IL36 gamma (IL36G) Human Recombinant Protein
CAT#: TP724898
Recombinant Human Interleukin-36 gamma/IL-36G
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CNY 3,420.00
货期*
2周
规格
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经常一起买 (1)
IL1F9 (IL36 gamma) mouse monoclonal antibody, clone OTI2F4 (formerly 2F4)
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Specifications
Product Data | |
Species | Human |
Protein Source | E. coli |
Expression cDNA Clone or AA Sequence |
Ser18-Asp169
|
Buffer | Lyophilized from a 0.2 um filtered solution of 20mM Tris, 100mM NaCl, 0.1mM EDTA, pH8.0 |
Note | Recombinant Human Interleukin-36 gamma is produced by our E.coli expression system and the target gene encoding Ser18-Asp169 is expressed. |
Stability | 12 months from date of despatch |
Reference Data | |
Locus ID | 56300 |
UniProt ID | Q9NZH8 |
Summary | Interleukin-36 gamma (IL-36γ) belongs to the interleukin 1 cytokine family that includes three closely related genes, IL-36α, β, and γ, formerly known as IL-1F6, F8, and F9 respectively. IL-36α has been found in both neuronal and synovial tissue, while IL-36β and IL-36γ are expressed in both cutaneous and mucosal epithelial cells of the respiratory tract. IL-36β and IL-36γ facilitate proliferation, maturation, and cytokine expression by innate immune cells (such as keratinocytes and dendritic cells), and adaptive immune cells (neutrophils and T-cells) in both humans and mice. The activity of IL-36α is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2) and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). IL-36γ plays an essential role in communicating cell death to surrounding cells. |
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