Expression Plasmids

cDNA Clones

Expression Plasmids

Human

ARSA

GBA

NEU4

SPHK1

ASAH1

ASAH2

GLB1

PPAP2C

SMPD4

SPHINGOMYELIN SYNTHASE 2

ACID SPHINGOMYELINASE

DEGS1

GALACTOSYLCERAMIDASE

PHOSPHATIDIC ACID PHOSPHATASE TYPE 2B

PPAP2A

SPTLC1

UGT8

ASAH3

ASAH3L

BETA 1,4 GALACTOSYLTRANSFERASE 6

CERAMIDE GLUCOSYLTRANSFERASE

CERK

DEGS2

ENPP7

FVT1

GAL3ST1

GALACTOSIDASE ALPHA

NEU2

NEURAMINIDASE

NSMASE

NSMASE2

PHYTOCERAMIDASE

SERINE PALMITOYLTRANSFERASE

SGPL1

SIALIDASE 3

SPHINGOMYELIN SYNTHASE 1

SPHINGOSINE 1 PHOSPHATE PHOSPHATASE 1

SPHINGOSINE 1 PHOSPHATE PHOSPHATASE 2

SPHK2

Plasmids

Myc-DDK

mGFP

pLenti-C-Myc-DDK-P2A-Puro

pLenti-C-mGFP-P2A-Puro

No

LentiORF

Druggable Genome

Transmembrane

Stem cell - Pluripotency

Phosphatase

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Neuroactive ligand-receptor interaction

Cytokine-cytokine receptor interaction

Olfactory transduction

Regulation of actin cytoskeleton

Endocytosis

Focal adhesion

Chemokine signaling pathway

Calcium signaling pathway

Purine metabolism

Wnt signaling pathway

Huntington's disease

Neurotrophin signaling pathway

Alzheimer's disease

Ubiquitin mediated proteolysis

Jak-STAT signaling pathway

Axon guidance

Natural killer cell mediated cytotoxicity

Insulin signaling pathway

Progesterone-mediated oocyte maturation

Tight junction

Cell adhesion molecules (CAMs)

Cell cycle

Leukocyte transendothelial migration

Oocyte meiosis

Lysosome

T cell receptor signaling pathway

ErbB signaling pathway

Adherens junction

Fc gamma R-mediated phagocytosis

Prostate cancer

Toll-like receptor signaling pathway

Apoptosis

Hematopoietic cell lineage

Melanogenesis

Spliceosome

Vascular smooth muscle contraction

Oxidative phosphorylation

GnRH signaling pathway

Parkinson's disease

Dilated cardiomyopathy

Systemic lupus erythematosus

Colorectal cancer

Hypertrophic cardiomyopathy (HCM)

Pancreatic cancer

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

VEGF signaling pathway

Pyrimidine metabolism

Melanoma

B cell receptor signaling pathway

TGF-beta signaling pathway

Gap junction

PPAR signaling pathway

p53 signaling pathway

Chronic myeloid leukemia

Small cell lung cancer

Renal cell carcinoma

Antigen processing and presentation

Fc epsilon RI signaling pathway

Viral myocarditis

Acute myeloid leukemia

Complement and coagulation cascades

Glioma

RIG-I-like receptor signaling pathway

Adipocytokine signaling pathway

NOD-like receptor signaling pathway

Long-term potentiation

Phosphatidylinositol signaling system

Ribosome

Long-term depression

Glycerophospholipid metabolism

Epithelial cell signaling in Helicobacter pylori infection

Cardiac muscle contraction

Glycolysis / Gluconeogenesis

Endometrial cancer

Amyotrophic lateral sclerosis (ALS)

Drug metabolism - cytochrome P450

ECM-receptor interaction

Metabolism of xenobiotics by cytochrome P450

Pathogenic Escherichia coli infection

Non-small cell lung cancer

Vibrio cholerae infection

Basal cell carcinoma

mTOR signaling pathway

Bladder cancer

Cytosolic DNA-sensing pathway

Inositol phosphate metabolism

Drug metabolism - other enzymes

Retinol metabolism

Arginine and proline metabolism

Valine

Hedgehog signaling pathway

Arachidonic acid metabolism

Starch and sucrose metabolism

Glutathione metabolism

RNA degradation

Thyroid cancer

N-Glycan biosynthesis

Sphingolipid metabolism

Type II diabetes mellitus

Glycerolipid metabolism

Amino sugar and nucleotide sugar metabolism

Tyrosine metabolism

Fatty acid metabolism

leucine and isoleucine degradation

Autoimmune thyroid disease

Pyruvate metabolism

Lysine degradation

Cysteine and methionine metabolism

Primary immunodeficiency

Taste transduction

Proteasome

ABC transporters

Base excision repair

Nucleotide excision repair

Type I diabetes mellitus

Tryptophan metabolism

Notch signaling pathway

SNARE interactions in vesicular transport

Ether lipid metabolism

Alanine

aspartate and glutamate metabolism

Androgen and estrogen metabolism

Porphyrin and chlorophyll metabolism

Fructose and mannose metabolism

Graft-versus-host disease

Prion diseases

Aminoacyl-tRNA biosynthesis

Butanoate metabolism

Glycine

serine and threonine metabolism

Citrate cycle (TCA cycle)

Allograft rejection

Glycosphingolipid biosynthesis - lacto and neolacto series

Propanoate metabolism

Basal transcription factors

DNA replication

Galactose metabolism

Pentose phosphate pathway

Selenoamino acid metabolism

Nitrogen metabolism

Histidine metabolism

Glycosaminoglycan degradation

Homologous recombination

O-Glycan biosynthesis

Regulation of autophagy

Linoleic acid metabolism

Maturity onset diabetes of the young

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Nicotinate and nicotinamide metabolism

Dorso-ventral axis formation

Mismatch repair

Phenylalanine metabolism

RNA polymerase

Asthma

Pentose and glucuronate interconversions

Heparan sulfate biosynthesis

Primary bile acid biosynthesis

beta-Alanine metabolism

Biosynthesis of unsaturated fatty acids

Keratan sulfate biosynthesis

Ascorbate and aldarate metabolism

Pantothenate and CoA biosynthesis

One carbon pool by folate

Renin-angiotensin system

Riboflavin metabolism

Chondroitin sulfate biosynthesis

Other glycan degradation

Sulfur metabolism

alpha-Linolenic acid metabolism

Steroid biosynthesis

Glycosphingolipid biosynthesis - globo series

Terpenoid backbone biosynthesis

Non-homologous end-joining

leucine and isoleucine biosynthesis

Glyoxylate and dicarboxylate metabolism

Glycosphingolipid biosynthesis - ganglio series

Cyanoamino acid metabolism

Taurine and hypotaurine metabolism

Limonene and pinene degradation

C21-Steroid hormone metabolism

Circadian rhythm - mammal

Folate biosynthesis

Caffeine metabolism

Synthesis and degradation of ketone bodies

Protein export

Thiamine metabolism

Fatty acid elongation in mitochondria

Methane metabolism

Ubiquinone and other terpenoid-quinone biosynthesis

Lipoic acid metabolism

O-Mannosyl glycan biosynthesis

Fatty acid biosynthesis

Phenylalanine

Vitamin B6 metabolism

tyrosine and tryptophan biosynthesis

Lysine biosynthesis

D-Glutamine and D-glutamate metabolism

Biotin metabolism

D-Arginine and D-ornithine metabolism

Neomycin

Puromycin

None

1

Yes

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