Expression Plasmids

cDNA Clones

Expression Plasmids

Human

HNF 4 ALPHA

GLUCOKINASE

FOXA2

NR5A2

PAX6

PYRUVATE KINASE

AMYLIN

FOXA3

HES1

HEX

HNF1 ALPHA

HNF1 BETA

HNF6

INSULIN

MAFA

NEUROD1

NEUROGENIN3

NKX2.2

NKX6.1

PAX4

PDX1

SLC2A2

Plasmids

Myc-DDK

pCMV6-Entry

pCMV6-AC-GFP

pLenti-C-Myc-DDK-P2A-Puro

pLenti-C-mGFP-P2A-Puro

pLenti-C-Myc-DDK

pLenti-C-mGFP

pCMV6-XL5

pCMV6-XL4

pCMV6-AC

No

LentiORF

Druggable Genome

Transcription Factors

ES Cell Differentiation/IPS

Embryonic stem cells

Nuclear Hormone Receptor

Adult stem cells

Induced pluripotent stem cells

Secreted Protein

Cancer stem cells

Stem cell relevant signaling - DSL/Notch pathway

Transmembrane

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Neuroactive ligand-receptor interaction

Regulation of actin cytoskeleton

Focal adhesion

Chemokine signaling pathway

Neurotrophin signaling pathway

Wnt signaling pathway

Endocytosis

Calcium signaling pathway

Jak-STAT signaling pathway

Natural killer cell mediated cytotoxicity

Insulin signaling pathway

Leukocyte transendothelial migration

T cell receptor signaling pathway

Toll-like receptor signaling pathway

Cell adhesion molecules (CAMs)

Ubiquitin mediated proteolysis

Alzheimer's disease

Axon guidance

ErbB signaling pathway

Progesterone-mediated oocyte maturation

Huntington's disease

Prostate cancer

Melanogenesis

Tight junction

Cell cycle

Oocyte meiosis

Colorectal cancer

GnRH signaling pathway

Apoptosis

Pancreatic cancer

Vascular smooth muscle contraction

B cell receptor signaling pathway

Fc gamma R-mediated phagocytosis

Chronic myeloid leukemia

Purine metabolism

Adherens junction

VEGF signaling pathway

Fc epsilon RI signaling pathway

Hematopoietic cell lineage

Melanoma

Small cell lung cancer

TGF-beta signaling pathway

Gap junction

Renal cell carcinoma

Lysosome

RIG-I-like receptor signaling pathway

Glioma

Adipocytokine signaling pathway

Dilated cardiomyopathy

Acute myeloid leukemia

Parkinson's disease

Long-term potentiation

NOD-like receptor signaling pathway

p53 signaling pathway

Hypertrophic cardiomyopathy (HCM)

Non-small cell lung cancer

Spliceosome

Antigen processing and presentation

Endometrial cancer

Long-term depression

Epithelial cell signaling in Helicobacter pylori infection

Amyotrophic lateral sclerosis (ALS)

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Systemic lupus erythematosus

Type II diabetes mellitus

mTOR signaling pathway

Hedgehog signaling pathway

ECM-receptor interaction

Basal cell carcinoma

PPAR signaling pathway

Complement and coagulation cascades

Viral myocarditis

Bladder cancer

Oxidative phosphorylation

Cytosolic DNA-sensing pathway

Glycolysis / Gluconeogenesis

Pathogenic Escherichia coli infection

Arginine and proline metabolism

Phosphatidylinositol signaling system

Vibrio cholerae infection

Cardiac muscle contraction

Pyrimidine metabolism

Ribosome

Glycerophospholipid metabolism

Autoimmune thyroid disease

Metabolism of xenobiotics by cytochrome P450

Retinol metabolism

Thyroid cancer

Olfactory transduction

Notch signaling pathway

Drug metabolism - cytochrome P450

Lysine degradation

Primary immunodeficiency

Type I diabetes mellitus

Valine

Arachidonic acid metabolism

Nucleotide excision repair

Prion diseases

Tryptophan metabolism

ABC transporters

Pyruvate metabolism

Regulation of autophagy

Sphingolipid metabolism

Starch and sucrose metabolism

Tyrosine metabolism

leucine and isoleucine degradation

Amino sugar and nucleotide sugar metabolism

Drug metabolism - other enzymes

Inositol phosphate metabolism

Maturity onset diabetes of the young

Glutathione metabolism

Graft-versus-host disease

N-Glycan biosynthesis

Proteasome

RNA degradation

Taste transduction

Allograft rejection

Citrate cycle (TCA cycle)

Cysteine and methionine metabolism

Fructose and mannose metabolism

Glycerolipid metabolism

Androgen and estrogen metabolism

Fatty acid metabolism

Dorso-ventral axis formation

Ether lipid metabolism

Base excision repair

Propanoate metabolism

Alanine

aspartate and glutamate metabolism

Galactose metabolism

SNARE interactions in vesicular transport

Glycine

Nitrogen metabolism

serine and threonine metabolism

Butanoate metabolism

DNA replication

Linoleic acid metabolism

Asthma

Glycosaminoglycan degradation

Glycosphingolipid biosynthesis - lacto and neolacto series

Histidine metabolism

Homologous recombination

Porphyrin and chlorophyll metabolism

O-Glycan biosynthesis

Pentose phosphate pathway

Phenylalanine metabolism

Biosynthesis of unsaturated fatty acids

Renin-angiotensin system

beta-Alanine metabolism

Aminoacyl-tRNA biosynthesis

Circadian rhythm - mammal

Mismatch repair

Heparan sulfate biosynthesis

Nicotinate and nicotinamide metabolism

Non-homologous end-joining

Ascorbate and aldarate metabolism

One carbon pool by folate

Pentose and glucuronate interconversions

Primary bile acid biosynthesis

alpha-Linolenic acid metabolism

Basal transcription factors

Glycosphingolipid biosynthesis - ganglio series

Glycosphingolipid biosynthesis - globo series

Other glycan degradation

Riboflavin metabolism

Selenoamino acid metabolism

Steroid biosynthesis

C21-Steroid hormone metabolism

Limonene and pinene degradation

RNA polymerase

Terpenoid backbone biosynthesis

Glyoxylate and dicarboxylate metabolism

Keratan sulfate biosynthesis

Folate biosynthesis

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Protein export

Methane metabolism

Pantothenate and CoA biosynthesis

Sulfur metabolism

Chondroitin sulfate biosynthesis

Fatty acid elongation in mitochondria

Taurine and hypotaurine metabolism

Thiamine metabolism

leucine and isoleucine biosynthesis

Cyanoamino acid metabolism

Caffeine metabolism

Fatty acid biosynthesis

Synthesis and degradation of ketone bodies

Vitamin B6 metabolism

D-Glutamine and D-glutamate metabolism

Ubiquinone and other terpenoid-quinone biosynthesis

Phenylalanine

tyrosine and tryptophan biosynthesis

Biotin metabolism

D-Arginine and D-ornithine metabolism

Lipoic acid metabolism

Lysine biosynthesis

O-Mannosyl glycan biosynthesis

None

1

Yes

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