Aurora A (AURKA) Human Recombinant Protein

Specifications

Product Data
Species	Human
Protein Source	E. coli
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Glu122-Ser403
Tag	C-6His
Buffer	Supplied as a 0.2 um filtered solution of 50mM Tris, 100mM NaCl, 10%glycerol, 1mM DTT, pH7.4.
Note	Recombinant Human AuroraA (122-403) is produced by our mammalian expression system and the target gene encoding Glu122-Ser403 is expressed with a His tag at the C terminus.
Stability	12 months from date of despatch
Reference Data
Locus ID	6790
UniProt ID	O14965
Summary	AuroraA is a part of the protein kinase superfamily. AuroraA is a serine/threonine kinase that contributes to the regualtion of cell cycle progression while also playing critical roles in various mitotic events like cytokinesis. This protein is required for both the intitation of activating CDK1 at the centrosomes and normal axon formation. AuroraA also phosphorylates its own inhibitors to inhibit their activity.

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