IL6R Human Recombinant Protein
CAT#: TP728035
Biotinylated Human IL-6RA (C-Avi-6His)
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CNY 6,530.00
货期*
2周
规格
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经常一起买 (1)
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Specifications
Product Data | |
Species | Human |
Protein Source | Human |
Expression cDNA Clone or AA Sequence |
Leu20-Pro365
|
Tag | C-Avi-6His |
Buffer | Lyophilized from a 0.2 um filtered solution of PBS,pH7.4. |
Note | Biotinylated Recombinant Human Interleukin-6 receptor subunit alpha is produced by our Mammalian expression system and the target gene encoding Leu20-Pro365 is expressed with a AVI, 6His tag at the C-terminus. |
Stability | 12 months from date of despatch |
Reference Data | |
Locus ID | 3570 |
UniProt ID | P08887 |
Summary | Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. IL6Ra is a part of the receptor for interleukin 6 cytokine. IL6Ra binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitates an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis. Low concentration of a soluble form of IL6 receptor acts as an agonist of IL6 activity. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. |
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