FH (NM_000143) Human Recombinant Protein

CAT#: TP720199M

Recombinant protein of human fumarate hydratase (FH), nuclear gene encoding mitochondrial protein

Size: 10 ug 50 ug 500 ug 1 mg



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CNY 7,220.00


货期*
2周

规格
    • 50 ug

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经常一起买 (1)
FH (Fumarate Hydratase) mouse monoclonal antibody, clone OTI1F10 (formerly 1F10)
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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Tag Tag Free
Predicted MW 50.2 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Supplied as a 0.2 um filtered solution of 20mM Tris, pH 8.0.
Storage Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Stability Stable for at least 3 months from date of receipt under proper storage and handling conditions.
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Reference Data
RefSeq NP_000134
Locus ID 2271
UniProt ID P07954, A0A0S2Z4C3
Cytogenetics 1q43
Synonyms FMRD; HLRCC; HsFH; LRCC; MCL; MCUL1
Summary The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
Protein Pathways Citrate cycle (TCA cycle), Metabolic pathways, Pathways in cancer, Renal cell carcinoma
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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