Expression Plasmids

cDNA Clones

Expression Plasmids

Human

P53

EVI1

ACTIVIN A RECEPTOR TYPE IC

IKK GAMMA

MDM2

P16INK4A

SHC

SMAD3

ACTIVIN A RECEPTOR TYPE IB

AKT1

CTBP2

ERK1

P21 RAS

PI 3 KINASE P85 ALPHA

RUNX1

AKT3

BAD

BCL X

BCR

C ABL

CBL C

CDK6

CTBP1

ERK2

GAB2

GRB2

IKK BETA

KRAS

NF-KB P65

NFKB1

P21

P38

PI 3 KINASE P55 GAMMA

PIK3R5

TGF BETA 2

TGF BETA RECEPTOR I

TGF BETA RECEPTOR II

A RAF

AKT2

B RAF

C-MYC

CBL

CBLB

CDK4

CRKL

CYCLIN D1

E2F1

E2F2

E2F3

HDAC1

HDAC2

IKB ALPHA

IKK ALPHA

MEK1

MEK2

NRAS

P27 KIP 1

PI 3 KINASE CATALYTIC SUBUNIT ALPHA

PI 3 KINASE CATALYTIC SUBUNIT GAMMA

PI 3 KINASE P85 BETA

PIK3CB

PIK3CD

RAF1

RB

SHC3

SHC4

SHP2

SLI

SMAD4

SOS1

SOS2

STAT5A

STAT5B

TGF BETA 1

TGF BETA 3

Plasmids

Myc-DDK

pCMV6-Entry

pCMV6-AC-GFP

pLenti-C-Myc-DDK-P2A-Puro

pLenti-C-mGFP-P2A-Puro

pLenti-C-Myc-DDK

pLenti-C-mGFP

pCMV6-XL5

pCMV6-XL4

pCMV6-XL6

pCMV6-AC

No

LentiORF

Druggable Genome

Transcription Factors

Protein Kinase

ES Cell Differentiation/IPS

Transmembrane

Stem cell - Pluripotency

Stem cell relevant signaling - JAK/STAT signaling pathway

Embryonic stem cells

Stem cell relevant signaling - TGFb/BMP signaling pathway

Stem cell relevant signaling - Wnt Signaling pathway

Cancer stem cells

Secreted Protein

Stem cell relevant signaling - DSL/Notch pathway

Adult stem cells

Induced pluripotent stem cells

Phosphatase

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Neuroactive ligand-receptor interaction

Cytokine-cytokine receptor interaction

Olfactory transduction

Regulation of actin cytoskeleton

Endocytosis

Focal adhesion

Chemokine signaling pathway

Calcium signaling pathway

Purine metabolism

Wnt signaling pathway

Huntington's disease

Neurotrophin signaling pathway

Alzheimer's disease

Ubiquitin mediated proteolysis

Jak-STAT signaling pathway

Axon guidance

Natural killer cell mediated cytotoxicity

Insulin signaling pathway

Cell adhesion molecules (CAMs)

Progesterone-mediated oocyte maturation

Tight junction

Cell cycle

Leukocyte transendothelial migration

Lysosome

Oocyte meiosis

T cell receptor signaling pathway

ErbB signaling pathway

Adherens junction

Fc gamma R-mediated phagocytosis

Prostate cancer

Toll-like receptor signaling pathway

Apoptosis

Hematopoietic cell lineage

Melanogenesis

Spliceosome

Vascular smooth muscle contraction

Oxidative phosphorylation

GnRH signaling pathway

Parkinson's disease

Dilated cardiomyopathy

Systemic lupus erythematosus

Colorectal cancer

Hypertrophic cardiomyopathy (HCM)

Pancreatic cancer

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

VEGF signaling pathway

Pyrimidine metabolism

Melanoma

B cell receptor signaling pathway

Gap junction

TGF-beta signaling pathway

PPAR signaling pathway

p53 signaling pathway

Chronic myeloid leukemia

Small cell lung cancer

Renal cell carcinoma

Antigen processing and presentation

Fc epsilon RI signaling pathway

Viral myocarditis

Acute myeloid leukemia

Complement and coagulation cascades

Glioma

RIG-I-like receptor signaling pathway

Adipocytokine signaling pathway

NOD-like receptor signaling pathway

Long-term potentiation

Phosphatidylinositol signaling system

Ribosome

Long-term depression

Epithelial cell signaling in Helicobacter pylori infection

Glycerophospholipid metabolism

Cardiac muscle contraction

Glycolysis / Gluconeogenesis

Endometrial cancer

Amyotrophic lateral sclerosis (ALS)

Drug metabolism - cytochrome P450

ECM-receptor interaction

Metabolism of xenobiotics by cytochrome P450

Pathogenic Escherichia coli infection

Non-small cell lung cancer

Vibrio cholerae infection

Basal cell carcinoma

mTOR signaling pathway

Bladder cancer

Cytosolic DNA-sensing pathway

Inositol phosphate metabolism

Drug metabolism - other enzymes

Retinol metabolism

Arginine and proline metabolism

Valine

Hedgehog signaling pathway

Arachidonic acid metabolism

Starch and sucrose metabolism

Glutathione metabolism

RNA degradation

Thyroid cancer

N-Glycan biosynthesis

Sphingolipid metabolism

Type II diabetes mellitus

Glycerolipid metabolism

Amino sugar and nucleotide sugar metabolism

Tyrosine metabolism

Fatty acid metabolism

leucine and isoleucine degradation

Autoimmune thyroid disease

Pyruvate metabolism

Lysine degradation

Cysteine and methionine metabolism

Primary immunodeficiency

Proteasome

Taste transduction

ABC transporters

Base excision repair

Nucleotide excision repair

Tryptophan metabolism

Type I diabetes mellitus

Notch signaling pathway

SNARE interactions in vesicular transport

Ether lipid metabolism

Alanine

aspartate and glutamate metabolism

Androgen and estrogen metabolism

Porphyrin and chlorophyll metabolism

Fructose and mannose metabolism

Graft-versus-host disease

Prion diseases

Aminoacyl-tRNA biosynthesis

Butanoate metabolism

Glycine

serine and threonine metabolism

Citrate cycle (TCA cycle)

Allograft rejection

Glycosphingolipid biosynthesis - lacto and neolacto series

Propanoate metabolism

Basal transcription factors

DNA replication

Galactose metabolism

Pentose phosphate pathway

Selenoamino acid metabolism

Nitrogen metabolism

Histidine metabolism

Glycosaminoglycan degradation

Homologous recombination

O-Glycan biosynthesis

Regulation of autophagy

Linoleic acid metabolism

Maturity onset diabetes of the young

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Nicotinate and nicotinamide metabolism

Dorso-ventral axis formation

Mismatch repair

Phenylalanine metabolism

RNA polymerase

Asthma

Pentose and glucuronate interconversions

Heparan sulfate biosynthesis

Primary bile acid biosynthesis

beta-Alanine metabolism

Biosynthesis of unsaturated fatty acids

Keratan sulfate biosynthesis

Ascorbate and aldarate metabolism

Pantothenate and CoA biosynthesis

One carbon pool by folate

Renin-angiotensin system

Riboflavin metabolism

Chondroitin sulfate biosynthesis

Other glycan degradation

Sulfur metabolism

alpha-Linolenic acid metabolism

Steroid biosynthesis

Glycosphingolipid biosynthesis - globo series

Terpenoid backbone biosynthesis

Non-homologous end-joining

leucine and isoleucine biosynthesis

Glyoxylate and dicarboxylate metabolism

Glycosphingolipid biosynthesis - ganglio series

Cyanoamino acid metabolism

Limonene and pinene degradation

Taurine and hypotaurine metabolism

C21-Steroid hormone metabolism

Circadian rhythm - mammal

Folate biosynthesis

Caffeine metabolism

Synthesis and degradation of ketone bodies

Protein export

Thiamine metabolism

Fatty acid elongation in mitochondria

Methane metabolism

Ubiquinone and other terpenoid-quinone biosynthesis

Lipoic acid metabolism

O-Mannosyl glycan biosynthesis

Fatty acid biosynthesis

Phenylalanine

Vitamin B6 metabolism

tyrosine and tryptophan biosynthesis

Lysine biosynthesis

D-Glutamine and D-glutamate metabolism

Biotin metabolism

D-Arginine and D-ornithine metabolism

Puromycin

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