Expression Plasmids

cDNA Clones

Expression Plasmids

Human

JNK1

BAX

JNK2

SMAD2

TCF7L2

ACTIVIN A RECEPTOR TYPE IC

AKT1

AKT3

AXIN 1

BCL2

BETA CATENIN

BIRC5

CASPASE 9

EGFR

ERK2

FRIZZLED 6

GRB2

GSK3 BETA

JNK3

KRAS

P53

PI 3 KINASE P55 GAMMA

PI 3 KINASE P85 ALPHA

PIK3R5

RAC1

TGF BETA 2

TGF BETA RECEPTOR I

TGF BETA RECEPTOR II

A RAF

ACTIVIN A RECEPTOR TYPE IB

AKT2

APC

APPL

B RAF

BAD

C FOS

C-JUN

C-MYC

CASPASE 3

CYCLIN D1

CYTOCHROME C

DCC

DISHEVELLED 2

DISHEVELLED 3

DVL1

ERK1

FRIZZLED 10

FRIZZLED 2

FRIZZLED 4

FRIZZLED 5

FRIZZLED 7

FRIZZLED 8

FRIZZLED 9

FRIZZLED HOMOLOG 1

FZD3

IGF1 RECEPTOR

LEF1

MEK1

MET

MLH1

MSH2

MSH3

MSH6

PDGF RECEPTOR ALPHA

PDGF RECEPTOR BETA

PI 3 KINASE CATALYTIC SUBUNIT ALPHA

PI 3 KINASE CATALYTIC SUBUNIT GAMMA

PI 3 KINASE P85 BETA

PIK3CB

PIK3CD

RAC2

RAC3

RAF1

SMAD3

SMAD4

SOS1

TCF7

TGF BETA 1

TGF BETA 3

Plasmids

Myc-DDK

mGFP

pLenti-C-Myc-DDK

pLenti-C-mGFP

No

LentiORF

Druggable Genome

ES Cell Differentiation/IPS

Protein Kinase

Transmembrane

Transcription Factors

Stem cell - Pluripotency

GPCR

Stem cell relevant signaling - JAK/STAT signaling pathway

Cancer stem cells

Secreted Protein

Embryonic stem cells

Stem cell relevant signaling - TGFb/BMP signaling pathway

Stem cell relevant signaling - Wnt Signaling pathway

Adult stem cells

Protease

Induced pluripotent stem cells

Stem cell relevant signaling - DSL/Notch pathway

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Neuroactive ligand-receptor interaction

Regulation of actin cytoskeleton

Focal adhesion

Chemokine signaling pathway

Neurotrophin signaling pathway

Wnt signaling pathway

Endocytosis

Calcium signaling pathway

Jak-STAT signaling pathway

Natural killer cell mediated cytotoxicity

Insulin signaling pathway

Leukocyte transendothelial migration

T cell receptor signaling pathway

Toll-like receptor signaling pathway

Ubiquitin mediated proteolysis

Cell adhesion molecules (CAMs)

Alzheimer's disease

Axon guidance

ErbB signaling pathway

Progesterone-mediated oocyte maturation

Prostate cancer

Huntington's disease

Melanogenesis

Tight junction

Cell cycle

Oocyte meiosis

Apoptosis

Colorectal cancer

GnRH signaling pathway

Pancreatic cancer

Vascular smooth muscle contraction

B cell receptor signaling pathway

Fc gamma R-mediated phagocytosis

Chronic myeloid leukemia

Purine metabolism

VEGF signaling pathway

Adherens junction

Fc epsilon RI signaling pathway

Melanoma

Hematopoietic cell lineage

Small cell lung cancer

TGF-beta signaling pathway

Gap junction

Renal cell carcinoma

Lysosome

RIG-I-like receptor signaling pathway

Glioma

Adipocytokine signaling pathway

Parkinson's disease

Acute myeloid leukemia

NOD-like receptor signaling pathway

Dilated cardiomyopathy

Long-term potentiation

p53 signaling pathway

Non-small cell lung cancer

Hypertrophic cardiomyopathy (HCM)

Antigen processing and presentation

Spliceosome

Endometrial cancer

Long-term depression

Amyotrophic lateral sclerosis (ALS)

Epithelial cell signaling in Helicobacter pylori infection

Systemic lupus erythematosus

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

mTOR signaling pathway

Hedgehog signaling pathway

Type II diabetes mellitus

PPAR signaling pathway

Basal cell carcinoma

Bladder cancer

Viral myocarditis

Complement and coagulation cascades

ECM-receptor interaction

Oxidative phosphorylation

Cytosolic DNA-sensing pathway

Pathogenic Escherichia coli infection

Glycolysis / Gluconeogenesis

Arginine and proline metabolism

Phosphatidylinositol signaling system

Vibrio cholerae infection

Ribosome

Cardiac muscle contraction

Glycerophospholipid metabolism

Pyrimidine metabolism

Autoimmune thyroid disease

Metabolism of xenobiotics by cytochrome P450

Retinol metabolism

Thyroid cancer

Olfactory transduction

Drug metabolism - cytochrome P450

Notch signaling pathway

Primary immunodeficiency

Lysine degradation

Type I diabetes mellitus

Valine

Arachidonic acid metabolism

Nucleotide excision repair

Prion diseases

Tryptophan metabolism

Regulation of autophagy

Sphingolipid metabolism

Tyrosine metabolism

Starch and sucrose metabolism

leucine and isoleucine degradation

Pyruvate metabolism

Amino sugar and nucleotide sugar metabolism

Drug metabolism - other enzymes

Maturity onset diabetes of the young

ABC transporters

Inositol phosphate metabolism

Glutathione metabolism

Graft-versus-host disease

N-Glycan biosynthesis

RNA degradation

Allograft rejection

Proteasome

Taste transduction

Citrate cycle (TCA cycle)

Cysteine and methionine metabolism

Fructose and mannose metabolism

Glycerolipid metabolism

Androgen and estrogen metabolism

Fatty acid metabolism

Ether lipid metabolism

Dorso-ventral axis formation

Alanine

Base excision repair

aspartate and glutamate metabolism

Propanoate metabolism

Galactose metabolism

SNARE interactions in vesicular transport

Glycine

Nitrogen metabolism

serine and threonine metabolism

Linoleic acid metabolism

Butanoate metabolism

DNA replication

Asthma

Glycosaminoglycan degradation

Glycosphingolipid biosynthesis - lacto and neolacto series

Homologous recombination

Porphyrin and chlorophyll metabolism

Histidine metabolism

O-Glycan biosynthesis

Pentose phosphate pathway

Phenylalanine metabolism

Biosynthesis of unsaturated fatty acids

Renin-angiotensin system

beta-Alanine metabolism

Aminoacyl-tRNA biosynthesis

Circadian rhythm - mammal

Mismatch repair

Heparan sulfate biosynthesis

Nicotinate and nicotinamide metabolism

Non-homologous end-joining

One carbon pool by folate

Pentose and glucuronate interconversions

Primary bile acid biosynthesis

alpha-Linolenic acid metabolism

Ascorbate and aldarate metabolism

Glycosphingolipid biosynthesis - ganglio series

Glycosphingolipid biosynthesis - globo series

Other glycan degradation

Riboflavin metabolism

Steroid biosynthesis

Selenoamino acid metabolism

Basal transcription factors

C21-Steroid hormone metabolism

Terpenoid backbone biosynthesis

Limonene and pinene degradation

RNA polymerase

Glyoxylate and dicarboxylate metabolism

Keratan sulfate biosynthesis

Folate biosynthesis

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Protein export

Methane metabolism

Pantothenate and CoA biosynthesis

Sulfur metabolism

Chondroitin sulfate biosynthesis

Fatty acid elongation in mitochondria

Taurine and hypotaurine metabolism

Thiamine metabolism

leucine and isoleucine biosynthesis

Cyanoamino acid metabolism

Caffeine metabolism

Synthesis and degradation of ketone bodies

Vitamin B6 metabolism

D-Glutamine and D-glutamate metabolism

Ubiquinone and other terpenoid-quinone biosynthesis

Fatty acid biosynthesis

Phenylalanine

tyrosine and tryptophan biosynthesis

Biotin metabolism

D-Arginine and D-ornithine metabolism

Lipoic acid metabolism

Lysine biosynthesis

O-Mannosyl glycan biosynthesis

Puromycin

None

1

Yes

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