4930432K21Rik (NM_029045) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR209310 protein sequence Red=Cloning site Green=Tags(s) MNKKKQRNSGVGLHPSKPSKNPRLRDSHSSMMVHSHYSRESEDSSEPAPSVELGGEEPLHEAFSCPVEDT GAASDLAGSPKELVPLPPSQNSVGKFVPQFAKPRKTVTRKAKAWEEDLEGCTTSQETRPELGALKAASQP QRESLRFPPHDIRPEVQTQPDGTLSKERTISLDNRSLGNNGFEMATVQDSSSPLSDAAAEGREADSRDPQ ERDAQGGEAGAQHSGEPQEGEDILYTSALAPASEPTWSVAQDLSVPTYTLSSTAAAPSSTSPADASLMDT VITEASLDPSVLQQSAPQVAKLLGSLDEQIPDGGCIGTLLSSTPLAEETTAGREEARWEERCHGDTLASF TETEPEKQEPVTEAGDSGHIAQEMDPVVKTKDSGSDEQSPGDIGMLPLPAQSMNQMLVELRGLTCDQDLE GLSTPHTSSQLEHTCAASDPPQSTKDCHSSPGIPVHLAAPCPRDQAAWQESSAMELDFLPDSQIQDALDA TNMEQGFPSGSMPDLGWPVPSSQSIGGSPKAVTKPQSRSHVETWAQETYRMQDATDTVRGLVVELSGLNR LIMSTHRDLEAFKRRKTKSLPYLTKGLGSLPRGDQSWRDL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	64.4 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_083321
Locus ID	74666
UniProt ID	Q6DIA7, E9QNR8, A0A0R4J144
Refseq Size	2494
Cytogenetics	8 C2
Refseq ORF	1803
Summary	Meiotic recombination factor component of recombination bridges involved in meiotic double-strand break repair (PubMed:32463460, PubMed:32460033). Modulates the localization of recombinases DMC1:RAD51 to meiotic double-strand break (DSB) sites through the interaction with and stabilization of the BRCA2:HSF2BP complex during meiotic recombination (PubMed:32460033, PubMed:32463460). Indispensable for the DSB repair, homologous synapsis, and crossover formation that are needed for progression past metaphase I, is essential for spermatogenesis and male fertility (PubMed:32463460, PubMed:32460033).[UniProtKB/Swiss-Prot Function]

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