cDNA Clones

cDNA Clones

Expression Plasmids

Human

HNF 4 ALPHA

GLUCOKINASE

NR5A2

PAX6

PYRUVATE KINASE

AMYLIN

HES1

HEX

HNF1 ALPHA

HNF1 BETA

INSULIN

MAFA

NEUROD1

SLC2A2

Plasmids

mGFP

pCMV6-Entry

pCMV6-AC-GFP

pLenti-C-Myc-DDK-P2A-Puro

pLenti-C-mGFP-P2A-Puro

pLenti-C-Myc-DDK

pLenti-C-mGFP

pCMV6-XL5

pCMV6-XL4

pCMV6-AC

No

LentiORF

Druggable Genome

Transcription Factors

ES Cell Differentiation/IPS

Embryonic stem cells

Nuclear Hormone Receptor

Adult stem cells

Induced pluripotent stem cells

Secreted Protein

Cancer stem cells

Stem cell relevant signaling - DSL/Notch pathway

Transmembrane

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Neuroactive ligand-receptor interaction

Chemokine signaling pathway

Focal adhesion

Regulation of actin cytoskeleton

Neurotrophin signaling pathway

Calcium signaling pathway

Jak-STAT signaling pathway

Wnt signaling pathway

Natural killer cell mediated cytotoxicity

T cell receptor signaling pathway

Insulin signaling pathway

Toll-like receptor signaling pathway

ErbB signaling pathway

Progesterone-mediated oocyte maturation

Endocytosis

Apoptosis

Colorectal cancer

Prostate cancer

Axon guidance

Pancreatic cancer

Oocyte meiosis

Cell cycle

GnRH signaling pathway

Leukocyte transendothelial migration

Chronic myeloid leukemia

B cell receptor signaling pathway

Melanogenesis

VEGF signaling pathway

Alzheimer's disease

Gap junction

Fc epsilon RI signaling pathway

Small cell lung cancer

Cell adhesion molecules (CAMs)

Melanoma

Renal cell carcinoma

Vascular smooth muscle contraction

Adherens junction

TGF-beta signaling pathway

Ubiquitin mediated proteolysis

Hematopoietic cell lineage

Glioma

NOD-like receptor signaling pathway

Adipocytokine signaling pathway

Tight junction

Acute myeloid leukemia

Fc gamma R-mediated phagocytosis

Non-small cell lung cancer

Long-term potentiation

Purine metabolism

RIG-I-like receptor signaling pathway

Huntington's disease

p53 signaling pathway

Dilated cardiomyopathy

Endometrial cancer

Amyotrophic lateral sclerosis (ALS)

Long-term depression

Hypertrophic cardiomyopathy (HCM)

Bladder cancer

Lysosome

Epithelial cell signaling in Helicobacter pylori infection

Type II diabetes mellitus

Complement and coagulation cascades

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

mTOR signaling pathway

Hedgehog signaling pathway

ECM-receptor interaction

Phosphatidylinositol signaling system

Basal cell carcinoma

Glycolysis / Gluconeogenesis

Pathogenic Escherichia coli infection

Cytosolic DNA-sensing pathway

PPAR signaling pathway

Thyroid cancer

Parkinson's disease

Viral myocarditis

Antigen processing and presentation

Primary immunodeficiency

Arginine and proline metabolism

Metabolism of xenobiotics by cytochrome P450

Retinol metabolism

Olfactory transduction

Autoimmune thyroid disease

Nucleotide excision repair

ABC transporters

Drug metabolism - cytochrome P450

Lysine degradation

Valine

Cardiac muscle contraction

Vibrio cholerae infection

Arachidonic acid metabolism

Inositol phosphate metabolism

Prion diseases

Regulation of autophagy

Tyrosine metabolism

leucine and isoleucine degradation

Drug metabolism - other enzymes

Base excision repair

Maturity onset diabetes of the young

Notch signaling pathway

Pyruvate metabolism

Systemic lupus erythematosus

Taste transduction

Fructose and mannose metabolism

Pyrimidine metabolism

Starch and sucrose metabolism

Tryptophan metabolism

Type I diabetes mellitus

Galactose metabolism

Glycerophospholipid metabolism

Sphingolipid metabolism

Amino sugar and nucleotide sugar metabolism

Cysteine and methionine metabolism

Androgen and estrogen metabolism

Glutathione metabolism

Allograft rejection

Citrate cycle (TCA cycle)

Fatty acid metabolism

Glycerolipid metabolism

Homologous recombination

Dorso-ventral axis formation

Linoleic acid metabolism

Renin-angiotensin system

Propanoate metabolism

Spliceosome

Mismatch repair

Nitrogen metabolism

Oxidative phosphorylation

Alanine

Ether lipid metabolism

Graft-versus-host disease

Histidine metabolism

Pentose phosphate pathway

Phenylalanine metabolism

Proteasome

SNARE interactions in vesicular transport

aspartate and glutamate metabolism

Butanoate metabolism

Circadian rhythm - mammal

Glycosaminoglycan degradation

Glycine

Non-homologous end-joining

Porphyrin and chlorophyll metabolism

serine and threonine metabolism

DNA replication

Ribosome

C21-Steroid hormone metabolism

Other glycan degradation

Riboflavin metabolism

beta-Alanine metabolism

Asthma

Primary bile acid biosynthesis

Steroid biosynthesis

Aminoacyl-tRNA biosynthesis

Folate biosynthesis

N-Glycan biosynthesis

Basal transcription factors

Glycosphingolipid biosynthesis - globo series

Terpenoid backbone biosynthesis

alpha-Linolenic acid metabolism

Ascorbate and aldarate metabolism

Glyoxylate and dicarboxylate metabolism

Nicotinate and nicotinamide metabolism

Pantothenate and CoA biosynthesis

Pentose and glucuronate interconversions

leucine and isoleucine biosynthesis

Glycosphingolipid biosynthesis - lacto and neolacto series

Limonene and pinene degradation

One carbon pool by folate

RNA degradation

Selenoamino acid metabolism

Biosynthesis of unsaturated fatty acids

Glycosphingolipid biosynthesis - ganglio series

Methane metabolism

Thiamine metabolism

Caffeine metabolism

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Protein export

Taurine and hypotaurine metabolism

Fatty acid elongation in mitochondria

Heparan sulfate biosynthesis

O-Glycan biosynthesis

Synthesis and degradation of ketone bodies

Ubiquinone and other terpenoid-quinone biosynthesis

Vitamin B6 metabolism

D-Arginine and D-ornithine metabolism

D-Glutamine and D-glutamate metabolism

Keratan sulfate biosynthesis

Phenylalanine

Sulfur metabolism

tyrosine and tryptophan biosynthesis

None

1

Yes

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