Expression Plasmids

cDNA Clones

Expression Plasmids

Human

TCF7L2

P53

MLH1

EGFR

TCF7

INTEGRIN LINKED KINASE

PIK3R5

CTNNA2

HER2

LEF1

P21 RAS

PI 3 KINASE P85 ALPHA

AKT1

PI 3 KINASE P55 GAMMA

BETA CATENIN

AKT3

CTNNA3

PDPK1

CASPASE 9

EGF

ERK1

GSK3 BETA

ALPHA 1 CATENIN

ELK1

FOXO3

A RAF

AKT2

AXIN 1

ERK2

GRB2

KRAS

BAD

APC

PI 3 KINASE CATALYTIC SUBUNIT GAMMA

PIK3CB

RAF1

MEK1

MEK2

B RAF

C-MYC

CYCLIN D1

E CADHERIN

NRAS

PI 3 KINASE CATALYTIC SUBUNIT ALPHA

PI 3 KINASE P85 BETA

PIK3CD

PTEN

SOS1

AXIN 2

SOS2

TCF7L1

TP53

CTNNA1

ERBB2

GSK3B

PIK3CG

ARAF

MAPK1

Plasmids

Myc-DDK

Tag Free

mGFP

TurboGFP

DDK-His

pCMV6-Entry

pCMV6-AC-GFP

pLenti-C-Myc-DDK-P2A-Puro

pLenti-C-mGFP-P2A-Puro

pLenti-C-Myc-DDK

pLenti-C-mGFP

pCMV6-XL5

pCMV6-XL4

pCMV6-AC

pCMV6-XL5-DDK-His

pCMV6-XL6

No

Yes

LentiORF

TrueORF

TrueClone

TrueORF Gold, TrueORF

Druggable Genome

Protein Kinase

Transcription Factors

ES Cell Differentiation/IPS

Stem cell - Pluripotency

Transmembrane

Adult stem cells

Stem cell relevant signaling - JAK/STAT signaling pathway

Induced pluripotent stem cells

Cancer stem cells

Secreted Protein

Stem cell relevant signaling - Wnt Signaling pathway

Embryonic stem cells

Protease

Phosphatase

Stem cell relevant signaling - DSL/Notch pathway

Stem cell relevant signaling - TGFb/BMP signaling pathway

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Neuroactive ligand-receptor interaction

Cytokine-cytokine receptor interaction

Regulation of actin cytoskeleton

Focal adhesion

Endocytosis

Calcium signaling pathway

Chemokine signaling pathway

Olfactory transduction

Wnt signaling pathway

Neurotrophin signaling pathway

Huntington's disease

Purine metabolism

Alzheimer's disease

Ubiquitin mediated proteolysis

Jak-STAT signaling pathway

Axon guidance

Insulin signaling pathway

Progesterone-mediated oocyte maturation

Natural killer cell mediated cytotoxicity

Tight junction

Leukocyte transendothelial migration

Cell cycle

Cell adhesion molecules (CAMs)

Oocyte meiosis

T cell receptor signaling pathway

Lysosome

Vascular smooth muscle contraction

ErbB signaling pathway

Prostate cancer

Apoptosis

Adherens junction

GnRH signaling pathway

Toll-like receptor signaling pathway

Melanogenesis

Fc gamma R-mediated phagocytosis

Dilated cardiomyopathy

Colorectal cancer

Hematopoietic cell lineage

Hypertrophic cardiomyopathy (HCM)

Spliceosome

Parkinson's disease

Pancreatic cancer

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

VEGF signaling pathway

Small cell lung cancer

Gap junction

Oxidative phosphorylation

Systemic lupus erythematosus

Melanoma

p53 signaling pathway

Pyrimidine metabolism

B cell receptor signaling pathway

Chronic myeloid leukemia

Renal cell carcinoma

Long-term potentiation

TGF-beta signaling pathway

Viral myocarditis

PPAR signaling pathway

Fc epsilon RI signaling pathway

Acute myeloid leukemia

Adipocytokine signaling pathway

Glioma

Antigen processing and presentation

Long-term depression

NOD-like receptor signaling pathway

RIG-I-like receptor signaling pathway

ECM-receptor interaction

Endometrial cancer

Phosphatidylinositol signaling system

Cardiac muscle contraction

Epithelial cell signaling in Helicobacter pylori infection

Complement and coagulation cascades

Ribosome

Amyotrophic lateral sclerosis (ALS)

Non-small cell lung cancer

Glycerophospholipid metabolism

mTOR signaling pathway

Type II diabetes mellitus

Glycolysis / Gluconeogenesis

Drug metabolism - cytochrome P450

Metabolism of xenobiotics by cytochrome P450

Bladder cancer

Pathogenic Escherichia coli infection

Basal cell carcinoma

Vibrio cholerae infection

Cytosolic DNA-sensing pathway

Hedgehog signaling pathway

Arginine and proline metabolism

Inositol phosphate metabolism

RNA degradation

Retinol metabolism

Drug metabolism - other enzymes

Valine

Arachidonic acid metabolism

Glutathione metabolism

Thyroid cancer

Amino sugar and nucleotide sugar metabolism

Starch and sucrose metabolism

Tyrosine metabolism

N-Glycan biosynthesis

Autoimmune thyroid disease

Taste transduction

Pyruvate metabolism

Lysine degradation

Fatty acid metabolism

Glycerolipid metabolism

leucine and isoleucine degradation

Sphingolipid metabolism

Nucleotide excision repair

Notch signaling pathway

Proteasome

Primary immunodeficiency

ABC transporters

Type I diabetes mellitus

Base excision repair

Cysteine and methionine metabolism

Tryptophan metabolism

Prion diseases

Graft-versus-host disease

Fructose and mannose metabolism

SNARE interactions in vesicular transport

Citrate cycle (TCA cycle)

Androgen and estrogen metabolism

Porphyrin and chlorophyll metabolism

Alanine

aspartate and glutamate metabolism

Allograft rejection

Ether lipid metabolism

Propanoate metabolism

DNA replication

Aminoacyl-tRNA biosynthesis

Glycosphingolipid biosynthesis - lacto and neolacto series

Glycine

serine and threonine metabolism

Regulation of autophagy

Butanoate metabolism

Homologous recombination

Histidine metabolism

Pentose phosphate pathway

Galactose metabolism

Basal transcription factors

Maturity onset diabetes of the young

Nitrogen metabolism

Selenoamino acid metabolism

Mismatch repair

Dorso-ventral axis formation

Glycosaminoglycan degradation

RNA polymerase

Phenylalanine metabolism

Linoleic acid metabolism

O-Glycan biosynthesis

Asthma

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Nicotinate and nicotinamide metabolism

Pentose and glucuronate interconversions

beta-Alanine metabolism

Biosynthesis of unsaturated fatty acids

One carbon pool by folate

Heparan sulfate biosynthesis

Keratan sulfate biosynthesis

Ascorbate and aldarate metabolism

Pantothenate and CoA biosynthesis

Steroid biosynthesis

Primary bile acid biosynthesis

Riboflavin metabolism

Other glycan degradation

Renin-angiotensin system

Chondroitin sulfate biosynthesis

alpha-Linolenic acid metabolism

Non-homologous end-joining

Sulfur metabolism

Terpenoid backbone biosynthesis

Glycosphingolipid biosynthesis - globo series

Glycosphingolipid biosynthesis - ganglio series

Glyoxylate and dicarboxylate metabolism

Circadian rhythm - mammal

Limonene and pinene degradation

Cyanoamino acid metabolism

Taurine and hypotaurine metabolism

leucine and isoleucine biosynthesis

Protein export

Folate biosynthesis

C21-Steroid hormone metabolism

Thiamine metabolism

Caffeine metabolism

Synthesis and degradation of ketone bodies

Fatty acid elongation in mitochondria

Methane metabolism

Ubiquinone and other terpenoid-quinone biosynthesis

Fatty acid biosynthesis

Lipoic acid metabolism

Lysine biosynthesis

O-Mannosyl glycan biosynthesis

Phenylalanine

tyrosine and tryptophan biosynthesis

Vitamin B6 metabolism

D-Glutamine and D-glutamate metabolism

Biotin metabolism

D-Arginine and D-ornithine metabolism

Neomycin

None

Puromycin

1

Yes

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