SARS-CoV-2 Recombinant Protein
CNY 6,810.00
货期*
2周
规格
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Specifications
Product Data | |
Species | SARS-CoV-2 |
Protein Source | E. coli |
Expression cDNA Clone or AA Sequence |
Ala1-Gln198
|
Tag | C-TEV-8His |
Buffer | Supplied as a 0.2 um filtered solution of 20mM Tris, 150mM NaCl, 10%Glycerol, 4mM MgCl2, pH8.0 |
Note | Recombinant SARS-CoV-2 NSP8 is produced by our E.coli expression system and the target gene encoding Ala1-Gln198 is expressed with a 8His tag at the C-terminus. |
Stability | 12 months from date of despatch |
Reference Data | |
Summary | The replication of coronavirus is operated by a set of non-structural proteins (nsps) encoded by open reading frame 1a (ORF1a) and ORF1ab in its genome. NSP8 is a component of the coronavirus replicase polyprotein that forms a replication complex. It can form a dimer with NSP7 and subsequently assembles into a large hexadecameric structure, which participates in viral replication by acting as a primase. NSP8 was shown to have RNA-dependent RNA polymerase (RdRp) activity that is necessary for producing primers utilized by NSP12 which is normally accepted to be the RdRp for SARS-CoV. |
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