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cDNA Clones

Expression Plasmids

Mutant ORF Clones

Human

GCK

TSC2

PI 3 KINASE CATALYTIC SUBUNIT ALPHA

PRKACB

BRAF

SORBS1

CBL

KRAS

RAF1

EXOC7

NRAS

PRKAR1B

SOCS2

HRAS

JNK1

PIK3R5

PROTEIN KINASE A REGULATORY SUBUNIT I ALPHA

S6K1

P21 RAS

HEXOKINASE 1

JNK2

PKC ZETA

SHC

ACAT1

AKT1

B RAF

INSULIN

MAP2K2

MNK1

PI 3 KINASE P85 ALPHA

PRKAG2

A RAF

AKT2

AKT3

GLUCOKINASE

JNK3

PDPK1

PHKG1

PI 3 KINASE P55 GAMMA

AMPK GAMMA 1

CBLB

EIF4E

ELK1

ERK1

GSK3 BETA

IKK BETA

PCK2

PHKA1

SKIP

PHKG2

PPP1A

TUBERIN

AMPK ALPHA 1

CIP4

FBP1

HAMARTIN

INSULIN RECEPTOR

MAP2K1

MEK1

P38

SOCS4

BAD

CBL C

EIF4EL3

ERK2

G6PC2

GLUCOSE 6 PHOSPHATASE, CATALYTIC SUBUNIT

GLYCOGEN SYNTHASE 1

GRB2

LAR

PHOSPHORYLASE B

PIK3CB

PP1C GAMMA

PPP1R3B

PRKACA

PROTEIN PHOSPHATASE 1 BETA

PYGL

PYGM

SREBP1

GRF2

MNK2

PDE3A

PI 3 KINASE CATALYTIC SUBUNIT GAMMA

PKC IOTA

PTP1B

PYRUVATE KINASE

RAPTOR

SHIP

AMPK ALPHA 2

ESA1

FATTY ACID SYNTHASE

HEXOKINASE TYPE III

MEK2

P70 S6 KINASE BETA

PRKACG

PRKX

SH2B2

SOS2

ACACA

ACACB

Myc-DDK

Tag Free

TurboGFP

DDK-His

pCMV6-Entry

pCMV6-AC-GFP

pCMV6-XL5

pCMV6-XL4

pCMV6-AC

pCMV6-XL6

pCMV6-XL5-DDK-His

No

Yes

TrueORF

TrueClone

TrueORF Gold, TrueORF

Druggable Genome

Protein Kinase

ES Cell Differentiation/IPS

Transcription Factors

Phosphatase

Transmembrane

Secreted Protein

Stem cell - Pluripotency

Stem cell relevant signaling - JAK/STAT signaling pathway

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Regulation of actin cytoskeleton

Focal adhesion

Cytokine-cytokine receptor interaction

Neuroactive ligand-receptor interaction

Insulin signaling pathway

Endocytosis

Colorectal cancer

Calcium signaling pathway

Ubiquitin mediated proteolysis

Chemokine signaling pathway

Neurotrophin signaling pathway

Olfactory transduction

Wnt signaling pathway

Prostate cancer

Huntington's disease

Pancreatic cancer

Endometrial cancer

Tight junction

Natural killer cell mediated cytotoxicity

Progesterone-mediated oocyte maturation

Alzheimer's disease

Purine metabolism

Jak-STAT signaling pathway

Melanoma

Axon guidance

ErbB signaling pathway

Cell cycle

p53 signaling pathway

B cell receptor signaling pathway

Leukocyte transendothelial migration

T cell receptor signaling pathway

Vascular smooth muscle contraction

Fc epsilon RI signaling pathway

Glioma

GnRH signaling pathway

Apoptosis

Chronic myeloid leukemia

Melanogenesis

Adherens junction

Oocyte meiosis

mTOR signaling pathway

Small cell lung cancer

Cell adhesion molecules (CAMs)

Renal cell carcinoma

Non-small cell lung cancer

Fc gamma R-mediated phagocytosis

Gap junction

Dilated cardiomyopathy

Type II diabetes mellitus

Lysosome

VEGF signaling pathway

Toll-like receptor signaling pathway

Thyroid cancer

Long-term potentiation

Acute myeloid leukemia

Long-term depression

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Bladder cancer

Hypertrophic cardiomyopathy (HCM)

Mismatch repair

Glycolysis / Gluconeogenesis

Spliceosome

Parkinson's disease

Hematopoietic cell lineage

Pyrimidine metabolism

Oxidative phosphorylation

Systemic lupus erythematosus

Phosphatidylinositol signaling system

Adipocytokine signaling pathway

Viral myocarditis

Amino sugar and nucleotide sugar metabolism

PPAR signaling pathway

Primary immunodeficiency

Starch and sucrose metabolism

Amyotrophic lateral sclerosis (ALS)

TGF-beta signaling pathway

ECM-receptor interaction

Antigen processing and presentation

Cardiac muscle contraction

Basal cell carcinoma

NOD-like receptor signaling pathway

Epithelial cell signaling in Helicobacter pylori infection

Ribosome

Homologous recombination

Glycerophospholipid metabolism

Inositol phosphate metabolism

RIG-I-like receptor signaling pathway

Complement and coagulation cascades

Vibrio cholerae infection

Notch signaling pathway

Pathogenic Escherichia coli infection

Galactose metabolism

Drug metabolism - cytochrome P450

Maturity onset diabetes of the young

Metabolism of xenobiotics by cytochrome P450

Dorso-ventral axis formation

RNA degradation

Cytosolic DNA-sensing pathway

Arginine and proline metabolism

Taste transduction

Hedgehog signaling pathway

Arachidonic acid metabolism

Glutathione metabolism

Drug metabolism - other enzymes

Retinol metabolism

Valine

Nucleotide excision repair

Tyrosine metabolism

N-Glycan biosynthesis

Pyruvate metabolism

Glycerolipid metabolism

Fatty acid metabolism

Lysine degradation

Autoimmune thyroid disease

Proteasome

Citrate cycle (TCA cycle)

leucine and isoleucine degradation

Base excision repair

Sphingolipid metabolism

ABC transporters

Prion diseases

Type I diabetes mellitus

Cysteine and methionine metabolism

Tryptophan metabolism

Graft-versus-host disease

Fructose and mannose metabolism

Porphyrin and chlorophyll metabolism

Propanoate metabolism

DNA replication

Aminoacyl-tRNA biosynthesis

SNARE interactions in vesicular transport

Glycosphingolipid biosynthesis - lacto and neolacto series

Alanine

aspartate and glutamate metabolism

Androgen and estrogen metabolism

Allograft rejection

Ether lipid metabolism

Basal transcription factors

Histidine metabolism

Selenoamino acid metabolism

Glycine

serine and threonine metabolism

Pentose phosphate pathway

Butanoate metabolism

Nitrogen metabolism

Regulation of autophagy

RNA polymerase

Phenylalanine metabolism

Glycosaminoglycan degradation

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

O-Glycan biosynthesis

Linoleic acid metabolism

Pentose and glucuronate interconversions

Asthma

Nicotinate and nicotinamide metabolism

Keratan sulfate biosynthesis

One carbon pool by folate

beta-Alanine metabolism

Ascorbate and aldarate metabolism

Biosynthesis of unsaturated fatty acids

Pantothenate and CoA biosynthesis

Steroid biosynthesis

Heparan sulfate biosynthesis

Riboflavin metabolism

Chondroitin sulfate biosynthesis

Primary bile acid biosynthesis

Other glycan degradation

Sulfur metabolism

alpha-Linolenic acid metabolism

Terpenoid backbone biosynthesis

Renin-angiotensin system

Glyoxylate and dicarboxylate metabolism

Non-homologous end-joining

Glycosphingolipid biosynthesis - ganglio series

Glycosphingolipid biosynthesis - globo series

Limonene and pinene degradation

Circadian rhythm - mammal

Cyanoamino acid metabolism

Taurine and hypotaurine metabolism

Protein export

leucine and isoleucine biosynthesis

Folate biosynthesis

Thiamine metabolism

C21-Steroid hormone metabolism

Caffeine metabolism

Synthesis and degradation of ketone bodies

Fatty acid elongation in mitochondria

Fatty acid biosynthesis

Methane metabolism

Ubiquinone and other terpenoid-quinone biosynthesis

Lipoic acid metabolism

Lysine biosynthesis

Phenylalanine

tyrosine and tryptophan biosynthesis

O-Mannosyl glycan biosynthesis

D-Glutamine and D-glutamate metabolism

Vitamin B6 metabolism

Biotin metabolism

D-Arginine and D-ornithine metabolism

Neomycin

None

1

Yes

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