Expression Plasmids

cDNA Clones

Expression Plasmids

Human

FRIZZLED 6

WNT16

BMP2

FRIZZLED 10

FRIZZLED 2

FRIZZLED 4

FRIZZLED 5

FRIZZLED 7

FRIZZLED 8

FRIZZLED 9

FRIZZLED HOMOLOG 1

FZD3

PTCH1

SMOOTHENED

SONIC HEDGEHOG

WNT1

WNT10A

WNT11

WNT3

WNT6

WNT7A

WNT7B

WNT9A

WNT9B

Plasmids

mGFP

pCMV6-Entry

pCMV6-AC-GFP

pLenti-C-Myc-DDK-P2A-Puro

pLenti-C-mGFP-P2A-Puro

pLenti-C-Myc-DDK

pLenti-C-mGFP

pCMV6-XL5

pCMV6-XL4

pCMV6-AC

pCMV6-XL6

No

LentiORF

Druggable Genome

Secreted Protein

Transmembrane

ES Cell Differentiation/IPS

Cancer stem cells

Adult stem cells

Transcription Factors

Stem cell relevant signaling - Wnt Signaling pathway

GPCR

Embryonic stem cells

Induced pluripotent stem cells

Stem cell relevant signaling - TGFb/BMP signaling pathway

Protein Kinase

Stem cell - Pluripotency

Stem cell relevant signaling - DSL/Notch pathway

Neuroactive ligand-receptor interaction

Metabolic pathways

Cytokine-cytokine receptor interaction

Cell adhesion molecules (CAMs)

Pathways in cancer

Calcium signaling pathway

Hematopoietic cell lineage

MAPK signaling pathway

Natural killer cell mediated cytotoxicity

Regulation of actin cytoskeleton

Jak-STAT signaling pathway

Endocytosis

Leukocyte transendothelial migration

Alzheimer's disease

Chemokine signaling pathway

Dilated cardiomyopathy

Focal adhesion

Axon guidance

Melanogenesis

ECM-receptor interaction

Colorectal cancer

Antigen processing and presentation

Huntington's disease

Lysosome

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Hypertrophic cardiomyopathy (HCM)

Adherens junction

Wnt signaling pathway

ABC transporters

N-Glycan biosynthesis

Vascular smooth muscle contraction

Parkinson's disease

Apoptosis

Basal cell carcinoma

Gap junction

Systemic lupus erythematosus

Viral myocarditis

Neurotrophin signaling pathway

Toll-like receptor signaling pathway

Retinol metabolism

Tight junction

Amyotrophic lateral sclerosis (ALS)

Autoimmune thyroid disease

Graft-versus-host disease

TGF-beta signaling pathway

Adipocytokine signaling pathway

Allograft rejection

ErbB signaling pathway

Oxidative phosphorylation

PPAR signaling pathway

Prostate cancer

Cardiac muscle contraction

Drug metabolism - cytochrome P450

Melanoma

Type I diabetes mellitus

Vibrio cholerae infection

Androgen and estrogen metabolism

Glycerophospholipid metabolism

Glycosphingolipid biosynthesis - lacto and neolacto series

Pancreatic cancer

Primary immunodeficiency

Purine metabolism

Sphingolipid metabolism

T cell receptor signaling pathway

Metabolism of xenobiotics by cytochrome P450

O-Glycan biosynthesis

Olfactory transduction

Asthma

B cell receptor signaling pathway

Epithelial cell signaling in Helicobacter pylori infection

Hedgehog signaling pathway

SNARE interactions in vesicular transport

Starch and sucrose metabolism

Complement and coagulation cascades

Drug metabolism - other enzymes

Long-term potentiation

GnRH signaling pathway

Heparan sulfate biosynthesis

Notch signaling pathway

Small cell lung cancer

Taste transduction

p53 signaling pathway

Chronic myeloid leukemia

Long-term depression

Renin-angiotensin system

Fatty acid metabolism

Fc gamma R-mediated phagocytosis

Glycerolipid metabolism

Prion diseases

Arachidonic acid metabolism

Ascorbate and aldarate metabolism

Ether lipid metabolism

Glycosphingolipid biosynthesis - ganglio series

Keratan sulfate biosynthesis

Porphyrin and chlorophyll metabolism

Biosynthesis of unsaturated fatty acids

Bladder cancer

Glycosphingolipid biosynthesis - globo series

Linoleic acid metabolism

Pentose and glucuronate interconversions

Progesterone-mediated oocyte maturation

Fc epsilon RI signaling pathway

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Insulin signaling pathway

Pathogenic Escherichia coli infection

RIG-I-like receptor signaling pathway

Renal cell carcinoma

Steroid biosynthesis

Tyrosine metabolism

Glioma

Oocyte meiosis

Primary bile acid biosynthesis

Ubiquitin mediated proteolysis

Cytosolic DNA-sensing pathway

Endometrial cancer

Galactose metabolism

Non-small cell lung cancer

Riboflavin metabolism

Thyroid cancer

Type II diabetes mellitus

Chondroitin sulfate biosynthesis

Glycosaminoglycan degradation

Nicotinate and nicotinamide metabolism

Tryptophan metabolism

Amino sugar and nucleotide sugar metabolism

C21-Steroid hormone metabolism

Glycolysis / Gluconeogenesis

NOD-like receptor signaling pathway

Nitrogen metabolism

Pyrimidine metabolism

Acute myeloid leukemia

Arginine and proline metabolism

Caffeine metabolism

Cell cycle

Glutathione metabolism

Histidine metabolism

Limonene and pinene degradation

Phenylalanine metabolism

Propanoate metabolism

VEGF signaling pathway

Valine

alpha-Linolenic acid metabolism

beta-Alanine metabolism

leucine and isoleucine degradation

Butanoate metabolism

Dorso-ventral axis formation

Glycine

Inositol phosphate metabolism

Lysine degradation

Other glycan degradation

Pantothenate and CoA biosynthesis

Phosphatidylinositol signaling system

Protein export

Pyruvate metabolism

Terpenoid backbone biosynthesis

serine and threonine metabolism

Base excision repair

Citrate cycle (TCA cycle)

Cyanoamino acid metabolism

Fatty acid elongation in mitochondria

Maturity onset diabetes of the young

O-Mannosyl glycan biosynthesis

Selenoamino acid metabolism

Sulfur metabolism

Taurine and hypotaurine metabolism

Ubiquinone and other terpenoid-quinone biosynthesis

None

1

Yes

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