cDNA Clones

cDNA Clones

Expression Plasmids

Mutant ORF Clones

Human

NRG1

PI 3 KINASE CATALYTIC SUBUNIT ALPHA

EGFR

ABL2

CAMK2B

CAMK2D

CAMK2G

JNK1

KRAS

PAK3

BRAF

CBL

JNK2

PAK4

P21 RAS

RAF1

PIK3R5

NRG2

HER2

NRAS

SHC

AKT1

P21

PI 3 KINASE P85 ALPHA

PRKCG

S6K1

JNK3

PI 3 KINASE P55 GAMMA

AKT3

FAK

HRAS

EGF

ERK1

GSK3 BETA

B RAF

CAMK2A

ERBB 3

ERBB 4

PAK5

STAT5A

ELK1

NCK BETA

NRG3

PKC BETA 1

SRC

A RAF

AKT2

C ABL

ERK2

GAB1

GRB2

NCK

PAK6

PHOSPHOLIPASE C GAMMA 1

CBLB

P38

BAD

CBL C

MAP2K2

PAK1

TGF ALPHA

MEK1

MEK4

MEK7

PI 3 KINASE CATALYTIC SUBUNIT GAMMA

PIK3CB

MEK2

P27 KIP 1

P70 S6 KINASE BETA

PKC ALPHA

PKC GAMMA

PLCG 2

AMPHIREGULIN

BETACELLULIN

C-JUN

C-MYC

CRKL

EIF4EBP1

EREG

HB EGF

MAP2K1

NRG4

PI 3 KINASE P85 BETA

PIK3CD

SHC3

SHC4

SOS1

STAT5B

PAK2

SOS2

MTOR

SLI

CDKN1B

ERBB2

GSK3B

MAP2K7

MYC

NCK2

PIK3CG

SHC2

Plasmids

Myc-DDK

mGFP

Tag Free

TurboGFP

DDK-His

pCMV6-Entry

pCMV6-AC-GFP

pLenti-C-Myc-DDK-P2A-Puro

pLenti-C-mGFP-P2A-Puro

pLenti-C-Myc-DDK

pLenti-C-mGFP

pCMV6-XL5

pCMV6-XL4

pCMV6-XL6

pCMV6-AC

pCMV6-XL5-DDK-His

No

Yes

TrueORF

LentiORF

TrueClone

TrueORF Gold, TrueORF

Druggable Genome

Protein Kinase

Transmembrane

ES Cell Differentiation/IPS

Secreted Protein

Transcription Factors

Stem cell relevant signaling - JAK/STAT signaling pathway

Adult stem cells

Stem cell - Pluripotency

Cancer stem cells

Embryonic stem cells

Induced pluripotent stem cells

Stem cell relevant signaling - DSL/Notch pathway

Stem cell relevant signaling - TGFb/BMP signaling pathway

Stem cell relevant signaling - Wnt Signaling pathway

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Neuroactive ligand-receptor interaction

Regulation of actin cytoskeleton

Focal adhesion

Endocytosis

Chemokine signaling pathway

Calcium signaling pathway

Insulin signaling pathway

Neurotrophin signaling pathway

Ubiquitin mediated proteolysis

Wnt signaling pathway

Olfactory transduction

Colorectal cancer

Huntington's disease

Purine metabolism

Natural killer cell mediated cytotoxicity

Alzheimer's disease

Jak-STAT signaling pathway

Prostate cancer

Progesterone-mediated oocyte maturation

Tight junction

Axon guidance

Cell cycle

Pancreatic cancer

Leukocyte transendothelial migration

T cell receptor signaling pathway

ErbB signaling pathway

Melanoma

Cell adhesion molecules (CAMs)

Oocyte meiosis

Endometrial cancer

Apoptosis

Vascular smooth muscle contraction

B cell receptor signaling pathway

GnRH signaling pathway

Melanogenesis

p53 signaling pathway

Adherens junction

Chronic myeloid leukemia

Toll-like receptor signaling pathway

Lysosome

Fc epsilon RI signaling pathway

Fc gamma R-mediated phagocytosis

Glioma

Small cell lung cancer

Dilated cardiomyopathy

Gap junction

VEGF signaling pathway

Renal cell carcinoma

Non-small cell lung cancer

Hematopoietic cell lineage

mTOR signaling pathway

Hypertrophic cardiomyopathy (HCM)

Spliceosome

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Parkinson's disease

Long-term potentiation

Acute myeloid leukemia

Long-term depression

Oxidative phosphorylation

Type II diabetes mellitus

Systemic lupus erythematosus

Pyrimidine metabolism

Bladder cancer

Thyroid cancer

Adipocytokine signaling pathway

Glycolysis / Gluconeogenesis

TGF-beta signaling pathway

Viral myocarditis

PPAR signaling pathway

Phosphatidylinositol signaling system

Amyotrophic lateral sclerosis (ALS)

Antigen processing and presentation

NOD-like receptor signaling pathway

RIG-I-like receptor signaling pathway

ECM-receptor interaction

Epithelial cell signaling in Helicobacter pylori infection

Basal cell carcinoma

Cardiac muscle contraction

Complement and coagulation cascades

Mismatch repair

Ribosome

Glycerophospholipid metabolism

Amino sugar and nucleotide sugar metabolism

Starch and sucrose metabolism

Primary immunodeficiency

Pathogenic Escherichia coli infection

Vibrio cholerae infection

Drug metabolism - cytochrome P450

Metabolism of xenobiotics by cytochrome P450

Inositol phosphate metabolism

Cytosolic DNA-sensing pathway

Hedgehog signaling pathway

Arginine and proline metabolism

Notch signaling pathway

RNA degradation

Retinol metabolism

Homologous recombination

Drug metabolism - other enzymes

Glutathione metabolism

Valine

Arachidonic acid metabolism

Galactose metabolism

Maturity onset diabetes of the young

Taste transduction

Nucleotide excision repair

Tyrosine metabolism

N-Glycan biosynthesis

Dorso-ventral axis formation

Autoimmune thyroid disease

Pyruvate metabolism

Lysine degradation

Fatty acid metabolism

leucine and isoleucine degradation

Glycerolipid metabolism

Sphingolipid metabolism

Proteasome

ABC transporters

Prion diseases

Type I diabetes mellitus

Citrate cycle (TCA cycle)

Base excision repair

Cysteine and methionine metabolism

Tryptophan metabolism

Graft-versus-host disease

Fructose and mannose metabolism

SNARE interactions in vesicular transport

Androgen and estrogen metabolism

Porphyrin and chlorophyll metabolism

Alanine

aspartate and glutamate metabolism

Allograft rejection

Ether lipid metabolism

Propanoate metabolism

DNA replication

Aminoacyl-tRNA biosynthesis

Glycosphingolipid biosynthesis - lacto and neolacto series

Glycine

serine and threonine metabolism

Regulation of autophagy

Butanoate metabolism

Histidine metabolism

Pentose phosphate pathway

Basal transcription factors

Nitrogen metabolism

Selenoamino acid metabolism

Glycosaminoglycan degradation

RNA polymerase

Phenylalanine metabolism

Linoleic acid metabolism

O-Glycan biosynthesis

Asthma

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Nicotinate and nicotinamide metabolism

Pentose and glucuronate interconversions

beta-Alanine metabolism

Biosynthesis of unsaturated fatty acids

One carbon pool by folate

Heparan sulfate biosynthesis

Keratan sulfate biosynthesis

Ascorbate and aldarate metabolism

Pantothenate and CoA biosynthesis

Steroid biosynthesis

Primary bile acid biosynthesis

Riboflavin metabolism

Other glycan degradation

Renin-angiotensin system

Chondroitin sulfate biosynthesis

alpha-Linolenic acid metabolism

Non-homologous end-joining

Sulfur metabolism

Terpenoid backbone biosynthesis

Glycosphingolipid biosynthesis - globo series

Glycosphingolipid biosynthesis - ganglio series

Glyoxylate and dicarboxylate metabolism

Circadian rhythm - mammal

Limonene and pinene degradation

Cyanoamino acid metabolism

Taurine and hypotaurine metabolism

leucine and isoleucine biosynthesis

Protein export

Folate biosynthesis

C21-Steroid hormone metabolism

Thiamine metabolism

Caffeine metabolism

Synthesis and degradation of ketone bodies

Fatty acid elongation in mitochondria

Methane metabolism

Ubiquinone and other terpenoid-quinone biosynthesis

Fatty acid biosynthesis

Lipoic acid metabolism

Lysine biosynthesis

O-Mannosyl glycan biosynthesis

Phenylalanine

tyrosine and tryptophan biosynthesis

Vitamin B6 metabolism

D-Glutamine and D-glutamate metabolism

Biotin metabolism

D-Arginine and D-ornithine metabolism

Neomycin

None

Puromycin

1

Yes

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