Elastase 3A (CELA3A) Human Recombinant Protein

Specifications

Product Data
Species	Human
Protein Source	Human 293
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Ser16-His270
Tag	C-6His
Buffer	Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 150mM NaCl, 10%Glycerol, pH7.5
Note	Recombinant Human Chymotrypsin-Like Elastase Family Member 3A is produced by our Mammalian expression system and the target gene encoding Ser16-His270 is expressed with a 6His tag at the C-terminus.
Storage	Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
Stability	12 months from date of despatch
Reference Data
Locus ID	10136
UniProt ID	P09093
Summary	Chymotrypsin-Like Elastase Family Member 3A (CELA3A) is an enzyme that belongs to the subfamily of serine proteases. Serine proteases hydrolyze many proteins in addition to elastin. ELA3A is secreted from the pancreas as a zymogen. Humans have six elastase genes that encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, ELA3A has little elastolytic activity. However, ELA3A is an efficient protease that preferentially cleaves proteins after alanine residues. Elastase 3A may also engage in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1.

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