Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Protein Source	Human
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Phe69-Leu244
Tag	C-Mouse Fc
Buffer	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Note	Recombinant Mouse Dectin-1 (C-mFc) is produced by Human Cells. The target gene encoding Phe69-Leu244 is expressed with a C-mFc tag.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability	12 months from date of despatch
Reference Data
RefSeq	NP_064392.2（Q6QLQ4）
Summary	Dectin-1 was recently identified as the most important receptor for beta-glucan. It is a type II transmembrane protein which binds beta-1,3 and beta-1,6 glucans, and is expressed on most cells of the innate immune system and has been implicated in phagocytosis as well as killing of fungi by macrophages, neutrophils and dendritic cells. Recognition of beta-glucan by dectin-1 triggers effective immune response, including phagocytosis and proinflammatory factor production, to eliminate infecting fungi, which especially benefits immunocompromised patients against opportunistic fungal infection.

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