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cDNA Clones

Expression Plasmids

Mutant ORF Clones

Human

AKT1

P53

CD51

PI 3 KINASE CATALYTIC SUBUNIT ALPHA

PI 3 KINASE P85 ALPHA

PTEN

AKT2

AKT3

C-MYC

CDK4

CDKN1B

COX2

CYCLIN D1

CYCLIN E1

E2F1

INOS

INTEGRIN BETA 1

LAMININ

LAMININ 2 ALPHA

NF-KB P65

P15 INK4B

PI 3 KINASE P85 BETA

PIK3CB

PIK3CD

RETINOID X RECEPTOR GAMMA

SKP2

TRAF3

TRAF6

TurboGFP

Myc-DDK

pCMV6-AC-GFP

pCMV6-Entry

pCMV6-AC-Myc-DDK

No

Yes

TrueClone

TrueORF Gold, TrueORF

TrueORF

Druggable Genome

ES Cell Differentiation/IPS

Transcription Factors

Protein Kinase

Stem cell - Pluripotency

Transmembrane

Phosphatase

Stem cell relevant signaling - DSL/Notch pathway

Stem cell relevant signaling - JAK/STAT signaling pathway

Stem cell relevant signaling - Wnt Signaling pathway

Embryonic stem cells

Induced pluripotent stem cells

Nuclear Hormone Receptor

Stem cell relevant signaling - TGFb/BMP signaling pathway

Pathways in cancer

Metabolic pathways

MAPK signaling pathway

Focal adhesion

Neuroactive ligand-receptor interaction

Prostate cancer

Endocytosis

Colorectal cancer

Melanoma

Regulation of actin cytoskeleton

Cytokine-cytokine receptor interaction

Calcium signaling pathway

Chemokine signaling pathway

ErbB signaling pathway

Endometrial cancer

Glioma

Neurotrophin signaling pathway

Renal cell carcinoma

Jak-STAT signaling pathway

Non-small cell lung cancer

Pancreatic cancer

Axon guidance

Chronic myeloid leukemia

T cell receptor signaling pathway

Insulin signaling pathway

Natural killer cell mediated cytotoxicity

Wnt signaling pathway

Acute myeloid leukemia

Bladder cancer

Melanogenesis

VEGF signaling pathway

GnRH signaling pathway

Gap junction

Progesterone-mediated oocyte maturation

Adherens junction

Toll-like receptor signaling pathway

B cell receptor signaling pathway

Cell adhesion molecules (CAMs)

Fc epsilon RI signaling pathway

Apoptosis

Small cell lung cancer

Fc gamma R-mediated phagocytosis

Leukocyte transendothelial migration

Cell cycle

Alzheimer's disease

Tight junction

Long-term potentiation

Huntington's disease

Adipocytokine signaling pathway

p53 signaling pathway

Thyroid cancer

Vascular smooth muscle contraction

mTOR signaling pathway

Long-term depression

Epithelial cell signaling in Helicobacter pylori infection

Purine metabolism

Type II diabetes mellitus

Hematopoietic cell lineage

Basal cell carcinoma

TGF-beta signaling pathway

Oocyte meiosis

Dorso-ventral axis formation

Ubiquitin mediated proteolysis

Pathogenic Escherichia coli infection

Phosphatidylinositol signaling system

ECM-receptor interaction

Glutathione metabolism

NOD-like receptor signaling pathway

Notch signaling pathway

Amyotrophic lateral sclerosis (ALS)

Lysosome

Prion diseases

RIG-I-like receptor signaling pathway

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Dilated cardiomyopathy

ABC transporters

Hypertrophic cardiomyopathy (HCM)

PPAR signaling pathway

Viral myocarditis

Hedgehog signaling pathway

Inositol phosphate metabolism

Sphingolipid metabolism

Parkinson's disease

Systemic lupus erythematosus

Antigen processing and presentation

Arachidonic acid metabolism

Cytosolic DNA-sensing pathway

Glycolysis / Gluconeogenesis

Pyrimidine metabolism

Type I diabetes mellitus

Allograft rejection

Autoimmune thyroid disease

Citrate cycle (TCA cycle)

Graft-versus-host disease

Maturity onset diabetes of the young

Metabolism of xenobiotics by cytochrome P450

Complement and coagulation cascades

Drug metabolism - cytochrome P450

Fatty acid metabolism

Lysine degradation

Spliceosome

Base excision repair

Cysteine and methionine metabolism

Glycerophospholipid metabolism

Homologous recombination

Pyruvate metabolism

Retinol metabolism

Glycerolipid metabolism

Mismatch repair

Starch and sucrose metabolism

Linoleic acid metabolism

Nicotinate and nicotinamide metabolism

Primary immunodeficiency

Vibrio cholerae infection

Arginine and proline metabolism

Cardiac muscle contraction

Drug metabolism - other enzymes

N-Glycan biosynthesis

Nucleotide excision repair

RNA degradation

Tryptophan metabolism

Ether lipid metabolism

Galactose metabolism

Olfactory transduction

Oxidative phosphorylation

Ribosome

SNARE interactions in vesicular transport

Tyrosine metabolism

Valine

Alanine

Asthma

Biosynthesis of unsaturated fatty acids

DNA replication

Glycosaminoglycan degradation

Pantothenate and CoA biosynthesis

Regulation of autophagy

Renin-angiotensin system

Taste transduction

aspartate and glutamate metabolism

Fructose and mannose metabolism

Glycosphingolipid biosynthesis - ganglio series

Glycosphingolipid biosynthesis - lacto and neolacto series

Heparan sulfate biosynthesis

Pentose phosphate pathway

Propanoate metabolism

alpha-Linolenic acid metabolism

leucine and isoleucine biosynthesis

leucine and isoleucine degradation

Amino sugar and nucleotide sugar metabolism

Aminoacyl-tRNA biosynthesis

Androgen and estrogen metabolism

Butanoate metabolism

C21-Steroid hormone metabolism

Circadian rhythm - mammal

D-Glutamine and D-glutamate metabolism

Glycine

Glycosphingolipid biosynthesis - globo series

Nitrogen metabolism

O-Glycan biosynthesis

Other glycan degradation

Phenylalanine metabolism

RNA polymerase

Riboflavin metabolism

serine and threonine metabolism

Caffeine metabolism

Chondroitin sulfate biosynthesis

Fatty acid biosynthesis

Folate biosynthesis

Histidine metabolism

Keratan sulfate biosynthesis

Limonene and pinene degradation

Lysine biosynthesis

Non-homologous end-joining

Porphyrin and chlorophyll metabolism

Proteasome

Selenoamino acid metabolism

Steroid biosynthesis

Sulfur metabolism

Synthesis and degradation of ketone bodies

Taurine and hypotaurine metabolism

Terpenoid backbone biosynthesis

beta-Alanine metabolism

Neomycin

1

Yes

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