle

Pancreatic cancer

Leukocyte transendothelial migration

T cell receptor signaling pathway

ErbB signaling pathway

Melanoma

Cell adhesion molecules (CAMs)

Oocyte meiosis

Endometrial cancer

Apoptosis

Vascular smooth muscle contraction

B cell receptor signaling pathway

GnRH signaling pathway

Melanogenesis

p53 signaling pathway

Adherens junction

Chronic myeloid leukemia

Toll-like receptor signaling pathway

Lysosome

Fc epsilon RI signaling pathway

Fc gamma R-mediated phagocytosis

Glioma

Small cell lung cancer

Dilated cardiomyopathy

Gap junction

VEGF signaling pathway

Renal cell carcinoma

Non-small cell lung cancer

Hematopoietic cell lineage

mTOR signaling pathway

Hypertrophic cardiomyopathy (HCM)

Spliceosome

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Parkinson's disease

Long-term potentiation

Acute myeloid leukemia

Long-term depression

Oxidative phosphorylation

Type II diabetes mellitus

Systemic lupus erythematosus

Pyrimidine metabolism

Bladder cancer

Thyroid cancer

Adipocytokine signaling pathway

Glycolysis / Gluconeogenesis

TGF-beta signaling pathway

Viral myocarditis

PPAR signaling pathway

Phosphatidylinositol signaling system

Amyotrophic lateral sclerosis (ALS)

Antigen processing and presentation

NOD-like receptor signaling pathway

RIG-I-like receptor signaling pathway

ECM-receptor interaction

Epithelial cell signaling in Helicobacter pylori infection

Basal cell carcinoma

Cardiac muscle contraction

Complement and coagulation cascades

Mismatch repair

Ribosome

Glycerophospholipid metabolism

Amino sugar and nucleotide sugar metabolism

Starch and sucrose metabolism

Primary immunodeficiency

Pathogenic Escherichia coli infection

Vibrio cholerae infection

Drug metabolism - cytochrome P450

Metabolism of xenobiotics by cytochrome P450

Inositol phosphate metabolism

Cytosolic DNA-sensing pathway

Hedgehog signaling pathway

Arginine and proline metabolism

Notch signaling pathway

RNA degradation

Retinol metabolism

Homologous recombination

Drug metabolism - other enzymes

Glutathione metabolism

Valine

Arachidonic acid metabolism

Galactose metabolism

Maturity onset diabetes of the young

Taste transduction

Nucleotide excision repair

Tyrosine metabolism

N-Glycan biosynthesis

Dorso-ventral axis formation

Autoimmune thyroid disease

Pyruvate metabolism

Lysine degradation

Fatty acid metabolism

leucine and isoleucine degradation

Glycerolipid metabolism

Sphingolipid metabolism

Proteasome

ABC transporters

Type I diabetes mellitus

Prion diseases

Citrate cycle (TCA cycle)

Base excision repair

Cysteine and methionine metabolism

Tryptophan metabolism

Graft-versus-host disease

Fructose and mannose metabolism

SNARE interactions in vesicular transport

Androgen and estrogen metabolism

Porphyrin and chlorophyll metabolism

Alanine

aspartate and glutamate metabolism

Allograft rejection

Ether lipid metabolism

Propanoate metabolism

DNA replication

Aminoacyl-tRNA biosynthesis

Glycosphingolipid biosynthesis - lacto and neolacto series

Glycine

serine and threonine metabolism

Regulation of autophagy

Butanoate metabolism

Histidine metabolism

Pentose phosphate pathway

Basal transcription factors

Nitrogen metabolism

Selenoamino acid metabolism

Glycosaminoglycan degradation

RNA polymerase

Phenylalanine metabolism

Linoleic acid metabolism

O-Glycan biosynthesis

Asthma

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Nicotinate and nicotinamide metabolism

Pentose and glucuronate interconversions

beta-Alanine metabolism

Biosynthesis of unsaturated fatty acids

One carbon pool by folate

Heparan sulfate biosynthesis

Keratan sulfate biosynthesis

Ascorbate and aldarate metabolism

Pantothenate and CoA biosynthesis

Steroid biosynthesis

Primary bile acid biosynthesis

Riboflavin metabolism

Other glycan degradation

Renin-angiotensin system

Chondroitin sulfate biosynthesis

alpha-Linolenic acid metabolism

Non-homologous end-joining

Sulfur metabolism

Terpenoid backbone biosynthesis

Glycosphingolipid biosynthesis - globo series

Glycosphingolipid biosynthesis - ganglio series

Glyoxylate and dicarboxylate metabolism

Circadian rhythm - mammal

Limonene and pinene degradation

Cyanoamino acid metabolism

Taurine and hypotaurine metabolism

leucine and isoleucine biosynthesis

Protein export

Folate biosynthesis

C21-Steroid hormone metabolism

Thiamine metabolism

Caffeine metabolism

Synthesis and degradation of ketone bodies

Fatty acid elongation in mitochondria

Methane metabolism

Ubiquinone and other terpenoid-quinone biosynthesis

Fatty acid biosynthesis

Lipoic acid metabolism

Lysine biosynthesis

O-Mannosyl glycan biosynthesis

Phenylalanine

tyrosine and tryptophan biosynthesis

Vitamin B6 metabolism

D-Glutamine and D-glutamate metabolism

Biotin metabolism

D-Arginine and D-ornithine metabolism

Neomycin

None

Puromycin

1

Yes

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