Cynomolgus Recombinant Protein

Specifications

Product Data
Species	Cynomolgus
Protein Source	E. coli
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) M1-H317
Tag	C-His
Buffer	Supplied as a 0.2 μm filtered solution of 20mM sodium phosphate, pH7.8.
Note	Recombinant Cyno ApoE is produced by our E. coli expression system and the target gene encoding M1-H317 is expressed with a His tag at the C-terminus.
Stability	12 months from date of despatch
Reference Data
Summary	Apolipoprotein E (ApoE) is a glycoprotein that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. ApoE can be synthesized by the liver and intestinally synthesized chylomicrons. ApoE mediates high-affinity binding of chylomicrons and very low density lipoprotein (VLDL) particles to the LDL receptor, allowing for specific uptake of these particles by the liver, preventing the accumulation of cholesterol-rich particles in the plasma. ApoE plays an essential role in the formation of plasma lipoproteins and is involved in their production, conversion and clearance. ApoE is also a constituent of a subclass of high density of lipoproteins (HDL) involved in cholesterol transport.

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